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Clareo Health | Melanoma Clinical Trials | 3,344 Studies Recruiting

Clinical TrialsMelanoma

Melanoma Clinical Trials

Browse 3,344 clinical trials for melanoma. Find studies that match your criteria and connect with research centers.

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Showing 2021-2040 of 3,344 trials

CompletedInterleukin-21 in Treating Patients With Metastatic or Recurrent Malignant MelanomaRATIONALE: Interleukin-21 may stimulate white blood cells, including natural killer cells, to kill melanoma cells.NCT00514085·Edmonton, Alberta and 6 others CompletedSorafenib and Isolated Limb Infusion of Melphalan in Treating Patients With Stage III Melanoma of the Arm or LegRATIONALE: Sorafenib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth and by blocking blood flow to the tumor.NCT00565968·New York, New York TerminatedNiraparib in the Treatment of Patients With Advanced PALB2 Mutated TumorsThe purpose of this study is to further evaluate the efficacy and safety of niraparib in patients with locally advanced or metastatic solid tumors and a pathogenic or likely…NCT05169437·Yuma, Arizona and 79 others

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Data from ClinicalTrials.govTerms

RecruitingEfficacy And Safety Of Anti-PD-1/PD-L1 Antibodies In Combination With Bevacizumab And Metronomic Cyclophosphamide In Patients With Non-Small Cell Lung Cancer And Cutaneous Melanoma Previously Treated With Immune Checkpoint BlockadeThis study will evaluate efficacy and safety of anti-PD-1/PD-L1 antibodies combined with bevacizumab and metronomic cyclophosphamide in patients with metastatic non-small cell…NCT07130032·Saint Petersburg, Sankt-Peterburg

CompletedSubstudy 02D: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents or Pembrolizumab Alone in Participants With Melanoma Brain Metastasis (MK-3475-02D/KEYMAKER-U02)Substudy 02D is part of a larger research study that is testing experimental treatments for melanoma, a type of skin cancer. The larger study is the umbrella study.NCT04700072·Los Angeles, California and 35 others

CompletedEffects of Dabrafenib on the Single Dose Pharmacokinetics (PK) of Rosuvastatin and MidazolamThis is an open-label, multi-center, fixed sequence study in subjects with BRAF V600 mutation positive tumors.NCT02082665·Lebanon, New Hampshire and 3 others

CompletedVaccine Therapy in Treating Patients With Metastatic MelanomaRATIONALE: Vaccines made from a person's white blood cells and melanoma cells may make the body build an immune response and kill tumor cells.NCT00003792·Dallas, Texas

RecruitingHigh-Intensity Exercise and High-Fiber Diet for Immunotherapy Outcomes in Melanoma Patients: The DUO TrialThe purpose of this study is to determine whether high-intensity exercise and high-fiber diet are feasible and improve various health outcomes among participants with advanced…NCT06298734·Boston, Massachusetts and 1 other

UnknownPV-10 in Combination With Pembrolizumab for Treatment of Metastatic MelanomaThis is an international multicenter, open-label, sequential phase study of intralesional (IL) PV-10 in combination with immune checkpoint inhibition.NCT02557321·Tampa, Florida and 4 others

CompletedPositron Emission Tomography and CT Scan in Predicting Response in Patients With Metastatic Melanoma or Kidney Cancer Who Are Undergoing Cellular Adoptive Immunotherapy on a Surgery Branch Clinical TrialRATIONALE: Diagnostic procedures, such as positron emission tomography and computed tomography scan (done before and after cellular adoptive immunotherapy), may help doctors…NCT00316901·Bethesda, Maryland

CompletedImmunization With Autologous Dendritic Cells and Tumor Lysates in Melanoma PatientsImplementing this protocol has its ethical justification in that patients with metastatic melanoma, once tumor invasion has reached beyond the lymph node barrier, cannot possibly…NCT06152367·Santiago, RM

CompletedA Study of Tasisulam in Treating Participants With Malignant MelanomaThe primary purpose of this study is to determine the objective response rate (complete and partial response) for participants who receive tasisulam after one prior systemic…NCT00383292·Los Angeles, California and 12 others

TerminatedKZR-261 in Subjects With Advanced Solid MalignanciesA first-in-human, open-label, multicenter, Phase 1 study of KZR-261 designed to assess the safety and tolerability, preliminary anti-tumor activity, and pharmacokinetics (PK) of…NCT05047536·Los Angeles, California and 11 others

TerminatedA Study of MEK162 and AMG 479 in Patients With Selected Solid TumorsThis is a multi-center, open-label, phase Ib/II study.NCT01562899·Boston, Massachusetts and 8 others

CompletedDetermine Toxicity and Antibody Responses With a KLH Conjugated Bivalent Vaccine Containing GD2 Lactone, GD3 Lactone With Immunological Adjuvant QS-DG or OPT-821 in Patients With Disease Free AJCC Stage III or IV Cutaneous MelanomaVaccines contain substances that help us make antibodies. Different antibodies help protect us against a variety of harmful things.NCT00597272·New York, New York

CompletedRAD001 Plus Bevacizumab in Metastatic MelanomaThis is a non-randomized, open label Phase II study comparing bevacizumab and everolimus in the treatment of metastatic melanoma.NCT00591734·Fort Myers, Florida and 14 others

Not yet recruitingEvaluating a Decision Aid for Sentinel Lymph Node Biopsy in Intermediate-Risk MelanomaThis research study is testing a decision aid to help patients think through whether to have sentinel lymph node biopsy for melanoma.NCT07653087·Charlottesville, Virginia

WithdrawnSargramostim or Hypertonic Saline Before Sentinel Lymph Node Biopsy in Treating Patients With Stage IB-II MelanomaThis randomized phase III trial studies sargramostim before sentinel lymph node biopsy to see how well it works compared to hypertonic saline before sentinel lymph node biopsy in…NCT01826864·Los Angeles, California

CompletedADI-PEG in Patients With Metastatic MelanomaThis is a study to determine the safety and toxicity of increasing doses of arginine deiminase combined to polyethylene glycol (ADI-PEG) in patients with nonresectable metastatic…NCT00029900·Chicago, Illinois

CompletedPhase 1 Study of MPC-6827 and Temozolomide in Metastatic MelanomaThis is an open-label, dose finding, multiple-dose study in subjects with metastatic melanoma.NCT00609011·Los Angeles, California and 4 others

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