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Clareo Health | Lung Cancer Clinical Trials in Philadelphia | 481 Studies

Clinical Trials Lung CancerPhiladelphia

Lung Cancer Clinical Trials in Philadelphia

Find 481 clinical trials for lung cancer near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 361-380 of 481 trials

CompletedStudy of the Glutaminase Inhibitor CB-839 in Solid TumorsMany tumor cells, in contrast to normal cells, have been shown to require the amino acid glutamine to produce energy for growth and survival.NCT02071862·San Francisco, California and 12 others

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Data from ClinicalTrials.govTerms

CompletedAn Investigational Immuno-therapy Trial of Nivolumab, or Nivolumab Plus Ipilimumab, or Nivolumab Plus Platinum-doublet Chemotherapy, Compared to Platinum Doublet Chemotherapy in Patients With Stage IV Non-Small Cell Lung Cancer (NSCLC)The purpose of this study is to show that Nivolumab, or Nivolumab plus Ipilimumab, or Nivolumab plus Platinum-Doublet Chemotherapy improves progression free survival and/or…NCT02477826·Mobile, Alabama and 289 others

CompletedBinimetinib and Hydroxychloroquine in Patients With Advanced KRAS Mutant Non-Small Cell Lung CancerThis study will evaluate using hydroxychloroquine (HCQ) along with binimetinib as an effective method for treating cancer.NCT04735068·Philadelphia, Pennsylvania

TerminatedStudy of Talabostat and Pemetrexed vs. Pemetrexed in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) After Failure of Platinum-Based ChemotherapyThis Phase 3 study will compare the efficacy of talabostat plus pemetrexed to pemetrexed plus placebo in patients with Stage IIIB/IV NSCLC who have failed a platinum-based…NCT00290017·Huntsville, Alabama and 100 others

CompletedA Study of AT13387 in Patients With Non-Small Cell Lung Cancer (NSCLC) Alone and in Combination With CrizotinibThe purpose of the study is to evaluate safety and efficacy of AT13387 Alone and in Combination with Crizotinib in the Treatment of Non-small Cell Lung Cancer.NCT01712217·Scottsdale, Arizona and 64 others

CompletedImproving Clinical Trial Awareness in NSCLC: Pilot Testing A Novel Healthcare IT Platform for Incorporating Education at the Point of CareThe objective of this study is to 1) evaluate the impact of a novel individualized care planning/ educational technology (the On Q Care Planning System or CPS) on oncology patient…NCT02558998·Philadelphia, Pennsylvania

CompletedSurgery With or Without Internal Radiation Therapy in Treating Patients With Stage I Non-Small Cell Lung CancerThis randomized phase III trial studies surgery and internal radiation therapy to see how well they work compared to surgery alone in treating patients with stage I non-small cell…NCT00107172·Scottsdale, Arizona and 37 others

CompletedPhase II Study Alimta and Gemzar + Avastin as First Line Chemotherapy for Elderly Patients With Stage IIIB/IV NSCLCThe primary objective is to determine the progression free survival with pemetrexed, and gemcitabine plus bevacizumab as first-line chemotherapy in elderly patients with Stage…NCT00517595·Waterbury, Connecticut and 9 others

Active not recruitingA Study of JZP815 Oral Capsules in Adult Participants With Advanced or Metastatic Solid Tumors Harboring Mitogen Activated Protein Kinase (MAPK) Pathway Alterations to Investigate the Safety, Dosing, and Antitumor Activity of JZP815This phase 1 study will investigate the safety, dosing, and initial antitumor activity of JZP815 in participants with advanced or metastatic solid tumors harboring alterations in…NCT05557045·Los Angeles, California and 14 others

CompletedCisplatin Plus Vinorelbine With or Without Tirapazamine in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00017459·Los Angeles, California and 41 others

CompletedCelecoxib and Radiation Therapy in Treating Patients With Locally Advanced Non-Small Cell Lung CancerRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00046839·Colorado Springs, Colorado and 43 others

Active not recruitingErlotinib Hydrochloride and Cabozantinib-s-Malate Alone or in Combination as Second or Third Line Therapy in Treating Patients With Stage IV Non-small Cell Lung CancerThis randomized phase II trial studies how well giving erlotinib hydrochloride and cabozantinib-s-malate alone or in combination works as second or third line therapy in treating…NCT01708954·Scottsdale, Arizona and 355 others

CompletedA Study Comparing Sequential Satraplatin & Erlotinib to Erlotinib in Unresectable Stage 3/4 Non-small-cell Lung Cancer (NSCLC)Patients ≥ 70 years of age with locally advanced unresectable or metastatic non-small cell lung cancer (NSCLC) frequently do not receive systemic cytotoxic chemotherapy due to…NCT00370383·Anaheim, California and 15 others

Active not recruitingAZD9291 in Combination With Ascending Doses of Novel TherapeuticsThe purpose of this study is to determine the safety, tolerability and preliminary anti-tumour activity of AZD9291 when given together with AZD6094 or selumetinib in patients with…NCT02143466·Atlanta, Georgia and 41 others

CompletedABR-217620 in Patients With Advanced Non-Small Cell Lung Cancer, Renal Clear Cell Carcinoma or Pancreatic CancerThe drug ABR-217620 is a combination of two proteins, one that recognizes tumor cells and one that triggers an attack on the tumor cells by activating some white blood cells…NCT00056537·Philadelphia, Pennsylvania and 2 others

CompletedRadiation Therapy in Treating Patients With Non-small Cell Lung CancerRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00002577·Birmingham, Alabama and 241 others

CompletedEffects of Matuzumab in Combination With Pemetrexed for the Treatment of Advanced Lung CancerThis open-label, multicenter, randomized, controlled, Phase II study is planned to answer questions about how the drug, matuzumab (EMD 72000), works and is part of an effort aimed…NCT00111839·Tucson, Arizona and 57 others

CompletedAssess Efficacy and Safety of AZD6244 in Combination With Docetaxel in Patients Receiving Second Line Non Small Cell Lung Cancer Treatment.The purpose of this study is to treat patients with locally advanced or metastatic NSCLC with a combination therapy of selumetinib and two different doses of docetaxel 75mg/m2 or…NCT01750281·Santa Monica, California and 67 others

CompletedStudy of Nivolumab (BMS-936558) in Combination With Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, Carboplatin/Paclitaxel, Bevacizumab Maintenance, Erlotinib, Ipilimumab or as Monotherapy in Subjects With Stage IIIB/IV Non-small Cell Lung Cancer (NSCLC) (CheckMate 012)* The study is evaluating the safety and tolerability of Nivolumab (BMS-936558) when combined with three platinum-based doublet chemotherapy regimens (Cisplatin/Gemcitabine…NCT01454102·Los Angeles, California and 11 others

CompletedStudy of NOV-002 in Combination With Chemotherapy to Treat Lung CancerThe purpose of this clinical trial is to find out whether or not the combination of NOV-002 with chemotherapy (paclitaxel and carboplatin) is better at improving overall survival…NCT00347412·Muscle Shoals, Alabama and 74 others

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