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Clareo Health | Lung Cancer Clinical Trials in Pittsburgh | 374 Studies

Clinical Trials Lung CancerPittsburgh

Lung Cancer Clinical Trials in Pittsburgh

Find 374 clinical trials for lung cancer near Pittsburgh, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Pittsburgh

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 261-280 of 374 trials

RecruitingStudy With ABBV-CLS-484 in Participants With Locally Advanced or Metastatic TumorsThe study will assess the safety, PK, PD, and preliminary efficacy of ABBV-CLS-484 as monotherapy and in combination with a PD-1 targeting agent or with a or a vascular…NCT04777994·Tucson, Arizona and 29 others

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Data from ClinicalTrials.govTerms

CompletedCPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced CancersThis is a Phase 1/1b open-label, dose escalation and dose expansion study of CPI-006, a humanized monoclonal antibody (mAb) targeting the CD73 cell-surface ectonucleotidase in…NCT03454451·Tucson, Arizona and 26 others

RecruitingKO-2806 Monotherapy and Combination Therapies in Advanced Solid TumorsThis first-in-human (FIH) dose-escalation and dose-validation/expansion study will assess KO-2806, a farnesyltransferase inhibitor (FTI), as a monotherapy and in combination, in…NCT06026410·Phoenix, Arizona and 37 others

Active not recruitingU3-1402 in Metastatic or Unresectable Non-Small Cell Lung CancerThis study was designed to evaluate safety and antitumor activity of HER3-DXd in two parts: Dose Escalation and Dose Expansion.NCT03260491·Duarte, California and 36 others

CompletedCAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumorsNCT03504488·Tucson, Arizona and 58 others

WithdrawnStudy of Autologous Tumor Infiltrating Lymphocytes (LN-145) In Combo With Durvalumab in Non-Small Cell Lung CancerThis study is a Phase 2, open-label, multicenter study evaluating adoptive cell therapy (ACT) with autologous TIL therapy (LN-145) in combination with Anti-PD-L1 inhibitor…NCT03419559·La Jolla, California and 7 others

CompletedSafety Study of Enoblituzumab (MGA271) in Combination With Pembrolizumab or MGA012 in Refractory CancerThe purpose of this study is to evaluate the safety of enoblituzumab (MGA271) in combination with Keytruda (pembrolizumab) when given to patients with B7-H3-expressing melanoma…NCT02475213·Scottsdale, Arizona and 19 others

CompletedPhase II Study of VS-6063 in Patients With KRAS Mutant Non-Small Cell Lung CancerThis is a Phase II, open-label, multicenter, multi cohort, study of VS-6063 (defactinib), a focal adhesion kinase inhibitor, in patients with KRAS mutant non-small cell lung…NCT01951690·Denver, Colorado and 8 others

CompletedTrastuzumab Plus Chemotherapy in Treating Patients With Advanced Non-small Cell Lung CancerRATIONALE: Monoclonal antibodies can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.NCT00003881·Scottsdale, Arizona and 70 others

CompletedCetuximab in Treating Patients With Recurrent or Stage IIIB or Stage IV Lung CancerRATIONALE: Monoclonal antibodies, such as cetuximab, can block tumor growth in different ways. Some block the ability of tumor cells to grow and spread.NCT00103207·Aurora, Colorado and 156 others

CompletedA Study of Avutometinib (VS-6766) + Defactinib in Recurrent KRAS G12V, Other KRAS and BRAF Non-Small Cell Lung CancerThis study will assess the safety and efficacy of avutometinib (VS-6766) monotherapy or VS-6766 in combination with defactinib in subjects with recurrent Non-small cell lung…NCT04620330·Duarte, California and 44 others

Active not recruitingCrizotinib in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Removed by Surgery and ALK Fusion Mutations (An ALCHEMIST Treatment Trial)This randomized phase III trial studies how well crizotinib works in treating patients with stage IB-IIIA non-small cell lung cancer that has been removed by surgery and has a…NCT02201992·Birmingham, Alabama and 1617 others

UnknownStudy of DN-101 (Calcitriol) and Docetaxel in Subjects Previously Enrolled in Studies DN101-002 or DN101-004The purpose of this study is to monitor the safety of continued DN-101 and docetaxel treatment for subjects previously enrolled in DN101-002 (ASCENT) or DN101-004 (NSCLC) Studies.NCT00285675·Berkeley, California and 12 others

WithdrawnEPIC- Extracorporeal Photopheresis (ECP) for Immune-related ColitisThe photoactivating agent UVADEX (methoxsalen) is used in conjunction with extracorporeal photopheresis (ECP) as an immunomodulatory therapy approved for the treatment of…NCT06646016·Pittsburgh, Pennsylvania

Active not recruitingA Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants With Stage I Adenocarcinoma NSCLC Who Are ctDNA-positive or Have High-risk Pathological FeaturesThis is a Phase III, randomised, open-label, multicentre, global study assessing the efficacy and safety of adjuvant Dato-DXd in combination with rilvegostomig compared with SoC…NCT06564844·Tucson, Arizona and 89 others

UnknownCyberKnife Radiosurgical Treatment of Inoperable Early Stage Non-Small Cell Lung CancerThe purpose of this study is to assess the short and long-term outcomes after CyberKnife stereotactic radiosurgery for early stage non-small cell lung cancer (NSCLC) in patients…NCT00643318·Phoenix, Arizona and 22 others

CompletedGlycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemiplimab.NCT05259696·La Jolla, California and 12 others

RecruitingStudy of NXP900 With Osimertinib in Subjects With Advanced, EGFR-Mutated Non-Small Cell Lung CancerThis is a multi-center, open label, Phase 1b study of NXP900 in combination with osimertinib in subjects with advanced, progressing, EGFR-mutated non-small cell lung cancer (NSCLC)NCT07315113·Calverton, Maryland and 5 others

CompletedCarboplatin and Gemcitabine Combined With Celecoxib and/or Zileuton in Treating Patients With Advanced Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy, such as carboplatin and gemcitabine, work in different ways to stop tumor cells from dividing so they stop growing or die.NCT00070486·Anniston, Alabama and 74 others

Active not recruitingA Study of Novel Anti-cancer Agents in Patients With Previously Untreated NSCLCThis study is designed to determine the efficacy and safety of durvalumab and/or novel oncology therapies, with or without chemotherapy, for first-line Stage IV Non-Small Cell…NCT03819465·Iowa City, Iowa and 40 others

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Other Conditions in Pittsburgh

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