Migraine Clinical Trials

Showing 221-240 of 467 trials

Hypersensitivity to Opening of BKCa Channels in Post-Traumatic Headache

NCT05378074

The aim is to investigate whether opening of large conductance calcium-activated potassium (BKCa) channels induces headache with migraine-like features in people with persistent post-traumatic headache (PTH) attributed to mild traumatic brain injury (mTBI).

Post-Traumatic Headache

Danish Headache Center21 participantsStarted Sep 2022

Copenhagen, Denmark

COMPLETEDPHASE1

Sofusa System With Sumatriptan (KC5010) Phase 1 Dose Escalation Safety and PK Study (KCC-SMT-002)

NCT03229798

Study KCC-SMT-002, is a Phase 1, single-site, open-label, non-randomized, crossover, flexible dose design study to investigate the pharmacokinetic (PK) and safety comparing the Sofusa™ system with sumatriptan (KC5010) to Imitrex® oral tablets in 17 healthy volunteers.

Migraine Disorders

Sorrento Therapeutics, Inc.19 participantsStarted Jan 2018

Raleigh, North Carolina, United States

UNKNOWN

Validity of Headache Disability Index

NCT05376163

The aim of our study is to investigate the Turkish validity and reliability of The Henry Ford Hospital Headache Disability Questionnaire (HDI), which has not been previously studied in a Turkish version for any headache type in patients with cervicogenic headache.

Neck PainHeadacheCervical Pain

Hacettepe University250 participantsStarted Sep 2022

Ankara, Turkey (Türkiye)

COMPLETEDNA

Physiological Changes With SPG Stimulation in Migraine Patients

NCT02510742

Hypothesis: Stimulation of the SPG at low frequencies (20 Hz)is believed to cause a physiological parasympathetic upregulation which increases VMCA, concentration and cephalic vessel diameter.

Chronic Migraine

Danish Headache Center12 participantsStarted Jul 2015

Copenhagen, Glostrup, Denmark

Hypersensitivity to Opening of BKCa Channels in Post-Traumatic Headache

Sofusa System With Sumatriptan (KC5010) Phase 1 Dose Escalation Safety and PK Study (KCC-SMT-002)

Validity of Headache Disability Index

Physiological Changes With SPG Stimulation in Migraine Patients

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Effect of Erenumab-aooe on Disability and Work Productivity in Employed Subjects With Episodic Migraine

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Bupivacaine for Benign Headache in the ED

The Effect of Topiramate on Etonogestrel Concentrations in Contraceptive Implant Users

RELAXaHEAD for Headache Patients (Phase I)

Hypersensitivity to Opening of ATP-Sensitive Potassium Channels in Post-Traumatic Headache

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Study To Assess Adverse Events and Drug to Drug Interaction of Oral Tablet Atogepant and Ubrogepant in Adult Participants With a History of Migraine

Effect of Small Versus Large Epidural Needles on Postdural Puncture Headache Study

KETOMIGRAINE: Ketogenic Diet in Drug-resistant Chronic Migraineurs

Saline Injections for Prophylactic Treatment of Chronic Migraine

Predictive Score for Non-traumatic Secondary Headache After an Emergency Call

A Study Evaluating the Effectiveness of AMG 334 Injection in Preventing Migraines in Adults Having Failed Other Therapies