Follow Up Protocol for Subjects Previously Enrolled on NCI Surgery Branch Studies

Background: * Patients receiving care at the NIH Clinical Center are required to be enrolled on a clinical protocol. * Following participation in a treatment protocol, it may be in the best interest of the patient to continue to be followed at the Clinical Center. * The National Cancer Institute Surgery Branch (NCI-SB) conducts clinical trials utilizing gene transfer. The current U.S. Food and Drug Administration (FDA) requirements for long-term follow-up are up to fifteen years for some products. As this time-period is frequently longer than studies are expected to be open, a long-term follow-up protocol is necessary to ensure the follow-up of these participants. Objective: -Primary objective: --Provide a mechanism for long-term follow-up of participants who have participated in research studies in the NCI-SB. Eligibility: * Age greater than or equal to 18 years. * Participant has been enrolled on an NCI-SB treatment protocol. Design: * Participant will undergo physical exams, laboratory evaluation, imaging, or phone follow-up as clinically indicated. * Procedures that entail more than minimal risk to the patient should not be performed for research purposes on this protocol.