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Clareo Health | Melanoma Clinical Trials in Nashville | 285 Studies

Clinical Trials MelanomaNashville

Melanoma Clinical Trials in Nashville

Find 285 clinical trials for melanoma near Nashville, Tennessee. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Nashville

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 41-60 of 285 trials

CompletedSU011248 in Patients With Metastatic Mucosal or Acral/Lentiginous MelanomaThe purpose of this study is to evaluate how effective Sunitinib works in treating acral lentiginous and mucosal melanoma which has spread beyond the local region.NCT00577382·Boston, Massachusetts and 4 others Active not recruitingADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors (SURPASS)This study will investigate the safety and tolerability of ADP-A2M4CD8 T-cell therapy in subjects who have the appropriate human leukocyte antigen (HLA) and MAGE-A4 tumor antigen.NCT04044859·Orlando, Florida and 16 others

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Data from ClinicalTrials.govTerms

TerminatedA Phase Ib Study of LXH254-centric Combinations in NSCLC or MelanomaTo characterize safety and tolerability and identify a recommended dose and regimen for the LXH254 in combination with LTT462 or trametinib or ribociclib.NCT02974725·San Diego, California and 31 others

CompletedSRK-181 Alone or in Combination With Anti-PD-(L)1 Antibody Therapy in Patients With Locally Advanced or Metastatic Solid Tumors (DRAGON)This was a multi-center, open-label, Phase 1, first-in-human (FIH), dose-escalation, and dose expansion study to evaluate the safety, tolerability, pharmacokinetics (PK)…NCT04291079·Fullerton, California and 21 others

CompletedPH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced MelanomaThe purpose of this study is to evaluate pharmacodynamic changes of Nivolumab and Nivolumab in combination with Ipilimumab treatment on the biomarkers measured in the peripheral…NCT01621490·Los Angeles, California and 13 others

RecruitingPilot Study of Bone Mineral Density Changes During Anti-PD-1 ImmunotherapyImmune checkpoint inhibitors (ICIs) have revolutionized cancer treatment and work by blocking protein interactions that normally prevent the immune system from recognizing and…NCT07555210·Nashville, Tennessee

TerminatedFT538 in Combination With Monoclonal Antibodies in Advanced Solid TumorsThis is a Phase 1 dose-finding study of FT538 in combination with monoclonal antibodies.NCT05069935·Hackensack, New Jersey and 3 others

Enrolling by invitationA Study to Learn About the Long-Term Health of Adult Participants From a Previous Study of a New Melanoma TreatmentThis study is researching the long-term effects of a combination of experimental drugs called fianlimab and cemiplimab.NCT06848088·Los Angeles, California and 10 others

TerminatedA Personal Cancer Vaccine (NEO-PV-01) and APX005M or Ipilimumab With Nivolumab in Patients With Advanced MelanomaThe primary purpose of this study is to demonstrate that the NEO-PV-01 vaccine, either with APX005M or ipilimumab, and nivolumab is safe for the treatment of patients with…NCT03597282·Scottsdale, Arizona and 7 others

TerminatedA Study of PF-07820435 as a Single Agent and in Combination in Participants With Advanced Solid TumorsThis study aims to evaluate the safety, and early signals of anti-tumor activity of PF-07820435 when administered alone (Part 1A) or in combination with sasanlimab (Part 1B; Part…NCT06285097·Sarasota, Florida and 9 others

TerminatedThis SCR-103 Protocol Will Permit Sites to Proactively Assess TAA, HLA and HPV-16 Status in Patients With Selected Solid Tumors to Determine Suitability for Repertoire Immune Medicines Treatment Protocols.The purpose of this study is to obtain archived tumor tissue or pre-existing antigen expression data from patients with Head and Neck, Cervical, Melanoma and Non-Small Cell Lung…NCT05061940·Scottsdale, Arizona and 2 others

RecruitingR-5780-01 In Combination With PD-1 Checkpoint Inhibitors (Checkpoint Protein on Immune Cells Called T Cells) in Patients With Solid TumorsThe goal of this study is determine the safety and tolerability of orally taken probiotic (R-5780) in patients currently on a PD-1 Pathway Checkpoint Inhibitor (checkpoint protein…NCT06398418·Denver, Colorado and 1 other

Active not recruitingA Clinical Trial of Three Study Medicines (Encorafenib, Binimetinib, and Pembrolizumab) in Patients With Advanced or Metastatic MelanomaThe purpose of this study is to learn about the effects of three study medicines (encorafenib, binimetinib, and pembrolizumab) given together for the treatment of melanoma…NCT04657991·Orlando, Florida and 150 others

Active not recruitingDabrafenib and Trametinib Followed by Ipilimumab and Nivolumab or Ipilimumab and Nivolumab Followed by Dabrafenib and Trametinib in Treating Patients With Stage III-IV BRAFV600 MelanomaThis phase III trial studies how well initial treatment with ipilimumab and nivolumab followed by dabrafenib and trametinib works and compares it to initial treatment with…NCT02224781·Birmingham, Alabama and 837 others

RecruitingDESTINY-PANTUMOUR04This study will evaluate the effectiveness of T-DXd in patients with HER2-positive (IHC 3+) locally advanced, unresectable, or metastatic solid tumors who have received prior…NCT07124000·Birmingham, Alabama and 17 others

CompletedA Safety and Efficacy Study of Intetumumab, Alone and in Combination With Dacarbazine, in Participants With Stage 4 MelanomaThe purpose of this study is to evaluate the safety and effectiveness of the intetumumab, alone and in combination with dacarbazine, in patients with stage 4 melanoma.NCT00246012·Scottsdale, Arizona and 31 others

TerminatedA Study to Learn About PF-07921585 Alone or With Other Anti-cancer Medicines in People With CancerThe purpose of this study is to learn about the safety and effects of the study medicine (called PF-07921585) in people with cancer that has advanced or spread to other parts of…NCT06580938·Fayetteville, Arkansas and 8 others

CompletedA Phase 1 Study of Pegilodecakin (LY3500518) in Participants With Advanced Solid TumorsThis is a first-in-human, open-label, dose escalation study to evaluate the safety and tolerability of pegilodecakin in participants with advanced solid tumors, dosed daily…NCT02009449·Los Angeles, California and 9 others

TerminatedA Phase 1b Trial of ATRC-101 in Adults With Advanced Solid MalignanciesATRC-101-A01 is a Phase 1b, open-label dose escalation and expansion trial of ATRC-101, an engineered fully human immunoglobulin G, subclass 1 (IgG1) antibody derived from a…NCT04244552·Phoenix, Arizona and 18 others

Active not recruitingIDE196 (Darovasertib) in Combination With Crizotinib as First-line Therapy in Metastatic Uveal MelanomaThis is a Phase 2/3, multi-arm, multi-stage, open-label study of human leukocyte antigen (HLA)-A\*02:01 negative participants with metastatic uveal melanoma (MUM) who will be…NCT05987332·Scottsdale, Arizona and 67 others

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