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Clareo Health | Melanoma Clinical Trials in Pennsylvania | 457 Studies

Clinical Trials MelanomaPennsylvania

Melanoma Clinical Trials in Pennsylvania

Find 457 clinical trials for melanoma near Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 81-100 of 457 trials

CompletedMelanoma Molecular Profiling AnalysisThere is a significant need to develop new and more effective ways to treat melanoma that will decrease patient morbidity and mortality.NCT00889980·Pittsburgh, Pennsylvania RecruitingPatient Preference for Subcutaneous vs. Intravenous Immune TherapyThe study will evaluate patient and Health Care Professional- reported preference for Subcutaneous (SC) compared with IV nivolumab administration or similarly for SC compared with…NCT07223424·Pittsburgh, Pennsylvania TerminatedPV-10 vs Chemotherapy or Oncolytic Viral Therapy for Treatment of Locally Advanced Cutaneous MelanomaThis is an international multicenter, open-label, randomized controlled trial (RCT) of single-agent intralesional PV-10 versus systemic chemotherapy or intralesional oncolytic…NCT02288897·San Diego, California and 22 others

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Data from ClinicalTrials.govTerms

Active not recruitingTargeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)This phase II MATCH screening and multi-sub-trial studies how well treatment that is directed by genetic testing works in patients with solid tumors, lymphomas, or multiple…NCT02465060·Birmingham, Alabama and 1409 others

CompletedCarboplatin and ABI-007 in Treating Patients With Stage IV Melanoma That Cannot Be Removed By SurgeryRATIONALE: Drugs used in chemotherapy, such as carboplatin and ABI-007, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them…NCT00404235·Scottsdale, Arizona and 155 others

TerminatedA Phase 1a/1b Study of ACTM-838 in Patients With Advanced Solid TumorsThis is a first in human (FIH) 2-part study using ACTM-838 in patients with advanced solid tumors resistant to standard of care treatment.NCT06336148·Los Angeles, California and 4 others

CompletedA Study of Combination Treatment With HF10 and Ipilimumab in Patients With Unresectable or Metastatic MelanomaThe purpose of this study is to determine if HF10 in combination with ipilimumab is effective in patients with stages IIIB, IIIC, or IV unresectable or metastatic melanoma.NCT02272855·San Francisco, California and 7 others

Active not recruitingA Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid TumorsThis study aims to assess the safety, tolerability, pharmacokinetics, and preliminary efficacy of APG-115, an MDM2 inhibitor, either alone or in combination with pembrolizumab, a…NCT03611868·Tucson, Arizona and 20 others

CompletedStudy of VE800 and Nivolumab in Patients With Selected Types of Advanced or Metastatic CancerThis study evaluated the safety and efficacy of VE800 in combination with nivolumab in patients with selected types of advanced or metastatic cancerNCT04208958·Scottsdale, Arizona and 17 others

CompletedChemotherapy With or Without Immunotherapy in Treating Patients With Stage III or Stage IV MelanomaRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003647·Little Rock, Arkansas and 43 others

CompletedPhase IIB TL + YCWP + DC in MelanomaThe majority of melanoma vaccines tested to date have been antigen-specific vaccines targeting melanoma-specific or associated antigens and utilizing a variety of delivery systems…NCT02301611·Birmingham, Alabama and 17 others

CompletedStudy of CP-675,206 in Refractory MelanomaCP-675,206 is a fully human monoclonal antibody (mAb). It binds to the CTLA4 molecule, which is expressed on the surface of activated T lymphocytes.NCT00254579·Scottsdale, Arizona and 64 others

CompletedPilot Study Evaluating Sulforaphane in Atypical Nevi-Precursor LesionsThis is a pilot study to see if oral administration of freeze dried, powdered broccoli sprouts have any effect on whether moles end up becoming melanoma.NCT01568996·Pittsburgh, Pennsylvania

RecruitingA First-In Human (FIH) Study to Find Out How Well REGN10597 Medicine Given Alone or in Combination With Cemiplimab Works in Adult Participants Who Have Cancer With Tumors That Have Spread in Their BodyThis study is researching an experimental drug called REGN10597 alone or in combination with another drug called cemiplimab (called "study drug(s)").NCT06413680·Los Angeles, California and 10 others

CompletedStudy of TLR9 Agonist Vidutolimod (CMP-001) in Combination With Nivolumab vs. NivolumabThe main goal of this research study is to determine how nivolumab and nivolumab/Vidutolimod (CMP-001) combination affect the likelihood of destroying melanoma involving lymph…NCT04401995·Pittsburgh, Pennsylvania

Active not recruitingVeliparib, Paclitaxel, and Carboplatin in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by Surgery and Liver or Kidney DysfunctionThis phase I trial studies the side effects and the best dose of veliparib when given together with paclitaxel and carboplatin in treating patients with solid tumors that are…NCT01366144·Duarte, California and 16 others

CompletedPhase 2 Study of Intralesional PV-10 for Metastatic MelanomaThe primary objective of this study is to investigate the effectiveness of intralesional (IL) PV-10 for locoregional treatment of metastatic melanoma.NCT00521053·San Francisco, California and 6 others

AvailableExpanded Access to Ulixertinib (BVD-523) in Patients With Advanced MAPK Pathway-Altered MalignanciesThe objective of this expanded access program is to provide ulixertinib (BVD-523) for compassionate use in advanced cancer patients with MAPK pathway-altered solid tumor(s)…NCT04566393·Mobile, Alabama and 25 others

CompletedLUMINOS-102: Lerapolturev With or Without Immune Checkpoint Blockade in Advanced PD-1 Refractory MelanomaA Phase 2 study to investigate the efficacy and safety of lerapolturev alone or in combination with a programmed death receptor-1 (anti-PD-1) inhibitor.NCT04577807·Scottsdale, Arizona and 11 others

RecruitingAssessing Benefits and Harms of Cannabis/Cannabinoid Use Among Cancer Patients Treated in Community Oncology ClinicsThis is a multi-site clinical study enrolling 2000 newly diagnosed patients with breast, colorectal, melanoma, non-Hodgkin lymphoma, or non-small cell lung cancer, who are…NCT06418204·Fairbanks, Alaska and 466 others

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Other Conditions in Pennsylvania

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma