Multiple Sclerosis Clinical Trials

Showing 5341-5360 of 5,960 trials

Sodium Intake in Multiple Sclerosis

NCT01846234

Recently, it has been shown that salt (ClNa, sodium chloride) can modulate the differentiation of human and mouse TH17 cells. Indeed, mice feed with high sodium diet were described to develop more aggressive course of EAE (Experimental Autoimmune Encephalitis). However, the role of sodium intake in MS has not been investigated. In this study we investigate the effect of sodium intake in Multiple Sclerosis (MS) clinical and radiological activity.

Multiple Sclerosis

Fundación para la Lucha contra las Enfermedades Neurológicas de la Infancia132 participantsStarted Nov 2010

Buenos Aires, Argentina

COMPLETEDPhase 2

Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis

NCT01281696

The main purpose of this study is to investigate the efficacy of bevacizumab, etoposide and cisplatin in treating breast cancer patients with central nervous system metastasis (including brain parenchymal and leptomeningeal metastasis).

Breast NeoplasmsLeptomeningeal MetastasisBrain Metastases

National Taiwan University Hospital40 participantsStarted Jan 2011

Taipei, Taipei City, Taiwan

COMPLETEDPhase 1

Dose Escalation, Safety and Pharmacokinetic Study of AVE8062 Combined With Docetaxel and Cisplatin in Patients With Solid Tumors

NCT01095302

Primary Objective: * To determine the maximum tolerated dose based on the incidence of dose limiting toxicity and the maximum administered dose of ombrabulin in combination with docetaxel and cisplatin administered every 3 weeks in patients with advanced solid tumors Secondary Objectives: * To assess the overall safety profile of the combination therapy * To characterize the pharmacokinetic profile of ombrabulin, its active metabolite RPR 258063, docetaxel and cisplatin in combination. * To evaluate anti-tumor activity of the combination therapy

Neoplasms, Malignant

Sanofi11 participantsStarted May 2010

Akashi-Shi, Japan • Kōtoku, Japan • Nagoya, Japan

Sodium Intake in Multiple Sclerosis

Bevacizumab With Etoposide and Cisplatin in Breast Cancer Patients With Brain and/or Leptomeningeal Metastasis

Dose Escalation, Safety and Pharmacokinetic Study of AVE8062 Combined With Docetaxel and Cisplatin in Patients With Solid Tumors

Related Searches

To Assess the Prevalence of Spasticity and the Impact on the Quality of Life in Multiple Sclerosis Patients

Impact of Armodafinil on Neurocognition and Cognitive Fatigue in Multiple Sclerosis (MS)

Marijuana for Cancer Pain

Phase II Trial of Oxaliplatin in Combination With S-1(SOX) in Patients With Recurrent or Metastatic Breast Cancer

Tetracycline-Derivatives for Treatment of Cerebral Arteriovenous Malformations and Aneurysms

Anti-Inflammatory Type II Monocyte Induction by Glatiramer Acetate (Copaxone) Treatment of Multiple Sclerosis

P53 in Differentiated Thyroid Cancer

7-Hydroxystaurosporine and Perifosine in Treating Patients With Relapsed or Refractory Acute Leukemia, Chronic Myelogenous Leukemia or High Risk Myelodysplastic Syndromes

Xerotic Dermatitis in Aged People

Lokomat Training Effects on MS Gait Abnormalities

Light-Emitting Diode Therapy in Preventing Mucositis in Children Receiving Chemotherapy With or Without Radiation Therapy Before Bone Marrow Transplantation

Hormone Replacement Therapy and the Risk of Breast Cancer Recurrence in Women With Previous Early Stage Breast Cancer

Treatment Interruption of Natalizumab

An Open-label Phase II Study With SUTENT in Patients Suffering From Hormone Refractory Prostate Cancer

A Study for Patients With Recurrent or Metastatic Squamous Cell Head and Neck Cancer

Evaluation of Endoscopic Submucosal Dissection (ESD) Efficacy

An Observational Study for the Assessment of Adherence, Effectiveness and Convenience of Rebif® Treatment in Relapsing Multiple Sclerosis Patients Using RebiSmart™.