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Clareo Health | Melanoma Clinical Trials in Ohio | 326 Studies

Clinical Trials MelanomaOhio

Melanoma Clinical Trials in Ohio

Find 326 clinical trials for melanoma near Ohio. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Ohio

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 121-140 of 326 trials

Active not recruitingA Study to Evaluate ARV-806 in Adults With Advanced Cancer That Has the KRAS G12D MutationThis is a study to evaluate the safety and potential anti-tumor activity of an investigational agent called ARV-806 in Adults with Advanced Cancer having a specific Kirsten rat…NCT07023731·Phoenix, Arizona and 13 others TerminatedA Phase III Study to Test the Benefit of a New Kind of Anti-cancer Treatment in Patients With Melanoma, After Surgical Removal of Their TumorThe purpose of this clinical trial is to evaluate the benefit of the immunotherapeutic product GSK 2132231A in preventing disease relapse when given to melanoma patients, after…NCT00796445·Birmingham, Alabama and 256 others

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Data from ClinicalTrials.govTerms

CompletedA Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced MalignanciesThis is a study to determine the maximum tolerated dose (MTD) for CDX-1140 (CD40 antibody), either alone or in combination with CDX-301 (FLT3L), pembrolizumab, or chemotherapy and…NCT03329950·Scottsdale, Arizona and 10 others

CompletedInterferon Alfa and Thalidomide in Treating Patients With Stage IV MelanomaRATIONALE: Interferon alfa may interfere with the growth of cancer cells and slow the growth of the tumor.NCT00026520·Mobile, Alabama and 93 others

TerminatedStudy of Motexafin Gadolinium With Whole Brain Radiation Therapy Followed by Stereotactic Radiosurgery Boost in the Treatment of Patients With Brain MetastasesThe primary purpose of the study is to evaluate if motexafin gadolinium with whole brain radiation therapy followed by a stereotactic radiosurgery boost is a safe and effective…NCT00121420·Phoenix, Arizona and 11 others

CompletedStudy to Evaluate Treatment of Dabrafenib Plus Trametinib in Subjects With BRAF Mutation-Positive Melanoma That Has Metastasized to the BrainThis is a multi-cohort, open label, Phase II study with Dabrafenib (GSK2118436) and Trametinib (GSK1120212) combination therapy in subject with BRAF mutation-positive melanoma…NCT02039947·Birmingham, Alabama and 46 others

CompletedStudy of the CD40 Agonistic Monoclonal Antibody APX005MThis study is a phase 1 open-label dose escalation study of the immuno-activating monoclonal antibody APX005M in adults with solid tumors.NCT02482168·Duarte, California and 2 others

CompletedAn Open-Label, 2-Cohort, Multicenter, Study of Lenvatinib in Previously Treated Subjects With Unresectable Stage III or Stage IV MelanomaThe purpose of this study is to assess the objective response rate of lenvatinib in previously treated participants with American Joint Committee on Cancer (AJCC) unresectable…NCT01136967·Birmingham, Alabama and 94 others

TerminatedStage IV Surgery Versus Best Medical TherapyThis study will establish the role of surgical versus nonsurgical approaches in patients whose melanoma has spread to distant sites.NCT01013623·Sacramento, California and 18 others

CompletedStudy of Everolimus With Paclitaxel and Carboplatin in Patients With Metastatic MelanomaBased on data demonstrating synergy between paclitaxel and mammalian target of rapamycin (mTOR) inhibition, the investigators propose that the addition of everolimus to paclitaxel…NCT01014351·Fort Myers, Florida and 11 others

Active not recruitingNBTXR3 Activated by Radiotherapy for Patients With Advanced Cancers Treated With An Anti-PD-1 TherapyThe 1100 study is an open-label, Phase I, dose escalation and expansion prospective clinical study to assess the safety of intratumoral injection of NBTXR3 activated by…NCT03589339·San Francisco, California and 12 others

RecruitingA Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid TumorsThis is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent and in combination with…NCT05592626·Sacramento, California and 18 others

TerminatedGamma-Secretase/Notch Signalling Pathway Inhibitor RO4929097 in Treating Patients With Stage IV MelanomaThis phase II trial is studying how well gamma-secretase/Notch signalling pathway inhibitor RO4929097 works in treating patients with stage IV melanoma.NCT01120275·Mobile, Alabama and 177 others

CompletedCarboplatin and Paclitaxel With or Without Sorafenib Tosylate in Treating Patients With Stage III or Stage IV Melanoma That Cannot Be Removed by SurgeryThis randomized phase III trial studies carboplatin, paclitaxel, and sorafenib tosylate to see how well they work compared to carboplatin and paclitaxel in treating patients with…NCT00110019·Birmingham, Alabama and 218 others

CompletedA Study Comparing Trametinib and Dabrafenib Combination Therapy to Dabrafenib Monotherapy in Subjects With BRAF-mutant MelanomaThis was a two-arm, double-blinded, randomized, Phase III study comparing dabrafenib and trametinib combination therapy to dabrafenib administered with a placebo (dabrafenib…NCT01584648·Scottsdale, Arizona and 120 others

CompletedA Pharmacokinetics (PK) Study to Investigate the Effect of Rifampin on PK of Vemurafenib (Zelboraf)This open-label, multi-center, three-period, one-sequence study will investigate the effect of rifampin on the PK of vemurafenib in participants with unresectable…NCT01765543·Rogers, Arkansas and 14 others

CompletedMulticenter Selective Lymphadenectomy Trial II (MSLT-II)Subjects must be diagnosed with melanoma. All subjects receive sentinel lymphadenectomy.NCT00297895·San Diego, California and 62 others

CompletedReal-world Outcomes Among Patients With Melanoma Treated With Neoadjuvant Nivolumab+Relatlimab or Nivolumab+IpilimumabThe purpose of this study is to understand the characteristics of adults diagnosed with with clinically palpable stage III resectable melanoma, the associated treatment patterns…NCT07091695·Dublin, Ohio

CompletedGSK1120212 vs Chemotherapy in Advanced or Metastatic BRAF V600E/K Mutation-positive MelanomaThis is a two-arm, open-label, randomized Phase III study comparing single agent GSK1120212 to chemotherapy (either dacarbazine or paclitaxel) in subjects with Stage IIIc or Stage…NCT01245062·Tucson, Arizona and 111 others

TerminatedStudy Of Zelboraf (Vemurafenib) in Patients With Locally-Advanced, Unresectable, Stage IIIc Or Metastatic Melanoma and Activating Exon 15 BRAF Mutations Other Than V600EThis is an open-label, multicenter, single-agent, phase II study of continuous oral Zelboraf (vemurafenib) in participants with locally-advanced, unresectable, stage IIIc or…NCT01586195·Tucson, Arizona and 14 others

Other Conditions in Ohio

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma