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Clareo Health | Lung Cancer Clinical Trials in Pennsylvania | 893 Studies

Clinical Trials Lung CancerPennsylvania

Lung Cancer Clinical Trials in Pennsylvania

Find 893 clinical trials for lung cancer near Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 421-440 of 893 trials

RecruitingGEMINI-NSCLC: NSCLC Biomarker StudyGEMINI NSCLC Study is a non-interventional study that will be collecting clinical and molecular health information from patients with NSCLC who will receive longitudinal blood…NCT05236114·Birmingham, Alabama and 57 others

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Data from ClinicalTrials.govTerms

CompletedIntratumoral Gene Mediated Cytotoxic Immunotherapy in Patients With Resectable Non-Small Cell Lung CancerThis is a phase I dose escalation study of CAN-2409 plus prodrug in patients with non-small cell lung cancer (NSCLC).NCT03131037·Philadelphia, Pennsylvania

CompletedCombination Chemotherapy and Computer-Planned Radiation Therapy in Treating Patients With Unresectable Stage III Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00033553·Anniston, Alabama and 73 others

CompletedA Trial of Pembrolizumab in Combination With Chemotherapy and Radiotherapy in Stage III NSCLC (KEYNOTE-799, MK-3475-799)This is a trial in adult participants with unresectable, locally advanced, Stage III non-small cell lung cancer (NSCLC) treated with pembrolizumab in combination with platinum…NCT03631784·Santa Rosa, California and 55 others

UnknownTissue Collection Study for Patients With Non-Small Cell Lung Cancer With Resectable DiseaseA 15-gene lung signature was created to identify predictive and prognostic biomarkers for Non-Small Cell Lung Cancer (NSCLC) patients.NCT01450553·Birmingham, Alabama and 6 others

Active not recruitingA Study of Amivantamab and Lazertinib Combination Therapy Versus Osimertinib in Locally Advanced or Metastatic Non-Small Cell Lung CancerThe purpose of this study is to assess the efficacy of the amivantamab and lazertinib combination, compared with osimertinib, in participants with epidermal growth factor receptor…NCT04487080·Goodyear, Arizona and 268 others

CompletedStereotactic Radiation Therapy With or Without Whole-Brain Radiation Therapy in Treating Patients With Brain MetastasesRATIONALE: Stereotactic radiation therapy can send x-rays directly to the tumor and cause less damage to normal tissue.NCT00377156·Phoenix, Arizona and 63 others

CompletedCarboplatin and Gemcitabine Combined With Celecoxib and/or Zileuton in Treating Patients With Advanced Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy, such as carboplatin and gemcitabine, work in different ways to stop tumor cells from dividing so they stop growing or die.NCT00070486·Anniston, Alabama and 74 others

Active not recruitingA Study of Safety and Efficacy of KFA115 Alone and in Combo With Pembrolizumab in Patients With Select Advanced CancersThe purpose of this study is to characterize the safety and tolerability of KFA115 and KFA115 in combination with pembrolizumab in patients with select advanced cancers, and to…NCT05544929·Boston, Massachusetts and 18 others

RecruitingStudy of Healthy Donor FMT (hdFMT) and Pembrolizumab in Relapsed/Refractory (R/R) PD-L1 Positive NSCLCThis study is to determine if Healthy Donor FMT (hdFMT) improves the body's ability to fight cancer in patients with relapsed/refractory PD-L1 Positive NSCLC.NCT05669846·Pittsburgh, Pennsylvania

TerminatedGenetic Predictors of Benefit to PembrolizumabThe primary objective is to determine if mutation load underlies sensitivity to pembrolizumab alone and in combination with chemotherapy.NCT02710396·New York, New York and 1 other

TerminatedMulticenter Study of Rociletinib Administered to Patients With Previously Treated Mutant EGFR Non-small Cell Lung CancerThe purpose of this study is to evaluate the safety and anti-tumor effect of rociletinib.NCT02147990·Alhambra, California and 90 others

Active not recruitingA Study Evaluating the Efficacy and Safety of Multiple Therapies in Cohorts of Participants With Locally Advanced, Unresectable, Stage III Non-Small Cell Lung Cancer (NSCLC)This study will evaluate the efficacy and safety of multiple therapies in participants with locally advanced, unresectable, Stage III NSCLC with eligible biomarker status as…NCT05170204·Tigard, Oregon and 44 others

CompletedIloprost in Preventing Lung Cancer in Patients at High Risk for This DiseaseRATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. Iloprost may be effective in preventing lung cancer.NCT00084409·Aurora, Colorado and 5 others

CompletedTTX-030 in Combination With Immunotherapy and/or Chemotherapy in Subjects With Advanced CancersThis is a phase 1/1b study of TTX-030 in combination therapy, an antibody that inhibits CD39 enzymatic activity, leading to accumulation of pro-inflammatory adenosine triphosphate…NCT04306900·Scottsdale, Arizona and 31 others

TerminatedPilot Immunotherapy Study With Letetresgene Autoleucel (Lete-cel, GSK3377794)T-cells in New York Esophageal Squamous Cell Carcinoma-1 (NY-ESO-1)/ LAGE-1a-positive Advanced Non-small Cell Lung Cancer (NSCLC) Either Alone or in Combination With PembrolizumabThis trial will evaluate safety and tolerability of letetresgene autoleucel (GSK3377794) with or without pembrolizumab in participants with non-small cell lung cancer.NCT03709706·Duarte, California and 30 others

Active not recruitingA Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants With Stage I Adenocarcinoma NSCLC Who Are ctDNA-positive or Have High-risk Pathological FeaturesThis is a Phase III, randomised, open-label, multicentre, global study assessing the efficacy and safety of adjuvant Dato-DXd in combination with rilvegostomig compared with SoC…NCT06564844·Tucson, Arizona and 89 others

CompletedM7824 Versus Pembrolizumab as a First-line (1L) Treatment in Participants With Programmed Death-ligand 1 (PD-L1) Expressing Advanced Non-small Cell Lung Cancer (NSCLC)The purpose of the study is to evaluate the efficacy and safety of bintrafusp alfa (M7824) compared with pembrolizumab in participants with advanced NSCLC with high PD-L1-tumor…NCT03631706·Huntsville, Alabama and 118 others

CompletedStudy of Nivolumab (BMS-936558) in Patients With Advanced or Metastatic Squamous Cell Nonsmall-cell Lung Cancer Who Have Received At Least 2 Prior Systemic RegimensThe purpose of the study is to assess the objective response rate (change in tumor size from baseline) in patients with advanced or metastatic squamous cell nonsmall-cell lung…NCT01721759·Sacramento, California and 32 others

CompletedStudy Comparing Veliparib Plus Carboplatin and Paclitaxel Versus Placebo Plus Carboplatin and Paclitaxel in Previously Untreated Advanced or Metastatic Squamous Non-Small Cell Lung CancerThe purpose of this study is to evaluate the safety and efficacy of the addition of veliparib plus carboplatin and paclitaxel versus the addition of placebo plus carboplatin and…NCT02106546·Jonesboro, Arkansas and 224 others

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