Multiple Sclerosis Clinical Trials

Showing 1421-1440 of 5,960 trials

Study of MK-3475 (Pembrolizumab) in Patients With Microsatellite Unstable (MSI) Tumors (Cohort D)

NCT04098068

This study will be looking at whether MK-3475 (pembrolizumab) is effective (anti-tumor activity) and safe in patients with MSI (Microsatellite Unstable) negative cancer with a mutator phenotype.

High Tumor Mutation BurdenHigh TMB (Tumor Mutation Burden)MSS (Microsatellite Stable)

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins12 participantsStarted Jan 2018

Baltimore, Maryland, United States • New York, New York, United States • Columbus, Ohio, United States

COMPLETEDNA

Effects of Virtual Reality Exercise on Promoting Physical Activity and Health Among College Students

NCT06902727

The purpose of this research is to examine the effectiveness of a 4-week immersive-virtual reality (VR) exercise bike intervention on college students' physiological outcomes (physical activity levels, cardiovascular fitness, and body composition) and psychological outcomes (situational motivation, situational interest, mood states, and depressive symptoms).

Physical Activity LevelsCardiovascular FitnessBody Composition+4 more

The University of Tennessee, Knoxville36 participantsStarted Sep 2020

Minneapolis, Minnesota, United States

RECRUITINGPhase 2

Open Label Phase 2 Basket Trial With Atezolizumab and Tiragolumab in Solid Tumors

NCT05483400

In this open label phase II trial combination therapy with the anti-PD-L1 antibody atezolizumab and the anti-TIGIT antibody tiragolumab will be investigated in patients with localized HNSCC who will undergo surgery, advanced or metastatic MSI-H cancer, PD-1 resistant metastatic melanoma, and patients with a locally advanced or metastatic solid tumor who, in the opinion of the investigator, based on available clinical data, may benefit from treatment with anti-PD-L1 and anti-TIGIT immunotherapy.

Head and Neck NeoplasmsMSI-H CancerMelanoma

University Medical Center Groningen97 participantsStarted Oct 2023

Groningen, Netherlands

Study of MK-3475 (Pembrolizumab) in Patients With Microsatellite Unstable (MSI) Tumors (Cohort D)

Effects of Virtual Reality Exercise on Promoting Physical Activity and Health Among College Students

Open Label Phase 2 Basket Trial With Atezolizumab and Tiragolumab in Solid Tumors

Related Searches

Dose Individualization of Antineoplastic Drugs and Anti-Infective Drug in Children With Hematoplastic Disease

Biomarkers for Predicting Neoadjuvant Chemoradio-resistance for Middle-low Advanced Rectal Cancer

Increasing Patient Comfort in Palliative Radiotherapy With a Newly Developed Mattress - A Prospective Clinical Study

A Wheelchair Propulsion Training Program

Immunotherapy With Y90-RadioEmbolization for Metastatic Colorectal Cancer

Cluster RCT of Cognitive Behavioral Therapy to Support Caregivers of Older Adults in Hong Kong

A Study of Allogeneic Hematopoietic Cell Transplantation for Primary Progressive Multiple Sclerosis

Kids FACE FEARS Comparative Effectiveness Research

A Study of Multiple Sclerosis Routine Clinical Practice: Impact on Adherence and Clinical Outcomes of Ofatumumab Treated Patients

The Australia and New Zealand Multicentre Upper Gastrointestinal Endoscopic Tissue Resection Study

Efficacy of Emotionally Focused Therapy Among Spanish Speaking Couples

Gastric-type Endocervical Adenocarcinoma: a Population-based Cohort Study

A Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of Co-Administration of Roluperidone and Olanzapine in Adult Subjects With Moderate to Severe Negative Symptoms of Schizophrenia

A Canadian Study of Persistence on Ofatumumab Using Patient Support Program Data

Monitoring of patIents With Microdialysis Following Pancreaticoduodenectomy

Targeted Α-synuclein PET Imaging in the Diagnosis of Multiple System Atrophy

ALTTO (Adjuvant Lapatinib And/Or Trastuzumab Treatment Optimisation) Study; BIG 2-06/N063D