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Clinical Trials MelanomaMaryland

Melanoma Clinical Trials in Maryland

Find 303 clinical trials for melanoma near Maryland. Connect with research centers in your area.

All Melanoma trials nationwide All trials in Maryland

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 181-200 of 303 trials

CompletedSafety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory CancerThe purpose of this study is to evaluate the safety of enoblituzumab (MGA271) in combination with Keytruda (pembrolizumab) when given to patients with B7-H3-expressing melanoma…NCT02475213·Scottsdale, Arizona and 19 others CompletedMechanism of Action of High-Dose IL-2 (Aldesleukin) in Metastatic Melanoma and Kidney CancerBackground: -Although IL-2 can shrink tumors in about 20 percent of patients with metastatic kidney cancer and in 15 percent of patients with metastatic melanoma, it is not fully…NCT00304460·Bethesda, Maryland

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Data from ClinicalTrials.govTerms

Active not recruitingBasket Study of Entrectinib (RXDX-101) for the Treatment of Patients With Solid Tumors Harboring NTRK 1/2/3 (Trk A/B/C), ROS1, or ALK Gene Rearrangements (Fusions)This is an open-label, multicenter, global Phase 2 basket study of entrectinib (RXDX-101) for the treatment of patients with solid tumors that harbor an NTRK1/2/3, ROS1, or ALK…NCT02568267·Phoenix, Arizona and 119 others

Active not recruitingIpilimumab or High-Dose Interferon Alfa-2b in Treating Patients With High-Risk Stage III-IV Melanoma That Has Been Removed by SurgeryThis randomized phase III trial studies ipilimumab to see how well it works compared to high-dose interferon alfa-2b in treating patients with high-risk stage III-IV melanoma that…NCT01274338·Birmingham, Alabama and 936 others

TerminatedPhase II Study of Aldesleukin (IL-2) Following the Administration of Zanolimumab (Anti-CD4mAb) in Metastatic Melanoma and Metastatic Renal CancerBackground: * Aldesleukin (IL-2) is a drug that can help to shrink tumors in some patients with metastatic renal cancer and metastatic melanoma.NCT01160445·Bethesda, Maryland

CompletedDacarbazine and/or Cisplatin Compared With Complete Metastasectomy in Treating Patients With Stage IV MelanomaRATIONALE: Drugs used in chemotherapy, such as dacarbazine and cisplatin, work in different ways to stop tumor cells from dividing so they stop growing or die.NCT00072124·Bethesda, Maryland

RecruitingAdministering Peripheral Blood Lymphocytes Transduced With a CD70-Binding Chimeric Antigen Receptor to People With CD70 Expressing CancersBackground: In a new cancer therapy, researchers take a person s blood, select a certain white blood cell to grow in the lab, and then change the genes of these cells using a…NCT02830724·Bethesda, Maryland

CompletedA Study of MGC018 in Combination With MGD019 in Participants With Advanced Solid TumorsStudy CP-MGC018-02 is a study of vobramitamab duocarmazine (MGC018) in combination with lorigerlimab (MGD019).NCT05293496·Los Angeles, California and 9 others

CompletedImmunization of HLA-A201 Patients With Metastatic Melanoma Using a Combination of Immunodominant Peptides From Three Melanoma Antigens, MART-1, GP100 and TyrosinaseThis is a study of a melanoma tumor antigen peptide vaccine.NCT00001685·Bethesda, Maryland

WithdrawnNeoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Nivolumab or Neoadjuvant Nivolumab+Ipilimumab Followed by Adjuvant Observation Compared With Adjuvant Nivolumab in Treatment-Naive High-risk Melanoma ParticipantsThe purpose of this study is to evaluate the role of neoadjuvant immunotherapy and to demonstrate high pathologic complete response (pCR) and near pCR rates in melanoma…NCT04495010·Gilbert, Arizona and 117 others

CompletedPhase II Trial of Allovectin-7® for Metastatic MelanomaThe purpose of this clinical trial is to determine if Allovectin-7®, an experimental gene-based immunotherapy, can shrink melanoma tumors.NCT00044356·Tucson, Arizona and 15 others

TerminatedImmunotherapy Using 41BB Selected Tumor Infiltrating Lymphocytes for Patients With Metastatic MelanomaBackground: The National Cancer Institute (NCI) Surgery Branch has developed an experimental therapy that involves taking white blood cells from patients' tumors, growing them in…NCT02111863·Bethesda, Maryland

UnknownVaccine Therapy for Patients With Stage III MelanomaThis is a Phase 3 study in patients with melanoma that has spread to the lymph nodes (stage III), and who have had all of their cancer surgically removed.NCT00052130·Tucson, Arizona and 79 others

CompletedDabrafenib With Trametinib in the Adjuvant Treatment of High-risk BRAF V600 Mutation-positive Melanoma (COMBI-AD).This was a two-arm, randomized, double-blind Phase III study of dabrafenib in combination with trametinib versus 2 placebos in the adjuvant treatment of melanoma after surgical…NCT01682083·Birmingham, Alabama and 167 others

CompletedA Phase I Study of Intravenous Recombinant Human IL-15 in Adults With Refractory Metastatic Malignant Melanoma and Metastatic Renal Cell CancerBackground: * Recombinant human interleukin-15 (rhIL-15) is a substance that is naturally produced in the body that has many properties that increase the activity and strength of…NCT01021059·Bethesda, Maryland

TerminatedTumor Cell Vaccines and ISCOMATRIX With Chemotherapy After Tumor RemovalBackground: \- A tumor cell vaccine is an experimental cancer treatment. Cancer cells are collected from a patient and then used to develop a vaccine.NCT01341496·Bethesda, Maryland

CompletedVaccine Therapy With or Without Interleukin-2 in Treating Patients With Metastatic MelanomaRATIONALE: Vaccines may make the body build an immune response to kill tumor cells.NCT00019669·Bethesda, Maryland

CompletedVaccine Therapy in Treating Patients With Refractory Metastatic MelanomaRATIONALE: Vaccines may make the body build an immune response to kill tumor cells.NCT00020397·Bethesda, Maryland

CompletedA Study of AMNN107 in the Treatment of Metastatic and/or Inoperable Melanoma Harboring a c-Kit MutationThe purpose of this study is to determine whether nilotinib is efficacious in the treatment of metastatic and/or inoperable melanoma harboring a c-Kit mutation.NCT01028222·Duarte, California and 48 others

CompletedLenalidomide (Revlimid) to Treat Advanced Ocular MelanomaThis study will test whether an experimental drug called Revlimid (lenalidomide) can reduce tumor size and prolong survival in patients with metastatic melanoma (melanoma that has…NCT00109005·Bethesda, Maryland

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Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Leukemia Lymphoma