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Clinical Trials MelanomaNashville

Melanoma Clinical Trials in Nashville

Find 288 clinical trials for melanoma near Nashville, Tennessee. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Nashville

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 141-160 of 288 trials

Active not recruitingStudy of LY3410738 Administered to Patients With Advanced Solid Tumors With IDH1 or IDH2 MutationsThis is an open-label, multicenter Phase 1 study to evaluate safety, tolerability and preliminary efficacy of oral LY3410738 in patients with isocitrate dehydrogenase 1 (IDH1)…NCT04521686·Phoenix, Arizona and 32 others

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Data from ClinicalTrials.govTerms

Clareo Health | Melanoma Clinical Trials in Nashville | 288 Studies

CompletedSargramostim, Vaccine Therapy, or Sargramostim and Vaccine Therapy in Preventing Disease Recurrence in Patients With Melanoma That Has Been Removed By SurgeryThis randomized phase III trial studies sargramostim or vaccine therapy alone to see how well they work compared to sargramostim and vaccine therapy together in preventing disease…NCT01989572·Birmingham, Alabama and 147 others

TerminatedPembrolizumab With Talimogene Laherparepvec or Placebo in Unresected MelanomaThe primary objectives of the Phase 1b part of the study are to evaluate the safety, as assessed by incidence of dose limiting toxicity (DLT), of talimogene laherparepvec in…NCT02263508·Birmingham, Alabama and 160 others

CompletedStudy of Nivolumab Given Sequentially With Ipilimumab in Subjects With Advanced or Metastatic Melanoma (CheckMate 064)The purpose of this study is to evaluate the safety and efficacy of a sequential combination therapy of Nivolumab and IpilimumabNCT01783938·Tampa, Florida and 10 others

RecruitingStudy of AU-007, A Monoclonal Antibody That Binds to IL-2 and Inhibits IL-2Rα Binding, in Patients With Unresectable Locally Advanced or Metastatic CancerThis is a first in human, open-label, multi-center Phase 1 / 2 study to evaluate the safety, tolerability, and initial efficacy of AU-007, also known as imneskibart, in patients…NCT05267626·Miami, Florida and 16 others

CompletedStudy of CP-675,206 in Refractory MelanomaCP-675,206 is a fully human monoclonal antibody (mAb). It binds to the CTLA4 molecule, which is expressed on the surface of activated T lymphocytes.NCT00254579·Scottsdale, Arizona and 64 others

CompletedStudy of Cabozantinib (XL184) in Adults With Advanced MalignanciesThis is a Phase 2 study to evaluate the efficacy and safety of cabozantinib (XL184) in subjects with selected advanced tumor types.NCT00940225·Scottsdale, Arizona and 46 others

CompletedSafety, Tolerability and Efficacy Study of the Monoclonal Antibody, CT-011, in Patients With Metastatic MelanomaThe purpose of this research study is to see if the study drug, CT-011, is safe to give and if it helps people with melanoma that has spread to other areas of their body.NCT01435369·New Haven, Connecticut and 17 others

CompletedStudy to Assess the Tolerability of a Bispecific Targeted Biologic IMCgp100 in Malignant MelanomaIMCgp100 is a new biological therapy designed for the treatment of melanoma skin cancer. The drug is designed to target melanoma cells and stimulate immune cells to kill them.NCT01211262·Los Angeles, California and 8 others

RecruitingStudy of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)This is a Phase 1/2, open-label, non-randomized, 4-part trial to determine the safety profile and identify the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D)…NCT04198766·Duarte, California and 59 others

UnknownVaccine Therapy for Patients With Stage IV MelanomaThis is a Phase III study in patients with melanoma that has spread to the lymph nodes and/or a distant organ, and who have had all of their cancer surgically removed.NCT00052156·Tucson, Arizona and 76 others

CompletedHigh-Dose Interferon Alfa in Treating Patients With Stage II or Stage III MelanomaRATIONALE: Interferon alfa may interfere with the growth of cancer cells.NCT00003641·Birmingham, Alabama and 532 others

CompletedPhase 1, First-in-human, Dose-finding and Expansion Study to Evaluate XmAb®808 in Combination With Pembrolizumab in Advanced Solid TumorsThe purpose of this study is to evaluate the safety, tolerability, and pharmacokinetics of intravenous (IV) administration of XmAb808 in combination with pembrolizumab in subjects…NCT05585034·Los Angeles, California and 11 others

CompletedA Study of GSK2118436 in BRAF Mutant Metastatic MelanomaBRF113710 is a Phase II, single-arm, open-label study to assess the efficacy, safety, and tolerability of GSK2118436 administered twice daily as a single agent in subjects with…NCT01153763·Los Angeles, California and 22 others

Active not recruitingTargeted Therapy Directed by Genetic Testing in Treating Patients With Advanced Refractory Solid Tumors, Lymphomas, or Multiple Myeloma (The MATCH Screening Trial)This phase II MATCH screening and multi-sub-trial studies how well treatment that is directed by genetic testing works in patients with solid tumors, lymphomas, or multiple…NCT02465060·Birmingham, Alabama and 1409 others

TerminatedFT538 in Combination With Monoclonal Antibodies in Advanced Solid TumorsThis is a Phase 1 dose-finding study of FT538 in combination with monoclonal antibodies.NCT05069935·Hackensack, New Jersey and 3 others

Active not recruitingAn Efficacy Study of Adjuvant Treatment With the Personalized Cancer Vaccine mRNA-4157 and Pembrolizumab in Participants With High-Risk Melanoma (KEYNOTE-942)The purpose of this study is to assess whether postoperative adjuvant therapy with mRNA-4157 and pembrolizumab improves recurrence free survival (RFS) compared to pembrolizumab…NCT03897881·Tucson, Arizona and 22 others

CompletedBioequivalence & Food Effect Study in Patients With Solid Tumor or Hematologic MalignanciesThis is a Phase 1, open-label, multicenter, randomized, 2-stage crossover study consisting of 2 phases: Stage I - Pharmacokinetics (Bioequivalence), with an Extension Stage II -…NCT02223052·Scottsdale, Arizona and 9 others

CompletedOpen-label Study to Investigate the Safety, PK, and Pharmacodynamics of GSK1120212 in Subjects With Solid Tumors or LymphomaMEK111054 is a first-time-in-human, open-label study to determine recommended dose and regimen for the orally administered GSK1120212. The study consists of three parts.NCT00687622·Scottsdale, Arizona and 11 others

CompletedA Phase 1 Study of Nivolumab (BMS-936558) in Subjects With Advanced or Recurrent MalignanciesThe purpose of this study is to determine the safety and effectiveness of MDX-1106 in patients with certain types of cancer.NCT00730639·Scottsdale, Arizona and 12 others

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