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Clareo Health | Melanoma Clinical Trials in Pennsylvania | 457 Studies

Clinical Trials MelanomaPennsylvania

Melanoma Clinical Trials in Pennsylvania

Find 457 clinical trials for melanoma near Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 381-400 of 457 trials

CompletedStudy of Aerosolized Sargramostim in Treating Patients With Melanoma Metastatic to the LungRATIONALE: Colony-stimulating factors, such as sargramostim, may help the body's immune system to kill cancer cells.NCT00005610·Scottsdale, Arizona and 17 others Active not recruitingIpilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by SurgeryThis randomized phase III trial studies ipilimumab to see how well it works compared to high-dose interferon alfa-2b in treating patients with high-risk stage III-IV melanoma that…NCT01274338·Birmingham, Alabama and 936 others

Melanoma Trials in Other Cities

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Data from ClinicalTrials.govTerms

CompletedVaccine Therapy With High-Dose Interleukin-2 in Treating Patients With Metastatic MelanomaRATIONALE: Vaccines may make the body build an immune response that will kill tumor cells. Interleukin-2 may stimulate a person's white blood cells to kill melanoma cells.NCT00003568·Duarte, California and 8 others

UnknownVaccine Therapy in Treating Patients With Malignant MelanomaRATIONALE: Vaccines made from tumor cells may help the body build an effective immune response to kill tumor cells.NCT00128583·Palm Springs, California and 10 others

CompletedSIR-Spheres® 90Y Microspheres Treatment of Uveal Melanoma Metastasized to LiverThe purpose of this study is to determine whether radiation provided locally to the liver tumor vasculature environment will demonstrate a response of tumor decline.NCT01473004·Philadelphia, Pennsylvania

TerminatedCMP-001 in Combination With Nivolumab Compared to Nivolumab Monotherapy in Subjects With Advanced MelanomaCMP-001-011 is a Phase 2/3 study of CMP-001 intratumoral (IT) and nivolumab intravenous (IV) compared to nivolumab monotherapy administered to participants with unresectable or…NCT04695977·Phoenix, Arizona and 19 others

TerminatedA Study of Adjuvant Pembrolizumab/Vibostolimab (MK-7684A) Versus Pembrolizumab for Resected High-Risk Melanoma in Participants With High-Risk Stage II-IV Melanoma (MK-7684A-010/KEYVIBE-010)The primary purpose of this study is to compare pembrolizumab/vibostolimab to pembrolizumab with respect to recurrence-free survival (RFS).NCT05665595·La Jolla, California and 204 others

CompletedRAD001 Plus Bevacizumab in Metastatic MelanomaThis is a non-randomized, open label Phase II study comparing bevacizumab and everolimus in the treatment of metastatic melanoma.NCT00591734·Fort Myers, Florida and 14 others

CompletedIntratumoral Injection of LTX-315 in Combination With Pembrolizumab in Advanced MelanomaATLAS-IT-05 was an open-label, single-arm study in patients with advanced melanoma accessible for injections (cutaneous, subcutaneous, lymph node, or intramuscular tumors) and who…NCT04796194·New York, New York and 9 others

TerminatedStudy of a Multi-Antigen Therapeutic Vaccine in Patients With Metastatic MelanomaPrimary objective: To evaluate the clinical activity of the vaccine regimen, as indicated by progression-free survival versus the clinical activity of the reference treatment.NCT00613509·Tucson, Arizona and 18 others

CompletedRadiation Therapy and MK-3475 for Patients With Recurrent/Metastatic Head and Neck Cancer, Renal Cell Cancer, Melanoma, and Lung CancerThis randomized clinical trial studies radiation therapy and MK-3475 in treating patients with head and neck cancer, kidney cancer, melanoma, or lung cancer that has returned, has…NCT02318771·Philadelphia, Pennsylvania

CompletedS0008: Chemotherapy Plus Biological Therapy in Treating Patients With MelanomaRATIONALE: Interferon alfa may interfere with the growth of cancer cells.NCT00006237·Birmingham, Alabama and 296 others

CompletedVaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic MelanomaRATIONALE: Vaccines may make the body build an immune response to kill tumor cells.NCT00006385·Scottsdale, Arizona and 31 others

CompletedTemozolomide and Everolimus in Treating Patients With Stage IV Melanoma That Cannot be Removed by SurgeryRATIONALE: Drugs used in chemotherapy, such as temozolomide, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from…NCT00521001·Aurora, Colorado and 197 others

TerminatedA Trial of Intratumoral Injections of SD-101 in Combination With Pembrolizumab in Patients With Metastatic Melanoma or Recurrent or Metastatic Head and Neck Squamous Cell CarcinomaThis is a phase 1b/2, open-label, multicenter trial designed to evaluate the safety, tolerability, biologic activity, and preliminary efficacy of intratumoral SD-101 injections in…NCT02521870·Birmingham, Alabama and 46 others

CompletedSafety of TKI258 in Advanced/Metastatic Melanoma SubjectsThis study is an open-label, dose-escalating study to delineate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of TKI258.NCT00303251·Louisville, Kentucky and 2 others

TerminatedNausea and Vomiting In Patients Receiving Consecutive Days of CisplatinThe purpose of this study is to observe the incidence of nausea with systemic chemotherapy that includes consecutive days (more than one day)of cisplatin medication.NCT00716560·Philadelphia, Pennsylvania

CompletedEvaluating Length of Treatment With PD-1/PD-L1 Inhibitor in Advanced Solid TumorsBased on the overwhelming positive response to this survey and the large number of patients being treated with PD-1/PD-L1 therapy in the UPMC system, the investigators are…NCT04157985·Pittsburgh, Pennsylvania

CompletedAnti-Tumor Activity Of SB-485232 In Patients With Previously Untreated Metastatic MelanomaThis Phase II study is designed to evaluate the anti-tumor activity of three dose groups of SB-485232 (0.01, 0.1, and 1.0 mg/kg/day) administered intravenously as a single agent…NCT00107718·Los Angeles, California and 19 others

CompletedA Phase 3 Pivotal Trial Comparing Allovectin-7® Alone vs Chemotherapy Alone in Patients With Stage 3 or Stage 4 MelanomaTo compare the safety and efficacy of Allovectin-7® versus Dacarbazine (DTIC)or Temozolomide (TMZ) in subjects with recurrent stage 3 or stage 4 melanoma.NCT00395070·Tucson, Arizona and 87 others

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