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Clareo Health | Melanoma Clinical Trials in Pennsylvania | 460 Studies

Clinical Trials MelanomaPennsylvania

Melanoma Clinical Trials in Pennsylvania

Find 460 clinical trials for melanoma near Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pennsylvania

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 61-80 of 460 trials

CompletedSafety and Efficacy of SB 11285 Alone and in Combination With Atezolizumab in Patients With Advanced Solid TumorsA Phase 1a/1b, multicenter, open-label, non-randomized, dose-escalation, and cohort expansion study to examine the DLTs, MTD, and RP2D of SB 11285 administered as an IV infusion…NCT04096638·Philadelphia, Pennsylvania and 1 other Active not recruitingGEN1042 Safety Trial and Anti-tumor Activity in Participants With Malignant Solid TumorsThe goal of this trial is to learn about the antibody GEN1042 when it is used alone and when it is used together with another antibody cancer drug, pembrolizumab (with or without…NCT04083599·Anchorage, Alaska and 75 others

Melanoma Trials in Other Cities

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Data from ClinicalTrials.govTerms

CompletedIpilimumab With or Without High-Dose Recombinant Interferon Alfa-2b in Treating Patients With Stage III-IV Melanoma That Cannot Be Removed by SurgeryThis randomized phase II trial studies how well ipilimumab with or without high-dose recombinant interferon alpha-2b works in treating patients with stage III-IV melanoma that…NCT01708941·Birmingham, Alabama and 275 others

CompletedIpilimumab vs Ipilimumab Plus Nivolumab in Patients With Stage III-IV Melanoma Who Have Progressed or Relapsed on PD-1 Inhibitor TherapyThe purpose of this research study is to learn whether patients whose disease grows after being treated with nivolumab or pembrolizumab respond to ipilimumab (Yervoy®) alone or in…NCT02731729·Los Angeles, California and 6 others

WithdrawnStudy of Neoadjuvant Imprime PGG and Pembrolizumab for Stage III, Resectable MelanomaApproximately 50 ABA+ subjects with resectable, Stage III (IIIB, IIIC, or IIID) melanoma will be included in the study and randomized in a 3:2 ratio to neoadjuvant treatment with…NCT04995094·La Jolla, California and 3 others

TerminatedA Study of Modakafusp Alfa (TAK-573) Given by Itself and Together With Pembrolizumab in Adults With Advanced or Metastatic Solid TumorsThis study has 2 phases. The main aims of Phase 1b are: * to check for side effects from modakafusp alfa in adults with locally advanced or metastatic solid tumors.NCT04157517·Duarte, California and 16 others

CompletedDasatinib in Treating Patients With Locally Advanced or Metastatic Mucosal Melanoma, Acral Melanoma, or Vulvovaginal Melanoma That Cannot Be Removed By SurgeryRATIONALE: Dasatinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00700882·Little Rock, Arkansas and 152 others

CompletedPhase 1/2 Study Exploring the Safety, Tolerability, and Efficacy of INCAGN01876 Combined With Immune Therapies in Advanced or Metastatic MalignanciesThe purpose of this study is to determine the safety, tolerability, and efficacy of INCAGN01876 when given in combination with immune therapies in subjects with advanced or…NCT03126110·Los Angeles, California and 37 others

TerminatedPhase I Safety and Dosimetry Study in Patients With Confirmed Metastatic MelanomaThis is an open-label, single dose study for patients 18 years of age or older with confirmed metastatic melanoma.NCT00747825·Philadelphia, Pennsylvania

CompletedUV1 Vaccine With Pembrolizumab for Patients With Unresectable or Metastatic MelanomaUV1 is a therapeutic cancer vaccine that has been explored in prostate and lung cancers, and in combination with ipilimumab in malignant melanoma.NCT03538314·Santa Monica, California and 3 others

TerminatedNM32-2668 in Adult Patients With Selected Advanced Solid TumorsThis is a first-in-human, open-label, multi-center, Phase 1, dose-escalation study with expansion cohorts to evaluate NM32-2668 for safety and immunogenicity, to determine the…NCT06299163·Birmingham, Alabama and 10 others

CompletedDose-escalation Study of Combination BMS-936558 (MDX-1106) and Ipilimumab in Subjects With Unresectable Stage III or Stage IV Malignant MelanomaThe purpose of this study is to determine the safety and tolerability of treatment with BMS-936558 (MDX-1106) in combination with Ipilimumab (BMS-734016) when given at the same…NCT01024231·New Haven, Connecticut and 3 others

Active not recruitingA Clinical Study of Intismeran Autogene (V940) Plus Pembrolizumab in People With High-Risk Melanoma (V940-001)The purpose of this study is to learn if intismeran autogene which is an individualized neoantigen therapy (INT; formerly, called messenger ribonucleic acid \[mRNA\]-4157) with…NCT05933577·Springdale, Arkansas and 164 others

Active not recruitingPhysician/Patient Choice of Either High-Dose Recombinant Interferon Alfa-2B or Ipilimumab, Versus Pembrolizumab in Treating Patients With Stage III-IV High Risk Melanoma That Has Been Removed by SurgeryThis randomized phase III trial studies how well pembrolizumab works compared with the current standard of care, physician/patient choice of either high-dose recombinant…NCT02506153·Birmingham, Alabama and 575 others

CompletedPhase 1 Study of GRN-1201 in HLA-A*02 Subjects With Resected MelanomaThis is a study of an investigational cancer vaccine called GRN-1201. Treatment with the GRN-1201 vaccine is a type of immunotherapy.NCT02696356·Cincinnati, Ohio and 3 others

CompletedModifying Young Adult Skin Cancer Risk and Protective BehaviorsSkin cancer is the most common cancer and can be deadly, debilitating, damaging, and disfiguring, yet is highly preventable.NCT03313492·New Brunswick, New Jersey and 1 other

TerminatedKZR-261 in Subjects With Advanced Solid MalignanciesA first-in-human, open-label, multicenter, Phase 1 study of KZR-261 designed to assess the safety and tolerability, preliminary anti-tumor activity, and pharmacokinetics (PK) of…NCT05047536·Los Angeles, California and 11 others

CompletedEfficacy and Safety Study of Talimogene Laherparepvec Compared to Granulocyte Macrophage Colony Stimulating Factor (GM-CSF) in MelanomaThe objective of this study is to evaluate the efficacy and safety of treatment with talimogene laherparepvec compared to subcutaneously administered GM-CSF in patients with…NCT00769704·Tucson, Arizona and 82 others

Active not recruitingEffectiveness Study of Nivolumab Compared to Placebo in Prevention of Recurrent Melanoma After Complete Resection of Stage IIB/C MelanomaThe purpose of this study is to determine the effectiveness of nivolumab adjuvant immunotherapy compared to placebo in adults and pediatric participants after complete resection…NCT04099251·Birmingham, Alabama and 129 others

Enrolling by invitationTruScore Standalone Clinical StudyThe goal of this clinical trial is to evaluate if the TruScore device can accurately diagnose suspicious skin lesions in patients aged 22 years and older.NCT06793423·Pleasanton, California and 5 others

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Other Conditions in Pennsylvania

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma