Osteoporosis Clinical Trials

Showing 21-40 of 535 trials

Validating Osteoporosis Detection in Rho AI Software

NCT06830005

To assess the effectiveness of 16bit's Rho AI (artificial intelligence) software at identifying known cases of osteoporosis. 800 de-identified images from January 2007 to January 2024 will be accessed to test the software prospectively.

Osteopenia or Osteoporosis

University of Wisconsin, Madison800 participantsStarted Jun 2025

Madison, Wisconsin, United States

Active Not RecruitingPhase 4

Muscle Impact of Treating Osteoporosis

NCT05666310

Osteosarcopenia is a geriatric musculoskeletal syndrome characterized by co-existence of osteoporosis and sarcopenia (low skeletal muscle mass, strength, and/or functional capacity). There is strong evidence of overlap between the pathophysiology of osteoporosis and sarcopenia (muscle-bone crosstalk). This research plan will further explore the relationship between bone and muscle, and provide new information about effect of osteoporosis medications on muscle health in older adults who are under treatment for osteoporosis.

SarcopeniaOsteoporosis

Nami Safai Haeri20 participantsStarted Feb 2023

Pittsburgh, Pennsylvania, United States

RECRUITINGPhase 2

Role of Estrogen on Skeletal Outcomes in FHA

NCT07010146

The purpose of this study is to assess whether the natural form of estrogen (17-beta estradiol) given as a patch so that it is absorbed through your skin, is better at improving bone strength over 1 year than natural estrogen (17-beta estradiol) taken by mouth, or a synthetic form oestrogen (ethinyl estradiol) given as a patch that also provides birth control. Participants will: Take estrogen for 1 year either (i) in its natural form as a patch twice a week (and progesterone by mouth for 12 days of each month), or (ii) in its natural form as a pill daily (and progesterone by mouth for 12 days of each month), or (iii) in a synthetic form as a birth control patch weekly for 3 weeks with 1 week off the patch. You will not be able to choose which form of estrogen you will receive as this will be assigned to you based on a pre-existing randomization sequence (like the flip of a coin) Take provided calcium and vitamin D supplements Attend 4 study visits over 12 months with two at the beginning and then every 6 months that include: History and Physical Exams Lab Work Imaging studies Questionnaires Dietary recalls

Bone StrengthBone DensityFHA (Functional Hypothalamic Amenorrhea)

University of Virginia150 participantsStarted Jul 2025

Charlottesville, Virginia, United States • Charlottesville, Virginia, United States

Validating Osteoporosis Detection in Rho AI Software

Muscle Impact of Treating Osteoporosis

Role of Estrogen on Skeletal Outcomes in FHA

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