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Clareo Health | Multiple Sclerosis Clinical Trials in Philadelphia | 137 Studies

Clinical Trials Multiple SclerosisPhiladelphia

Multiple Sclerosis Clinical Trials in Philadelphia

Find 137 clinical trials for multiple sclerosis near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Multiple Sclerosis trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 61-80 of 137 trials

Active not recruitingCentral Vein Sign: a Diagnostic Biomarker in Multiple SclerosisThe need for improved diagnostic methods in Multiple Sclerosis (MS) is widely recognized.NCT04495556·Los Angeles, California and 10 others CompletedA Study of Suboptimally Controlled Participants Previously Taking Oral or Infusion DMDs for RMS (MASTER-2)To evaluate the effectiveness, safety and Patient-Reported Outcomes (PROs) of cladribine tablets in participants with RMS including relapsing-remitting multiple sclerosis (RRMS)…NCT03933202·Cullman, Alabama and 65 others

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Data from ClinicalTrials.govTerms

UnknownOptic Neuritis Treatment Trial (ONTT)To assess the beneficial and adverse effects of corticosteroid treatment for optic neuritis. To determine the natural history of vision in patients who suffer optic neuritis.NCT00000146·Little Rock, Arkansas and 14 others

CompletedSafety and Tolerability of Conversion From Oral, Injectable, or Infusion Disease Modifying Therapies to Dose-titrated Oral Siponimod (Mayzent) in Advancing RMS PatientsTo assess safety and tolerability of patients converting from approved Relapsing Multiple Sclerosis (RMS) Disease Modifying Therapies (DMTs) to siponimod.NCT03623243·Birmingham, Alabama and 54 others

CompletedCladribine Tablets: Collaborative Study to Evaluate Impact On Central Nervous System Biomarkers in Multiple SclerosisThe purpose of this study is to better understand the mechanism of action (MoA) of cladribine tablets by exploring the effect on central nervous system (CNS) and blood biomarkers…NCT03963375·St Louis, Missouri and 4 others

CompletedA Study to Assess the Safety and Efficacy of Elezanumab When Added to Standard of Care in Relapsing Forms of Multiple SclerosisThe purpose of this study is to evaluate the safety and efficacy of elezanumab in participants with relapsing Multiple Sclerosis (RMS).NCT03737851·Birmingham, Alabama and 48 others

CompletedA Phase 2 Study of Cladribine Add-on to Interferon-beta (IFN-beta) Therapy in Multiple Sclerosis (MS) Subjects With Active Disease (ONWARD)The goal of this study was to evaluate the safety, tolerability and effectiveness of oral cladribine when taken in combination with Interferon-beta (IFN-beta) therapy for the…NCT00436826·Cullman, Alabama and 38 others

Active not recruitingEfficacy and Safety of Ofatumumab and Siponimod Compared to Fingolimod in Pediatric Patients With Multiple SclerosisEfficacy and safety of ofatumumab and siponimod compared to fingolimod in pediatric patients with multiple sclerosisNCT04926818·Little Rock, Arkansas and 50 others

CompletedSafety and Efficacy of Natalizumab in Combination With Avonex in the Treatment of Multiple SclerosisThe purpose of this study is to determine if natalizumab in combination with AVONEX is safe and effective in delaying progression of individuals diagnosed with relapsing remitting…NCT00030966·Birmingham, Alabama and 87 others

RecruitingA Study to Evaluate the Efficacy, Safety and Tolerability of BMS-986368 in Participants With Multiple Sclerosis SpasticityThe purpose of this study is to evaluate the efficacy, safety, and tolerability of BMS-986368 in participants with Multiple Sclerosis SpasticityNCT06782490·Birmingham, Alabama and 54 others

CompletedEfficacy and Safety Study of Oral BG00012 With Active Reference in Relapsing-Remitting Multiple SclerosisTo determine if treatment with BG00012 can decrease the number of MS relapses during a certain time period.NCT00451451·Birmingham, Alabama and 194 others

CompletedBEYOND Follow-up: Betaferon®/Betaseron® Efficacy Yielding Outcomes of a New DoseThe BEYOND Follow-Up study will give patients who participated in the preceding BEYOND study the opportunity to continue treatment with the 500µg dose of interferon beta (IFNB) 1b…NCT00459667·Birmingham, Alabama and 183 others

Active not recruitingATOMIC (Active Teens Multiple Sclerosis) Physical Activity Research ProgramThe investigators have previously shown that youth with MS are very inactive, and that vigorous physical activity is associated with higher levels of well-being and lower MS…NCT04782466·Birmingham, Alabama and 2 others

CompletedEnvironmental and Genetic Risk Factors for Pediatric Multiple SclerosisThe purpose of this study is to better understand multiple sclerosis (MS) in children and adolescents, to learn if it differs from adult MS and to investigate if genes or…NCT01396343·Birmingham, Alabama and 16 others

CompletedOptical Coherence Tomography (OCT) Trial in Multiple SclerosisThis is a 3-year, pharmacologically non-interventional study to evaluate OCT as an outcome measure in patients with relapsing remitting multiple sclerosis (RRMS).NCT02907281·San Francisco, California and 27 others

CompletedStudy of Tcelna (Imilecleucel-T) in Secondary Progressive Multiple SclerosisThe purpose of this study is to determine whether Tcelna (imilecleucel-T, autologous T-Cell Immunotherapy) is effective in the treatment of secondary progressive multiple…NCT01684761·Phoenix, Arizona and 35 others

CompletedPrimary Progressive Multiple Sclerosis (PPMS) Study of Bruton's Tyrosine Kinase (BTK) Inhibitor Tolebrutinib (SAR442168) (PERSEUS)Primary Objective: To determine the efficacy of SAR442168 compared to placebo in delaying disability progression in primary progressive multiple sclerosis (PPMS) Secondary…NCT04458051·La Jolla, California and 276 others

CompletedBEYOND: Betaferon/Betaseron Efficacy Yielding Outcomes of a New Dose in Multiple Sclerosis (MS) PatientsThe purpose of this study is to determine * whether treatment with Betaferon / Betaseron (interferon beta-1b) 500 micrograms safe, tolerable and more efficacious than treatment…NCT00099502·Birmingham, Alabama and 198 others

CompletedEfficacy and Safety of Fingolimod (FTY720) in Patients With Relapsing-remitting Multiple SclerosisThis study assessed the safety, tolerability and efficacy of two doses of oral fingolimod compared to placebo on efficacy parameters in patients with relapsing-remitting multiple…NCT00355134·Birmingham, Alabama and 111 others

CompletedThe Use of Arabic Otago Exercise Program in People With Multiple SclerosisPeople with multiple sclerosis (MS) need exercise training programs throughout their life in order to prevent secondary complications of the disease.NCT04818008·Amman

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