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Clareo Health | Lung Cancer Clinical Trials in Pittsburgh | 380 Studies

Clinical Trials Lung CancerPittsburgh

Lung Cancer Clinical Trials in Pittsburgh

Find 380 clinical trials for lung cancer near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Pittsburgh

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

Who can join

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Showing 361-380 of 380 trials

TerminatedASA404 or Placebo in Combination With Paclitaxel and Carboplatin as First-Line Treatment for Stage IIIb/IV Non-Small Cell Lung CancerThe purpose of this study is to determine if adding ASA404 to standard chemotherapy makes the cancer treatment more effective in patients with advanced lung cancer.NCT00662597·Mobile, Alabama and 247 others

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Data from ClinicalTrials.govTerms

RecruitingKO-2806 Monotherapy and Combination Therapies in Advanced Solid TumorsThis first-in-human (FIH) dose-escalation and dose-validation/expansion study will assess KO-2806, a farnesyltransferase inhibitor (FTI), as a monotherapy and in combination, in…NCT06026410·Phoenix, Arizona and 37 others

CompletedPhase II Anti-PD1 Epigenetic Therapy Study in NSCLC.Response RateNCT01928576·Los Angeles, California and 4 others

TerminatedTovorafenib (DAY101) or in Combination With Pimasertib for Participants With Melanoma and Other Solid TumorsThis is a subprotocol of Master Protocol DAY101-102 and is a Phase 1b/2, multi-center, open label subprotocol of participants ≥12 years of age, with recurrent or progressive solid…NCT07121829·Los Angeles, California and 9 others

Active not recruitingA Study of the Pan-KRAS Inhibitor LY4066434 in Participants With KRAS Mutant Solid TumorsThe main purpose of the study is to assess whether the study drug, LY4066434, is safe and tolerable when administered to participants with locally advanced or metastatic solid…NCT06607185·Birmingham, Alabama and 44 others

TerminatedA Study of Sotorasib (AMG 510) in Participants With Stage IV NSCLC Whose Tumors Harbor a KRAS p.G12C Mutation in Need of First-line TreatmentThe main objective of this study is to evaluate the tumor objective response rate (ORR) assessed by Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 criteria in…NCT04933695·Birmingham, Alabama and 66 others

CompletedVopratelimab and a CTLA-4 Inhibitor in PD-1/PD-L1 Inhibitor Experienced Subjects With NSCLC or Urothelial CancerJTX-2011-201 is a Phase 2, open label clinical study of vopratelimab (JTX-2011) and ipilimumab in adult subjects with non-small cell lung cancer (NSCLC) or urothelial cancer to…NCT03989362·Beverly Hills, California and 20 others

Active not recruitingA Study to Determine the Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of ABBV-927 With ABBV-368, Budigalimab (ABBV-181) and/or Chemotherapy in Participants With Locally Advanced or Metastatic Solid TumorsA study evaluating the safety, pharmacokinetics (PK), pharmacodynamics, and preliminary efficacy of ABBV-927 with ABBV-368, Budigalimab (ABBV-181) and/or chemotherapy in…NCT03893955·Springdale, Arkansas and 25 others

CompletedCombination Chemotherapy in Treating Patients With Advanced Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more tumor cells.NCT00041314·Birmingham, Alabama and 78 others

CompletedRadiation Therapy in Treating Patients With Stage I Non-Small Cell Lung Cancer And Lung DysfunctionRATIONALE: Specialized radiation therapy that delivers a high dose of radiation directly to the tumor may kill more tumor cells and cause less damage to normal tissue.NCT00009789·Fort Lauderdale, Florida and 19 others

CompletedA Drug-Interaction Study of Necitumumab (IMC-11F8) in Combination With Gemcitabine-CisplatinThe purpose of this study is to investigate the pharmacokinetics (PK) of necitumumab in combination with gemcitabine-cisplatin in participants with advanced malignant solid tumors…NCT01606748·Scottsdale, Arizona and 3 others

TerminatedGSK1572932A Antigen-Specific Cancer Immunotherapeutic as Adjuvant Therapy in Patients With Non-Small Cell Lung CancerThe purpose of this clinical trial is to demonstrate the benefit of the immunotherapeutic product GSK1572932A when given to patients with Non-Small Cell Lung Cancer, after removal…NCT00480025·Birmingham, Alabama and 619 others

TerminatedA Safety and Tolerability Study of NC762 in Subjects With Advanced or Metastatic Solid TumorsThis research study is studying a new drug, NC762, as a possible treatment for advanced or metastatic solid tumors.NCT04875806·New Haven, Connecticut and 7 others

Not yet recruitingTocilizumab Combined With First-Line Chemo-Immunotherapy in Metastatic Non-Small Cell Lung CancerThis is a Phase 1b/2, multi-site, single-arm, open-label, non-randomized study looking at whether adding tocilizumab to standard treatment for metastatic Non-Small Cell Lung…NCT07889232·Indianapolis, Indiana and 3 others

CompletedTTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced CancersThis is a phase 1/1b study of TTX-030 in combination therapy, an antibody that inhibits CD39 enzymatic activity, leading to accumulation of pro-inflammatory adenosine triphosphate…NCT04306900·Scottsdale, Arizona and 31 others

Active not recruitingTesting the Addition of an Anti-cancer Drug, Berzosertib (M6620, VX-970), to the Usual Treatments (Carboplatin and Gemcitabine) and to Pembrolizumab for Patients With Advanced Squamous Cell Non-small Cell Lung CancerThis phase Ib/II trial studies the best dose of carboplatin when given together with berzosertib, gemcitabine and pembrolizumab and to see how well it works in treating patients…NCT04216316·Los Angeles, California and 33 others

Active not recruitingA Study of Ramucirumab (LY3009806) in Combination With Erlotinib in Previously Untreated Participants With EGFR Mutation-Positive Metastatic NSCLC (RELAY)The main purpose of this study is to evaluate the efficacy and safety of ramucirumab in combination with erlotinib as compared to placebo in combination with erlotinib in…NCT02411448·Los Angeles, California and 105 others

Active not recruitingA Study of Multiple Therapies in Biomarker-selected Participants With Resectable Stages IB-III Non-small Cell Lung Cancer (NSCLC)This trial will evaluate the efficacy and safety of various therapies in participants with Stage IB, IIA, IIB, IIIA, or selected IIIB resectable and untreated NSCLC tumors that…NCT04302025·Los Angeles, California and 23 others

TerminatedEfficacy and Safety Study of Stereotactic Body Radiotherapy (SBRT) With or Without Pembrolizumab (MK-3475) in Adults With Unresected Stage I or II Non-Small Cell Lung Cancer (NSCLC) (MK-3475-867/KEYNOTE-867)The purpose of this study is to assess the efficacy and safety of stereotactic body radiotherapy (SBRT) plus pembrolizumab (MK-3475) in the treatment of adult participants with…NCT03924869·Birmingham, Alabama and 193 others

Active not recruitingU3-1402 in Metastatic or Unresectable Non-Small Cell Lung CancerThis study was designed to evaluate safety and antitumor activity of HER3-DXd in two parts: Dose Escalation and Dose Expansion.NCT03260491·Duarte, California and 36 others

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