Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
US Department of Veterans Affairs
Age
18–75
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
1. Diagnosis of MS by McDonald criteria
2. Ability to clearly understand written and oral direction in English
3. Self-reported gait problem
4. One or more falls in the past 6 months
5. The ability to walk 25 feet with no more than a cane for assistance (The subject must be comfortable using a cane)
6. Age 18-70
7. Written informed consent to participate in the study
8. Approval from subject's primary care physician for physical activity
You may not be if
1. No relapse within the last 3 months
2. No more than two relapses within the past 12 months
3. Recent myocardial infarction
4. Uncontrolled hypertension or diabetes
5. Symptomatic fall in blood pressure when standing
6. Vascular claudication or pitting edema
7. Cognitive impairments that limit comprehension of protocol instructions (assessed by Comprehension Test of Consent Form)
8. Body weight over 150 kg
9. FES-I \< 25
10. Lower extremity injuries that limit range of motion or function
11. Joint problems (hip or leg) that limit range of motion or cause pain with movement
12. Unstable fractures
13. Pressure sores with any skin breakdown in areas in contact with the body harness or the robot-driven gait orthotic apparatus
14. Currently enrolled in an alcohol or drug treatment program
15. A complicating medical condition that would prevent completion of the trial
16. Enrolled in or planning to enroll in another interventional research trial using procedures proposed to enhance or limit the function of the upper or lower extremities (such as adjuvant rehabilitation or Botox injections) during the 24 weeks of participation
17. A difference of more than 2cm between subjects' right and left leg lengths
18. Unable to be properly fit into the harness or Lokomat device
19. Hypertonicity or spasticity that it interferes with a proper fit into the Lokomat
20. Pregnancy at enrollment, as determined by a home pregnancy test kit at screening visit
