Multiple Sclerosis Clinical Trials

Showing 101-120 of 5,870 trials

Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to Radiotherapy

NCT05308732

This study aims to propose an alternative and auxiliary methodology for the prevention and treatment of Oral Mucositis (OM) in patients undergoing radiotherapy or radio and chemotherapy for head and neck neoplasms through the use of copaiba-based mouthwash, since the treatment that currently has proven efficacy for the prevention of OM(Low Power Laser Therapy) cannot be applied in tumor regions due to the risk of stimulating the tissue proliferation of malignant cells.

Head and Neck NeoplasmsMucositis OralRadiotherapy; Complications

Instituto Nacional de Cancer, Brazil20 participantsStarted May 2021

Rio de Janeiro, Rio de Janeiro, Brazil

RECRUITINGNA

The Impact of Melatonin Lotion on Sleep and Mental Health

NCT06768749

The purpose of this study is to examine the effect that melatonin lotion has on sleep quality, the nervous system, and mental health. Melatonin is a hormone secreted by the brain that regulates sleep and might improve depression and anxiety symptoms. The goal is to determine whether melatonin in lotion form is an effective treatment for young adults with inadequate sleep and might improve mental health. Participants will fill out surveys, wear an actigraph (a wrist-worn device that measures sleep), wear a heart rate monitor (a strap worn around one's chest), and provide nightly saliva samples during treatment weeks. In one of the two treatment weeks, participants will receive a lotion that contains melatonin. During the other week they will receive a control treatment that will be lotion with no melatonin, and there will be a week in between with no treatment at all.

Sleep ProblemsDepressive Disorder and Anxiety Disorders

University of Redlands60 participantsStarted Feb 2025

Redlands, California, United States

Safety and Tolerability of the Use of Copaiba in Patients With Oral Cancer Submitted to Radiotherapy

The Impact of Melatonin Lotion on Sleep and Mental Health

Related Searches

Clinicopathologic Features and Staging Risk Factors of Early-Onset Colorectal Cancer

Evaluation and Implementation Preparation of a Proactive Palliative Care Model (ENABLE-SG)

Activating Social Resources in Psychotherapy-Seeking Individuals: Effectiveness and Timing of a Social Support Just-in-Time Adaptive Intervention

Biospecimen Procurement for Head and Neck Disorders

Efficacy and Safety of Transcranial dIrect Current stiMulation in Multiple System Atrophy-Cerebellar Variant

An International Multicenter Clinical Study on Application of UroMed AI Doctor Based on Large Language Models

Evaluating the Impact of Psychoeducation and Sleep-informed Workshop Targeting Sleep Concerns in Women and Individuals With Premenstrual Dysphoric Disorder

Development of a Pan-Cancer Screening Model Based on Blood Biomarkers

Impact of Oral Versus Intravenous 5-FU-Based Adjuvant Regimens on Sleep Quality and Depression in Patients With Gastrointestinal Cancers

Cognitive Musical Screening and Therapeutic Innovation in Multiple Sclerosis

My Best GI Eating Study

Comparative PK, PD, Efficacy, and Safety Assessment of the Proposed Ocrelizumab Biosimilar CYB704 and Ocrevus in Participants With Relapsing Multiple Sclerosis

MindfulCityU-- A Mindfulness Mobile Application for Promoting University Students' Mental Health

Online Self-healing Program

Lu-177-DOTATATE (Lutathera) in Therapy of Inoperable Pheochromocytoma/ Paraganglioma

A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Preliminary Anticancer Activity of GSK4524101 Alone or With Niraparib in Participants With Solid Tumors

Phase I Trial of 4'-Thio-2'-Deoxycytidine (TdCyd) in Patients With Advanced Solid Tumors

Continuous Temperature Monitoring (CTM) for Cytokine Release Syndrome (CRS), an Immune-Related Adverse Event