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Clareo Health | Melanoma Clinical Trials in Pennsylvania | 460 Studies

Clinical Trials MelanomaPennsylvania

Melanoma Clinical Trials in Pennsylvania

Find 460 clinical trials for melanoma near Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 161-180 of 460 trials

CompletedVaccine Therapy With High-Dose Interleukin-2 in Treating Patients With Metastatic MelanomaRATIONALE: Vaccines may make the body build an immune response that will kill tumor cells. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells.NCT00003568·Duarte, California and 8 others TerminatedA Phase I/II Study of GMX1777 in Combination With Temozolomide for the Treatment of Metastatic MelanomaObatoclax Mesylate (GMX1777) is a water-soluble, intravenously-administered pro-drug of GMX1778. GMX1777 is rapidly converted to GMX1778 in vivo.NCT00724841·Philadelphia, Pennsylvania TerminatedStudy of Temzolomide and Gleevec in Advanced MelanomaThis study has been designed to evaluate the side effects of Gleevec when given in combination with Temzolomide; and to learn more about how these drugs work in the body and…NCT00667953·Philadelphia, Pennsylvania TerminatedStudy of Motexafin Gadolinium With Whole Brain Radiation Therapy Followed by Stereotactic Radiosurgery Boost in the Treatment of Patients With Brain MetastasesThe primary purpose of the study is to evaluate if motexafin gadolinium with whole brain radiation therapy followed by a stereotactic radiosurgery boost is a safe and effective…NCT00121420·Phoenix, Arizona and 11 others

Melanoma Trials in Other Cities

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Data from ClinicalTrials.govTerms

TerminatedA Study of Varlilumab (Anti-CD27) and Ipilimumab and CDX-1401 in Patients With Unresectable Stage III or IV MelanomaThis is a study to determine the clinical benefit (how well the drug works), safety and tolerability of combining a) varlilumab and ipilimumab and b) varlilumab, ipilimumab…NCT02413827·San Francisco, California and 7 others

CompletedStudy to Determine the Effectiveness of GSK1120212 in BRAF Mutation-positive Melanoma Previously Treated With or Without a BRAF InhibitorMEK113583 is a Phase II open-label, multi-site study to investigate the objective response rate, safety, and pharmacokinetics of GSK1120212 in subjects with BRAF mutation-positive…NCT01037127·Los Angeles, California and 9 others

CompletedStudy to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the BrainThis is a multi-cohort, open label, Phase II study with Dabrafenib (GSK2118436) and Trametinib (GSK1120212) combination therapy in subject with BRAF mutation-positive melanoma…NCT02039947·Birmingham, Alabama and 46 others

No longer availableExpanded Access Program With Nivolumab in Combination With Ipilimumab in Patients With Tumors Unable to be Removed by Surgery or Metastatic MelanomaThe purpose of this study is to provide treatment with nivolumab in combination with ipilimumab to subjects who are anti-(CTLA)-4 and anti-PD-1 treatment-naive and have…NCT02186249·Gilbert, Arizona and 65 others

CompletedStudy of the CD40 Agonistic Monoclonal Antibody APX005MThis study is a phase 1 open-label dose escalation study of the immuno-activating monoclonal antibody APX005M in adults with solid tumors.NCT02482168·Duarte, California and 2 others

CompletedAn Open-Label, 2-Cohort, Multicenter, Study of Lenvatinib in Previously Treated Subjects With Unresectable Stage III or Stage IV MelanomaThe purpose of this study is to assess the objective response rate of lenvatinib in previously treated participants with American Joint Committee on Cancer (AJCC) unresectable…NCT01136967·Birmingham, Alabama and 94 others

CompletedA Study of IMC-1121B (Ramucirumab) With or Without Dacarbazine in Metastatic Malignant MelanomaThe primary objective of this study is to determine the progression-free survival (PFS) of participants with previously untreated metastatic malignant melanoma when treated with…NCT00533702·Decatur, Alabama and 16 others

TerminatedStage IV Surgery Versus Best Medical TherapyThis study will establish the role of surgical versus nonsurgical approaches in patients whose melanoma has spread to distant sites.NCT01013623·Sacramento, California and 18 others

Active not recruitingA First-in-human Study to Learn How Safe the Study Drug BAY2965501 is, Find the Best Dose (Single Drug & Combination), How it Affects the Body, What Maximum Amount Can be Given, How it Moves Into, Through and Out of the Body, How it Acts on Different Tumors in Participants With Advanced Solid TumorsResearchers are looking for a better way to treat people who have advanced solid tumors.NCT05614102·Denver, Colorado and 20 others

CompletedTrial of Dacarbazine With or Without Genasense in Advanced MelanomaThis study is being performed to prospectively determine whether dacarbazine plus Genasense is significantly better than dacarbazine plus placebo in chemotherapy-naive patients…NCT00518895·Mobile, Alabama and 76 others

Active not recruitingNBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 TherapyThe 1100 study is an open-label, Phase I, dose escalation and expansion prospective clinical study to assess the safety of intratumoral injection of NBTXR3 activated by…NCT03589339·San Francisco, California and 12 others

CompletedCarboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by SurgeryThis randomized phase III trial studies carboplatin, paclitaxel, and sorafenib tosylate to see how well they work compared to carboplatin and paclitaxel in treating patients with…NCT00110019·Birmingham, Alabama and 218 others

CompletedA Study Comparing Trametinib and Dabrafenib Combination Therapy to Dabrafenib Monotherapy in Subjects With BRAF-mutant MelanomaThis was a two-arm, double-blinded, randomized, Phase III study comparing dabrafenib and trametinib combination therapy to dabrafenib administered with a placebo (dabrafenib…NCT01584648·Scottsdale, Arizona and 120 others

CompletedTailored Intervention for Melanoma Patient's FamiliesThe purpose of the investigators' study is to find the best way to provide information about sun protection and skin cancer detection.NCT00816374·Tampa, Florida and 2 others

CompletedTretinoin With or Without Fenretinide in Treating Patients With Dysplastic Nevus SyndromeRATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer.NCT00003601·Philadelphia, Pennsylvania

CompletedMulticenter Selective Lymphadenectomy Trial II (MSLT-II)Subjects must be diagnosed with melanoma. All subjects receive sentinel lymphadenectomy.NCT00297895·San Diego, California and 62 others

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