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Clareo Health | Lung Cancer Clinical Trials in Pennsylvania | 893 Studies

Clinical Trials Lung CancerPennsylvania

Lung Cancer Clinical Trials in Pennsylvania

Find 893 clinical trials for lung cancer near Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

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Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 161-180 of 893 trials

CompletedA Study of CDX-1140 (CD40) as Monotherapy or in Combination in Patients With Advanced MalignanciesThis is a study to determine the maximum tolerated dose (MTD) for CDX-1140 (CD40 antibody), either alone or in combination with CDX-301 (FLT3L), pembrolizumab, or chemotherapy and…NCT03329950·Scottsdale, Arizona and 10 others TerminatedA Study of BMS-986442 With Nivolumab With or Without Chemotherapy in Solid Tumors and Non-small Cell Lung CancerThe purpose of this study is to evaluate BMS-986442 in combination with nivolumab (with or without chemotherapy) for its antitumor efficacy and benefit to participants.NCT05543629·Phoenix, Arizona and 31 others

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Data from ClinicalTrials.govTerms

Active not recruitingPhase 2 Platform Study in Patients With Advanced Non-Small Lung Cancer Who Progressed on First-Line Osimertinib Therapy (ORCHARD)Phase 2 Platform Study in Patients with Advanced Non-Small Lung Cancer who progressed on First-Line Osimertinib Therapy.NCT03944772·Duarte, California and 46 others

CompletedSafety Study of Nivolumab to Treat Advanced or Metastatic Non-small Cell Lung CancerA study to evaluate the safety of Nivolumab in participants with advanced or metastatic non-small cell lung cancerNCT03090737·Birmingham, Alabama and 16 others

TerminatedNGS Screening Protocol to Detect Mutation of KEAP1 or NRF2/NFE2L2 Genes for the KEAPSAKE (CX-839-014) TrialThis is a multicenter screening protocol designed to identify patients with NSCLC who have tumor mutations in the KEAP1 or NRF2/NFE2L2 genes in order to determine potential…NCT04698681·Daphne, Alabama and 62 others

Active not recruitingA Study of Abemaciclib (LY2835219) in Participants With Previously Treated KRAS Mutated Lung CancerThe main purpose of this study is to evaluate how safe and effective the study drug known as abemaciclib is in participants with lung cancer.NCT02152631·Fayetteville, Arkansas and 230 others

CompletedStudy of Oral cMET Inhibitor INC280 in Patients With EGFR Wild-type (wt), Advanced Non-small Cell Lung Cancer (NSCLC) (Geometry Mono-1)Study to evaluate the efficacy and safety of capmatinib as a single-agent treatment for subjects with advanced/metastatic (stage IIIB or IV) non-small cell lung cancer (NSCLC) who…NCT02414139·Long Beach, California and 94 others

RecruitingA Study Evaluating FMC-376 in Participants With KRAS G12C Mutated Solid TumorsThe goal of this clinical trial is to evaluate FMC-376 in participants with advanced solid tumors with KRAS G12C mutations.NCT06244771·La Jolla, California and 25 others

RecruitingRadiotherapy to Block Oligoprogression In Metastatic Non-Small-Cell Lung CancerThis study is being done to answer the following question: Can the chance of lung cancer growing or spreading be lowered by adding targeted radiotherapy to the usual combination…NCT06686771·Phoenix, Arizona and 74 others

TerminatedStudy of Oral Mifepristone as Salvage Therapy in Patients With Advanced or Metastatic Non-Small Cell Lung CancerThis is a non-randomized, multicenter, single-stage phase II study of mifepristone in patients with advanced or metastatic NSCLC who have failed two or more previous chemotherapy…NCT02642939·Melrose Park, Pennsylvania

CompletedEffects of Matuzumab in Combination With Pemetrexed for the Treatment of Advanced Lung CancerThis open-label, multicenter, randomized, controlled, Phase II study is planned to answer questions about how the drug, matuzumab (EMD 72000), works and is part of an effort aimed…NCT00111839·Tucson, Arizona and 57 others

TerminatedA Study Of Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley)This is a Phase 1b/2 dose-optimization study to evaluate safety, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of avelumab (MSB0010718C) in combination…NCT02554812·Encinitas, California and 87 others

Active not recruitingOsimertinib With or Without Bevacizumab in Treating Patients With EGFR Positive Non-small Cell Lung Cancer and Brain MetastasesThis phase II trial studies how well osimertinib with or without bevacizumab works in treating patients with EGFR positive non-small cell lung cancer that has spread to the brain…NCT02971501·Los Angeles, California and 17 others

CompletedPh1b/2 Dose-Escalation Study of Entinostat With Pembrolizumab in Non-small Cell Lung Cancer (NSCLC) With Expansion Cohorts in NSCLC, Melanoma, and Colorectal Cancer (CRC)The purpose of this study is to determine the safety and tolerability of entinostat used in combination with pembrolizumab in participants with NSCLC.NCT02437136·New Haven, Connecticut and 10 others

TerminatedImmunization of Patients With Non Small Cell Lung Cancer (NSCLC)The study of the vaccine will proceed in two stages after the method of Simon (102). In the first stage, 15 patients will be accrued and treated.NCT00793208·Pittsburgh, Pennsylvania and 1 other

RecruitingPhase I Study of Tolododekin Alfa (ANK-101) in Advanced Solid TumorsThis is a Phase 1, multicenter, open-label dose escalation study to determine the safety and tolerability of intratumoral (IT) injection of tolododekin alfa (ANK-101) in…NCT06171750·Bethesda, Maryland and 4 others

RecruitingA Study to Evaluate the Efficacy of Pumitamig Versus Pembrolizumab in Participants With Previously Untreated Advanced Non-Small Cell Lung Cancer and PD-L1 ≥ 50%. (ROSETTA Lung-202)The purpose of this study is to evaluate the efficacy of Pumitamig versus Pembrolizumab in participants with previously untreated advanced Non-Small Cell Lung Cancer and PD-L1 ≥…NCT07361510·Daphne, Alabama and 283 others

TerminatedPhotodynamic Therapy in Treating Patients With Resectable Non-Small Cell Lung Cancer That Has Spread to the PleuraRATIONALE: Photodynamic therapy uses a drug, such as porfimer sodium, that is absorbed by tumor cells. The drug becomes active when it is exposed to light.NCT00601848·Philadelphia, Pennsylvania

RecruitingTargeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer.NCT06116682·Jonesboro, Arkansas and 247 others

CompletedPemetrexed Disodium Plus Gemcitabine in Treating Patients With Locally Advanced or Metastatic Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00022646·Scottsdale, Arizona and 21 others

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