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Clareo Health | Lung Cancer Clinical Trials in Philadelphia | 481 Studies

Clinical Trials Lung CancerPhiladelphia

Lung Cancer Clinical Trials in Philadelphia

Find 481 clinical trials for lung cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Philadelphia

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Showing 81-100 of 481 trials

TerminatedStudy of TPX-0046, A RET/SRC Inhibitor in Adult Subjects With Advanced Solid Tumors Harboring RET Fusions or MutationsA phase 1/2, first-in-human, open-label study to determine the safety, tolerability, PK, and preliminary efficacy of the novel RET/SRC inhibitor TPX-0046 in adult subjects with…NCT04161391·La Jolla, California and 20 others CompletedEvaluation of GLR2007 for Advanced Solid TumorsEvaluation of GLR2007 for Advanced Solid TumorsNCT04444427·Lafayette, Indiana and 3 others Active not recruitingTesting Crizotinib as a Potential Targeted Treatment in Cancers With ROS1 Genetic Changes (MATCH-Subprotocol G)This phase II MATCH treatment trial identifies the effects of crizotinib in patients whose cancer has a genetic change called ROS1 translocation.NCT04439253·Philadelphia, Pennsylvania

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Data from ClinicalTrials.govTerms

CompletedNT-I7 (Efineptakin Alfa) in Combination With Pembrolizumab in Participants With Advanced Solid TumorsThe main purposes of Phase 1b of this study are to determine the following in participants with advanced solid tumors: * Safety and tolerability of NT-I7 in combination with…NCT04332653·Tampa, Florida and 7 others

Active not recruitingA Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815This phase 1 study will investigate the safety, dosing, and initial antitumor activity of JZP815 in participants with advanced or metastatic solid tumors harboring alterations in…NCT05557045·Los Angeles, California and 14 others

CompletedMonoclonal Antibody ABX-EGF in Treating Patients With Renal (Kidney), Prostate, Pancreatic, Non-Small Cell Lung, Colon or Rectal, Esophageal, or Gastroesophageal Junction CancerRATIONALE: Monoclonal antibodies such as ABX-EGF can locate tumor cells and either kill them or deliver tumor-killing substances to them without harming normal cells.NCT00004879·Los Angeles, California and 1 other

Active not recruitingErlotinib Hydrochloride and Cabozantinib-s-Malate Alone or in Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-small Cell Lung CancerThis randomized phase II trial studies how well giving erlotinib hydrochloride and cabozantinib-s-malate alone or in combination works as second or third line therapy in treating…NCT01708954·Scottsdale, Arizona and 355 others

Active not recruitingA Study of Osimertinib With or Without Chemotherapy as 1st Line Treatment in Patients With Mutated Epidermal Growth Factor Receptor Non-Small Cell Lung Cancer (FLAURA2)The reason for the study is to find out if an experimental combination of an oral medication called osimertinib (TAGRISSO®) when used in combination with chemotherapy is more…NCT04035486·Bellflower, California and 152 others

CompletedSafety Study of MGA271 in Refractory CancerThe purpose of this study is to evaluate the safety of MGA271 when given by intravenous (IV) infusion to patients with refractory cancer.NCT01391143·Los Angeles, California and 11 others

Active not recruitingAnvumetostat Alone or in Combination With Other Therapies in Subjects With Advanced Thoracic Tumors With Homozygous MTAP-deletion (Master Protocol) (MTAPESTRY 104).The study aims to determine maximum tolerated dose (MTD) or recommended combination dose of the MTA-cooperative PRMT5 inhibitor Anvumetostat administered in combination with other…NCT06333951·Bakersfield, California and 82 others

RecruitingLung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung CancerThis screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and…NCT03851445·Birmingham, Alabama and 1228 others

RecruitingA Global Phase III Study of Rilvegostomig or Pembrolizumab Monotherapy for First-Line Treatment of PD-L1-high Metastatic Non-small Cell Lung CancerThe purpose of ARTEMIDE-Lung04 is to assess the efficacy and safety of rilvegostomig compared with pembrolizumab monotherapy as 1L treatment in participants with mNSCLC and whose…NCT06868277·La Mesa, California and 303 others

CompletedPrognostic Study of Metastases in Patients With Stage I, Stage II, or Stage III Non-small Cell Lung Cancer That Can Be Removed by SurgeryRATIONALE: Prognostic testing for early signs of metastases may help doctors detect metastases early and plan more effective treatment.NCT00003901·Mobile, Alabama and 57 others

CompletedPhase Ib Study of LDK378 and AUY922 in ALK-rearranged Non-small Cell Lung CancerThe primary purpose of the study is to estimate the maximum tolerated dose of the combination of LDK378 and AUY922.NCT01772797·Aurora, Colorado and 7 others

TerminatedS0819: Carboplatin and Paclitaxel With or Without Bevacizumab and/or Cetuximab in Treating Patients With Stage IV or Recurrent Non-Small Cell Lung CancerThis randomized phase III trial studies carboplatin and paclitaxel to compare how well they work with or without bevacizumab and/or cetuximab in treating patients with stage IV or…NCT00946712·Anniston, Alabama and 797 others

CompletedA Study of Erlotinib Plus Radiotherapy (RT) for Patients With Advanced or Inoperable Non-Small-Cell Lung CancerIt is generally accepted that the presence of chronically hypoxic cells, or tumor cells which do not receive enough oxygen as a result of tumor growth, may be an important cause…NCT00983307·Dunmore, Pennsylvania and 1 other

CompletedSafety Study of Nivolumab With Nab-Paclitaxel Plus or Minus Gemcitabine in Pancreatic Cancer, Nab-Paclitaxel / Carboplatin in Stage IIIB/IV Non-Small Cell Lung Cancer or Nab-Paclitaxel in Recurrent Metastatic Breast CancerThe purpose of this study is to assess safety of nab-paclitaxel based chemotherapy regimens administered prior to and/or in combination with nivolumab in Pancreatic Cancer, Non…NCT02309177·Sacramento, California and 14 others

Active not recruitingTesting the Timing of Pembrolizumab Alone or With Chemotherapy as First Line Treatment and Maintenance in Non-small Cell Lung CancerThis phase III trial studies whether pembrolizumab alone as a first-line treatment, followed by pemetrexed and carboplatin with or without pembrolizumab after disease progression…NCT03793179·Mobile, Alabama and 1093 others

CompletedA Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced MalignanciesThis is a study to determine the maximum tolerated dose (MTD) for CDX-1140 (CD40 antibody), either alone or in combination with CDX-301 (FLT3L), pembrolizumab, or chemotherapy and…NCT03329950·Scottsdale, Arizona and 10 others

Approved for marketingAfatinib Expanded Access ProgramThis is an open-label, multi-center, single-arm trial, designed to provide early access to afatinib and to provide additional information on the safety and efficacy of afatinib in…NCT01649284·Mobile, Alabama and 65 others

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Other Conditions in Philadelphia

Breast Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma