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Clinical TrialsMigraine

Migraine Clinical Trials

Browse 1,830 clinical trials for migraine. Find studies that match your criteria and connect with research centers.

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Showing 241-260 of 1,830 trials

CompletedPatient Reported Outcomes in Patients With Chronic Migraine Treated With BOTOX®This study will prospectively assess long term heath related quality of life in chronic migraine patients currently being treated with OnabotulinumtoxinA for injection (BOTOX®) as…NCT02502123·Calgary, Alberta and 14 others UnknownCortical Reorganisation in Patients With Primary Headache DisordersPrimary headache disorders are now accepted as physiological diseases, and advanced imaging-techniques have demonstrated a migraine generator in the brain stem and increased…NCT00263991·Glostrup, Copenhagen CompletedSafety, Tolerability and Drug- Drug Interaction Study of Ubrogepant With Erenumab or Galcanezumab in Participants With MigraineThis study will evaluate the potential for a pharmacokinetic (PK) interaction and provide safety and tolerability information when ubrogepant and erenumab or ubrogepant and…NCT04179474·Springfield, Missouri and 1 other

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Data from ClinicalTrials.govTerms

Active not recruitingA Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in AdultsA migraine is a headache with severe throbbing pain or a pulsating sensation, usually on one side of the head.NCT06625060·Birmingham, Alabama and 161 others

CompletedStructural and Molecular Neuroplasticity in MigraineThe main purpose of this study is to integrate novel MRI techniques with positron emission tomography(PET) for the study of structural and molecular neuroplasticity in the brain…NCT03004313·Ann Arbor, Michigan

UnknownPrecutaneous High Risk Patent Foramen Ovale to Treat Migraine HeadachesThe foramen ovale, a kind of physiologic channel in the interatrial septum in the heart at embryonic stage, is closed normally at 5-7 months after birth.NCT02777359·Xi'an, Shaanxi

RecruitingGreater Occipital Nerve Block for Migraine With Medication Overuse HeadacheMigraine is among the leading causes of disability worldwide.NCT07568496·Bangkok, Bangkok and 2 others

CompletedEP4-receptor Antagonism and Prostaglandin E2 (PGE2) in a Human Headache ModelThe purpose of this study is to determine whether EP-4 receptor antagonist can prevent the headache expected during a Prostaglandin E2 infusion.NCT00957983·Glostrup Municipality

CompletedTREXIMET® Versus Butalbital-containing Combination Medications for the Acute Treatment of Migraine in AdultsStudy TRX109011/TRX109013, A Randomized, Double-blind, Double-dummy, Placebo-controlled, Crossover Study to Evaluate the Efficacy of TREXIMET® (Sumatriptan + Naproxen Sodium)…NCT00573170·Chandler, Arizona and 106 others

CompletedBiomarker and Genetic Predictors of Erenumab Treatment ResponseTo explore the relationship between clinical response to erenumab and genetic biomarkersNCT04265755·Glostrup Municipality and 1 other

RecruitingDetermining the Utility of a Behavioral Intervention in Chronic MigraineThis proposal will involve a pilot study to evaluate the feasibility, acceptability, and outcomes of a lifestyle behavior protocol in managing chronic migraine.NCT05415020·Phoenix, Arizona

CompletedEvaluation of the Prophylactic Efficacy of tDCS in Chronic MigraineThe purpose of this study is to determine whether TDCS is an effective prophylactic therapy of chronic migraine.NCT02120326·Grenoble, Isere and 1 other

RecruitingA Study to Assess the Efficacy and Safety of Elismetrep (K-304) in the Acute Treatment of MigraineThis is a double-blind, randomized, multicenter, outpatient evaluation of the safety and efficacy of elismetrep, as compared with placebo, in the treatment of moderate or severe…NCT07816367·Glendale, Arizona and 71 others

CompletedEfficacy and Safety of Nerivio™ for Acute Treatment of Migraine in People With Chronic MigraineThis study is intended to evaluate the efficacy and safety of Nerivio, an FDA-authorized remote electrical neuromodulation (REN) device for the acute treatment of migraine, for…NCT04161807·Lagrangeville, New York and 1 other

CompletedA Dose-finding Trial With Lu-AG09222 in Adults With Migraine Who Have Not Been Helped by Prior Preventive TreatmentsThe purpose of this trial is to determine which doses of Lu AG09222 are recommended to help prevent migraines.NCT06323928·Hoover, Alabama and 119 others

RecruitingMechanistic Studies of Psilocybin in Headache DisordersIn previous clinical trial work, the investigators observed lasting reductions in headache burden after limited dosing of psilocybin.NCT06464367·West Haven, Connecticut

CompletedMechanism-based Choice of Therapy for Pain: Can Successful Prevention of Migraine be Coupled to a Psychophysical Pain Modulation Profile?Mechanism-based choice of therapy for pain: Can successful prevention of migraine be coupled to a psychophysical pain modulation profile?NCT01161017·Haifa

RecruitingPERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENSITIZATION IN HEADACHEHeadache, in its episodic and chronic forms, cannot be considered solely as an isolated neurological symptom, but as a complex condition of a bio-psycho-social nature.NCT07268768·Messina, Sicily

CompletedAn Exploratory Prospective Trial of Rescue Acupuncture for the Treatment of Acute MigraineThis will be an exploratory observational trial of rescue acupuncture for the treatment of acute migraine in military beneficiaries to gain information to inform the power…NCT02764996·Nellis Air Force Base, Nevada

CompletedBotulinum Toxin Type A Blockade of the Sphenopalatine Ganglion in Treatment-refractory Chronic MigraineThis is a clinical trial to assess the efficacy of botox treatment of the sphenopalatine ganglion as an add-on treatment in drug resistant migraine.NCT04069897·Bergen and 3 others

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