Nivolumab in Treating Patients With Stage IIB-IIC Melanoma That Can Be Removed by Surgery

PRIMARY OBJECTIVES: I. To assess the efficacy nivolumab administered in the adjuvant setting in patients with resected stage IIB or stage IIC cutaneous melanoma. SECONDARY OBJECTIVES: I. To evaluate and estimate the median duration of overall survival (OS) in stage IIB-IIC melanoma patients. II. To evaluate and estimate the median duration of distant metastases-free survival (DMFS) in stage IIB-IIC melanoma patients. III. To assess safety and toxicity using Common Terminology Criteria for Adverse Events (CTCAE) version (V)5. IV. To assess quality of life using the Functional Assessment of Cancer Therapy-Melanoma (FACT-M) quality of life instrument. TERTIARY OBJECTIVES: I. To assess and compare clinical, histological, immunological and molecular panels as prognostic and predictive biomarkers.