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Clareo Health | Melanoma Clinical Trials in Pennsylvania | 460 Studies

Clinical Trials MelanomaPennsylvania

Melanoma Clinical Trials in Pennsylvania

Find 460 clinical trials for melanoma near Pennsylvania. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 1-20 of 460 trials

CompletedA Study of XmAb®22841 Monotherapy & in Combination w/ Pembrolizumab in Subjects w/ Selected Advanced Solid TumorsThis is a Phase 1, multiple dose, ascending-dose escalation study and expansion study designed to define a maximum tolerated dose and/or recommended dose of XmAb22841 monotherapy…NCT03849469·Encinitas, California and 27 others

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Data from ClinicalTrials.govTerms

CompletedStudy to Explore the Safety, Tolerability and Efficacy of MK-3475 in Combination With INCB024360 in Participants With Selected CancersThe purpose of this study was to assess the safety, tolerability, and efficacy when combining MK-3475 and INCB024360 in participants with certain cancers.NCT02178722·La Jolla, California and 23 others

CompletedSWOG-9430: Surgery in Treating Patients With Metastatic MelanomaRATIONALE: Surgery may be effective therapy in treating patients with metastatic melanoma.NCT00002860·Anchorage, Alaska and 123 others

CompletedVaccine Therapy With or Without Cyclophosphamide in Treating Patients Who Have Undergone Surgery for Stage II, Stage III, or Stage IV MelanomaRATIONALE: Vaccines made from peptides may help the body build an effective immune response to kill tumor cells.NCT00118274·Philadelphia, Pennsylvania and 2 others

CompletedCollecting Tumor Samples From Patients With Gynecological TumorsThis laboratory study is collecting tumor tissue and blood samples from patients with gynecologic tumors.NCT00897442·Fayetteville, Arkansas and 186 others

CompletedTemsirolimus and Bevacizumab in Treating Patients With Stage III or Stage IV Malignant MelanomaThis phase II trial is studying how well giving temsirolimus together with bevacizumab works in treating patients with stage III or stage IV malignant melanoma.NCT00397982·Philadelphia, Pennsylvania and 1 other

TerminatedTrial of Intratumoral Injections of TTI-621 in Subjects With Relapsed and Refractory Solid Tumors and Mycosis FungoidesThis is a multicenter, open-label, phase 1 study conducted to test intratumoral injections of TTI-621 in subjects that have relapsed and refractory percutaneously accessible solid…NCT02890368·Duarte, California and 6 others

Active not recruitingA Study of Relatlimab Plus Nivolumab Versus Nivolumab Alone in Participants With Advanced MelanomaThe purpose of this study is to determine whether relatlimab in combination with nivolumab is more effective than nivolumab monotherapy in treating unresectable melanoma or…NCT03470922·Tucson, Arizona and 126 others

CompletedSafety of TKI258 in Advanced/Metastatic Melanoma SubjectsThis study is an open-label, dose-escalating study to delineate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of TKI258.NCT00303251·Louisville, Kentucky and 2 others

RecruitingMelanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous MelanomaPatients with a primary invasive melanoma are recommended to undergo excision of the primary lesion with a wide margin.NCT03860883·Mobile, Alabama and 191 others

CompletedCAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumorsNCT03504488·Tucson, Arizona and 58 others

TerminatedTovorafenib (DAY101) Monotherapy for Patients With Melanoma and Other Solid TumorsThis is a Phase 2, multi-center, open-label to evaluate the efficacy and safety of tovorafenib (DAY101) in participants ≥12 years of age with recurrent or progressive melanoma or…NCT04985604·Los Angeles, California and 19 others

RecruitingORACLE: Observation of ResiduAl Cancer With Liquid Biopsy EvaluationThe purpose of ORACLE is to demonstrate the ability of a novel ctDNA assay developed by Guardant Health to detect recurrence in individuals treated for early-stage solid tumors.NCT05059444·Birmingham, Alabama and 56 others

RecruitingA Trial of LNS8801 With or Without Pembrolizumab in Patients With Refractory MelanomaThe goal of this clinical trial is to understand if a new drug called LNS8801 can safely treat patients with melanoma.NCT06624644·Newport Beach, California and 8 others

CompletedA Study of Vemurafenib Adjuvant Therapy in Participants With Surgically Resected Cutaneous BRAF-Mutant MelanomaThis multicenter, randomized, double-blind, placebo-controlled study will evaluate the efficacy and safety of vemurafenib in participants with completely resected, cutaneous BRAF…NCT01667419·Birmingham, Alabama and 206 others

CompletedVaccine Therapy in Treating Patients With Recurrent Stage III or Stage IV Melanoma That Cannot Be Removed by SurgeryRATIONALE: Vaccines made from peptides may help the body build an effective immune response to kill tumor cells.NCT00471471·Pittsburgh, Pennsylvania

CompletedVaccine Therapy With or Without Biological Therapy in Treating Patients With Metastatic MelanomaRATIONALE: Vaccines may make the body build an immune response to kill tumor cells.NCT00006385·Scottsdale, Arizona and 31 others

TerminatedNY-ESO-1 Vaccine in Combination With Ipilimumab in Patients With Unresectable or Metastatic MelanomaThis was a Phase 1, open-label, non-randomized study of the combination of NY-ESO-1 plus ipilimumab in patients with unresectable or metastatic melanoma for whom treatment with…NCT01810016·New York, New York and 4 others

Active not recruitingMAGE-A4ᶜ¹º³²T for Multi-TumorThis study will investigate the safety and tolerability of MAGE-A4ᶜ¹º³²T cell therapy in subjects who have the appropriate HLA-A2 tissue marker and whose urinary bladder…NCT03132922·Miami, Florida and 10 others

CompletedA Study of the Safety and Tolerance of CAN04 and Pembrolizumab in Combination With and Without Carboplatin and Pemetrexed in Subjects With Solid TumorsThis study will consider the safety and effectiveness of a study drug, CAN04, in combination with pembrolizumab, in the treatment of incurable or metastatic non-small-cell lung…NCT04452214·Aurora, Colorado and 2 others

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Other Conditions in Pennsylvania

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma