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Clareo Health | Melanoma Clinical Trials in Pennsylvania | 460 Studies

Clinical Trials MelanomaPennsylvania

Melanoma Clinical Trials in Pennsylvania

Find 460 clinical trials for melanoma near Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pennsylvania

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

Healthy volunteers too

Showing 421-440 of 460 trials

SuspendedPropranolol Hydrochloride and Pembrolizumab in Treating Patients With Stage IIIC-IV Melanoma That Cannot Be Removed by SurgeryThis phase Ib/II trial studies the side effects and best dose of propranolol hydrochloride when given together with pembrolizumab and how well they work in treating patients with…NCT03384836·Atlanta, Georgia and 3 others CompletedStudy to Compare Two Formulations of CP-675,206 Monoclonal AntibodyThis is an open-label, 2-arm study in which patients are randomized to receive either the formulation that is being used in clinical trials or the formulation that will be used…NCT00431275·Scottsdale, Arizona and 7 others RecruitingSafety and Efficacy of OBX-115 in Advanced Solid TumorsThis is a study to investigate the safety and efficacy of an investigational OBX-115 regimen in adult participants with advanced solid tumors.NCT06060613·Tucson, Arizona and 13 others

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Data from ClinicalTrials.govTerms

CompletedA Phase 3 Pivotal Trial Comparing Allovectin-7® Alone vs Chemotherapy Alone in Patients With Stage 3 or Stage 4 MelanomaTo compare the safety and efficacy of Allovectin-7® versus Dacarbazine (DTIC)or Temozolomide (TMZ) in subjects with recurrent stage 3 or stage 4 melanoma.NCT00395070·Tucson, Arizona and 87 others

CompletedImmunogenicity and Biomarker Analysis of Neoadjuvant Ipilimumab for MelanomaIpilimumab is a manufactured monoclonal antibody, much like the antibodies usually made by the human body to fight off infection; however it is not known why the human body does…NCT00972933·Pittsburgh, Pennsylvania

CompletedA Study of PRT1419 in Patients With Advanced Solid TumorsThis is a Phase 1 dose-escalation study of PRT1419, a myeloid cell leukemia 1 (MCL1) inhibitor, in patients with advanced solid tumors.NCT04837677·Denver, Colorado and 6 others

TerminatedHD IL-2 + Vemurafenib in Patients With BRAF Mutation Positive Metastatic MelanomaThis is a research study to evaluate treatment of metastatic melanoma patients with a combination of drugs.NCT01683188·Tucson, Arizona and 20 others

CompletedA Study to Evaluate RAF265, an Oral Drug Administered to Subjects With Locally Advanced or Metastatic MelanomaThe purpose of this study is to determine the safety profile, pharmacokinetics, pharmacodynamics and maximum tolerated dose of RAF265 in patients with locally advanced and…NCT00304525·Aurora, Colorado and 10 others

CompletedNivolumab in Treating Patients With Stage IIB-IIC Melanoma That Can Be Removed by SurgeryThis phase II trial studies how well nivolumab works in treating patients with stage IIB-IIC melanoma that can be removed by surgery.NCT03405155·New Brunswick, New Jersey and 3 others

RecruitingDESTINY-PANTUMOUR04This study will evaluate the effectiveness of T-DXd in patients with HER2-positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have received prior…NCT07124000·Birmingham, Alabama and 17 others

CompletedStudy of Nivolumab (BMS-936558) Plus Ipilimumab Compared With Ipilimumab Alone in the Treatment of Previously Untreated, Unresectable, or Metastatic MelanomaThe primary purpose of this study is to compare the objective response rate, as determined by investigators, of Nivolumab combined with Ipilimumab versus Ipilimumab monotherapy in…NCT01927419·San Francisco, California and 20 others

RecruitingStudy of CBL0137 in Combination With Ipilimumab and Nivolumab Therapy in MelanomaPhase I, open label, dose-escalation, and safety study designed to assess the safety and biologic activity of the investigational agent CBL0137 in combination with standard of…NCT05498792·Philadelphia, Pennsylvania

CompletedVaccine Therapy With or Without Sargramostim in Treating Patients With Stage IIB, Stage IIC, Stage III, or Stage IV MelanomaRATIONALE: Vaccines may make the body build an immune response to kill tumor cells.NCT00089193·Washington D.C., District of Columbia and 4 others

CompletedEvaluating The Antitumor Activity Of MEDI-522 With Or Without Dacarbazine In Patients With Metastatic MelanomaThe primary objectives of this study are: * To explore the antitumor activity of MEDI-522 ± DTIC in patients with metastatic melanoma.NCT00066196·Scottsdale, Arizona and 24 others

CompletedTemsirolimus and Bryostatin 1 in Treating Patients With Unresectable or Metastatic Solid TumorsThis phase I trial is studying the side effects and best dose of temsirolimus when given together with bryostatin 1 in treating patients with unresectable or metastatic solid…NCT00112476·Philadelphia, Pennsylvania

Active not recruitingMelmarT Melanoma Margins Trial Investigating 1cm v 2cm Wide Excision Margins for Primary Cutaneous MelanomaPatients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin.NCT02385214·Philadelphia, Pennsylvania and 19 others

CompletedMAGE-A10ᶜ⁷⁹⁶T for Urothelial Cancer, Melanoma or Head and Neck CancersThis Phase 1 study is designed as a cell dose escalation trial in HLA-A\*02:01 and HLA-A\*02:06 subjects with MAGE-A10 positive urothelial, melanoma or head and neck tumors.NCT02989064·Boston, Massachusetts and 10 others

CompletedImproving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVRImproving Adherence to Oral Cancer Agents and Self Care of Symptoms Using an IVR The goals of this study are to improve adherence to oral chemotherapeutic medications and…NCT02043184·New Haven, Connecticut and 7 others

CompletedA Clinical Trial of KVA12123 [TBS-2025] Treatment Alone and in Combination With Pembrolizumab In Advanced Solid Tumors (VISTA-101)This clinical trial evaluated the safety and efficacy of KVA12123, subsequently designated TBS-2025, alone or combined with pembrolizumab in patients with advanced solid tumors.NCT05708950·Santa Monica, California and 6 others

CompletedLUMINOS-102: Lerapolturev With or Without Immune Checkpoint Blockade in Advanced PD-1 Refractory MelanomaA Phase 2 study to investigate the efficacy and safety of lerapolturev alone or in combination with a programmed death receptor-1 (anti-PD-1) inhibitor.NCT04577807·Scottsdale, Arizona and 11 others

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