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Clareo Health | Melanoma Clinical Trials in Maryland | 303 Studies

Clinical Trials MelanomaMaryland

Melanoma Clinical Trials in Maryland

Find 303 clinical trials for melanoma near Maryland. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Maryland

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 261-280 of 303 trials

TerminatedTumor Cell Vaccine for Patients Undergoing Surgery for Sarcomas, Melanomas, Germ Cell Tumors, or Malignancies That Have Metastasized to the Lungs, Pleura, or MediastinumBackground: \- Certain types of cancers, including sarcoma and melanoma, have specific antigens (protein molecules) on their surfaces.NCT01313429·Bethesda, Maryland CompletedRadiation, Chemotherapy, Vaccine and Anti-MART-1 and Anti-gp100 Cells for Patients With Metastatic MelanomaBackground: * Melanoma antigen recognized by T-cells (MART-1) and gp100 are two genes found in melanoma cells.NCT00923195·Bethesda, Maryland

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Data from ClinicalTrials.govTerms

CompletedSubstudy 02A: Safety and Efficacy of Pembrolizumab in Combination With Investigational Agents in Participants With Programmed Cell-death 1 (PD-1) Refractory Melanoma (MK-3475-02A/KEYMAKER-U02)Substudy 02A is part of a larger research study that is testing experimental treatments for melanoma, a type of skin cancer. The larger study is the umbrella study.NCT04305041·Los Angeles, California and 35 others

Enrolling by invitationFollow Up Protocol for Subjects Previously Enrolled on NCI Surgery Branch StudiesBackground: The NCI Surgery Branch has developed experimental therapies that involve taking white blood cells from participants' tumor or from their blood, growing them in the…NCT00923026·Bethesda, Maryland

CompletedSafety Study of MGA271 in Refractory CancerThe purpose of this study is to evaluate the safety of MGA271 when given by intravenous (IV) infusion to patients with refractory cancer.NCT01391143·Los Angeles, California and 11 others

CompletedCollecting Solid Tumor Tissue to Identify New TreatmentsBackground: The NCI Surgery Branch has developed experimental therapies that involve taking white blood cells from patients' tumor or from their blood, growing them in the…NCT01658917·Bethesda, Maryland

CompletedHepatic Arterial Infusion of Melphalan With Hepatic Perfusion in Treating Patients With Unresectable Liver CancerRATIONALE: Hepatic arterial infusion uses a catheter to deliver anticancer substances directly into the liver.NCT00096083·Bethesda, Maryland

CompletedPH 1 Biomarker Study of Nivolumab and Ipilimumab and Nivolumab in Combination With Ipilimumab in Advanced MelanomaThe purpose of this study is to evaluate pharmacodynamic changes of Nivolumab and Nivolumab in combination with Ipilimumab treatment on the biomarkers measured in the peripheral…NCT01621490·Los Angeles, California and 13 others

CompletedVaccine Therapy With or Without Interleukin-2 in Treating Patients With Recurrent Metastatic MelanomaRATIONALE: Vaccines made from an antigen combined with a modified virus may make the body build an immune response to kill tumor cells.NCT00019175·Bethesda, Maryland

CompletedHepatic Arterial Infusion With Melphalan Compared With Standard Therapy in Treating Patients With Unresectable Liver Metastases Due to MelanomaRATIONALE: Drugs used in chemotherapy, such as melphalan, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping them from dividing.NCT00324727·Santa Monica, California and 11 others

CompletedVaccine Treatment in Combination With IL-2 and Treated Lymphocytes for Advanced MelanomaThis study will examine the effectiveness of treating advanced melanoma with special tumor-fighting cells taken from the patient's blood or tumor and grown in the laboratory.NCT00080353·Bethesda, Maryland

UnknownStudy of NGM707 As Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor MalignanciesStudy of NGM707 as Monotherapy and in Combination with Pembrolizumab in Advanced or Metastatic Solid Tumor MalignanciesNCT04913337·Los Angeles, California and 26 others

TerminatedTrial of Vemurafenib/Cobimetinib With or Without Bevacizumab in Patients With Stage IV BRAFV600 Mutant MelanomaThis phase 2 clinical trial randomizes patients with BRAF mutant melanoma to either (1) standard of care (SOC) - BRAF inhibitor vemurafenib in combination with MEK inhibitor…NCT01495988·Los Angeles, California and 13 others

TerminatedModified White Blood Cells That Secrete IL-2 and Express a Protein That Targets the ESO-1tumor Protein for Metastatic CancerBackground: \- A new cancer treatment involves collecting white blood cells from an individual, modifying them to secrete IL-2 and target the ESO-1 protein expressed on some…NCT01457131·Bethesda, Maryland

CompletedStudy of Ipilimumab (MDX-010) Monotherapy in Patients With Previously Treated Unresectable Stage III or IV MelanomaThe purpose of this clinical research study is to compare the best overall response rate (BORR)(as per modified WHO criteria) in patients with previously treated…NCT00289640·Tucson, Arizona and 61 others

Enrolling by invitationNatural History Study of Early Life Exposures in Agriculture (ELEA)Study Description: ELEA is an observational cohort study that will collect exposure information and biospecimens from the adult children of the Agricultural Health Study (AHS)…NCT07328516·Bethesda, Maryland

CompletedLymphocyte Re-infusion During Immune Suppression to Treat Metastatic MelanomaThis experiment will test the safety and effectiveness of a treatment for melanoma in which certain lymphocytes (a type of white blood cell) are taken from the patient, grown in…NCT00001832·Bethesda, Maryland

RecruitingA Study of Therapeutic Drug Monitoring-Based Atezolizumab DosingBackground: A type of drug called monoclonal antibody immune checkpoint inhibitors are often used in cancer treatment.NCT06066138·Bethesda, Maryland

CompletedCyclophosphamide and Fludarabine Followed By Interleukin-2 Gene-Modified Tumor Infiltrating Lymphocytes in Treating Patients With Metastatic MelanomaRATIONALE: Drugs used in chemotherapy such as cyclophosphamide and fludarabine use different ways to stop tumor cells from dividing so they stop growing or die.NCT00062036·Bethesda, Maryland and 1 other

TerminatedStudy of Autologous Tumor Infiltrating Lymphocytes in Patients With Solid TumorsA prospective, open-label, multi-cohort, non-randomized, multicenter Phase 2 study evaluating adoptive cell therapy (ACT) with TIL \[LN-144/LN-145 (lifileucel)\] in combination…NCT03645928·La Jolla, California and 33 others

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Other Conditions in Maryland

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma