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Clareo Health | Lung Cancer Clinical Trials in Pennsylvania | 893 Studies

Clinical Trials Lung CancerPennsylvania

Lung Cancer Clinical Trials in Pennsylvania

Find 893 clinical trials for lung cancer near Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 301-320 of 893 trials

Active not recruitingTesting the Addition of an Anti-cancer Drug, Berzosertib (M6620, VX-970), to the Usual Treatments (Carboplatin and Gemcitabine) and to Pembrolizumab for Patients With Advanced Squamous Cell Non-small Cell Lung CancerThis phase Ib/II trial studies the best dose of carboplatin when given together with berzosertib, gemcitabine and pembrolizumab and to see how well it works in treating patients…NCT04216316·Los Angeles, California and 33 others

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Data from ClinicalTrials.govTerms

CompletedPhase II Study of VS-6063 in Patients With KRAS Mutant Non-Small Cell Lung CancerThis is a Phase II, open-label, multicenter, multi cohort, study of VS-6063 (defactinib), a focal adhesion kinase inhibitor, in patients with KRAS mutant non-small cell lung…NCT01951690·Denver, Colorado and 8 others

RecruitingA Study to Assess Adverse Events and Change in Disease Activity of Intravenously (IV) Infused ABBV-324 in Adult Participants With Hepatocellular Cancer (HCC) or Squamous-Cell Non-Small Cell Lung Cancer (LUSC)HCC is a common cancer worldwide and a leading cause of cancer-related death.NCT06858813·Duarte, California and 21 others

TerminatedStudy of Nanrilkefusp Alfa Alone and With Pembrolizumab in Adult Patients With Advanced/Metastatic Solid TumorsA multicenter open-label phase 1/1b study to evaluate the safety and preliminary efficacy of nanrilkefusp alfa as monotherapy and in combination with pembrolizumab in patients…NCT04234113·New Haven, Connecticut and 11 others

CompletedStudy of PX-866 and Docetaxel in Solid TumorsPhase 1: To determine the maximally tolerated dose (MTD) or recommended dose (RD) and any potential efficacy of PX-866 in combination with docetaxel in patients with solid tumors.NCT01204099·Birmingham, Alabama and 32 others

Active not recruitingA Study to Investigate Safety and Tolerability of TransCon IL-2 β/γ Alone or in Combination With Pembrolizumab and/or TransCon TLR7/8 Agonist or Other Anticancer Therapies in Adult Participants With Locally Advanced or Metastatic Solid Tumor MalignanciesTransCon IL-2 β/γ is an investigational drug being developed for treatment of locally advanced or metastatic solid tumors.NCT05081609·Los Angeles, California and 67 others

RecruitingA Global Phase III Study of Rilvegostomig or Pembrolizumab Plus Chemotherapy for First-Line Treatment of Locally Advanced or Metastatic Squamous Non-small Cell Lung Cancer (NSCLC)The purpose of ARTEMIDE-Lung02 is to assess the efficacy and safety of rilvegostomig in combination with platinum-based chemotherapy for the first-line (1L) treatment of patients…NCT06692738·Tucson, Arizona and 327 others

RecruitingLUNAR-2: TTFields With Pembrolizumab + Platinum-based Chemotherapy for Metastatic NSCLCThis study, known as LUNAR-2, aims to investigate the effectiveness and safety of using TTFields, delivered by the NovoTTF-200T device, concomitantly administered with…NCT06216301·Birmingham, Alabama and 97 others

CompletedRadiofrequency Ablation During Surgery in Treating Patients With Non-Small Cell Lung CancerRATIONALE: Radiofrequency ablation uses high-frequency electric current to kill tumor cells. Combining radiofrequency ablation with surgery may kill more tumor cells.NCT00039507·Philadelphia, Pennsylvania

TerminatedCarboplatin And Paclitaxel With Or Without CP-751, 871 (An IGF-1R Inhibitor) For Advanced NSCLC Of Squamous, Large Cell And Adenosquamous Carcinoma HistologyDetermine whether the addition of CP- 751,871 in combination with paclitaxel plus carboplatin prolongs survival in patients with locally advanced (Stage IIIB with pleural…NCT00596830·Florence, Alabama and 279 others

Active not recruitingAssess Efficacy & Safety of Selumetinib in Combination With Docetaxel in Patients Receiving 2nd Line Treatment for v-Ki-ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) Positive NSCLCThe purpose of this study is to assess the efficacy of selumetinib in combination with docetaxel (75mg/m2) vs placebo in combination with docetaxel (75mg/m2) in patients with…NCT01933932·Aurora, Colorado and 196 others

CompletedA Study to Evaluate the Efficacy and Safety of Anamorelin HCl for the Treatment of Malignancy Associated Weight Loss and Anorexia in Adult Patients With Advanced Non-Small Cell Lung Cancer (NSCLC)The goal of this clinical trial was to compare the efficacy and safety of anamorelin HCl (the investigational drug) to that of placebo (tablet with no drug) in patients with…NCT03743051·Tucson, Arizona and 71 others

RecruitingA Study of Targeted Post-Surgery Radiation Therapy for Non-Small Cell Lung Cancer With Remaining Lymph Node Cancer After TreatmentThis phase II trial compares the effect of intensity-modulated post-operative radiation therapy (I²-PORT) followed by standard of care therapy (chemotherapy or immunotherapy) to…NCT07293247·Jonesboro, Arkansas and 96 others

CompletedErlotinib Plus Tivantinib (ARQ 197) Versus Single Agent Chemotherapy in Locally Advanced or Metastatic Non-Small Cell Lung CancerThe purpose of this study is to evaluate progression-free survival among subjects with KRAS mutation positive Non-Small Cell Lung Cancer (NSCLC) treated with erlotinib plus…NCT01395758·Stanford, California and 12 others

Active not recruitingPhase 1/2 Trial of Gavo-cel (TC-210) in Patients With Advanced Mesothelin-Expressing CancerGavocabtagene autoleucel (gavo-cel; TC-210) is a novel cell therapy that consists of autologous genetically engineered T cells expressing a single-domain antibody that recognizes…NCT03907852·San Francisco, California and 10 others

RecruitingJoLT-Ca Sublobar Resection (SR) Versus Stereotactic Ablative Radiotherapy (SAbR) for Lung CancerTo Determine if SAbR improves survival over SR in High Risk Operable Stage I NSCLCNCT02468024·La Jolla, California and 49 others

TerminatedNaloxegol in Treating Patients With Stage IIIB-IV Non-small Cell Lung CancerThis randomized pilot clinical trial studies the side effects and best dose of naloxegol and to see how well it works in treating patients with stage IIIB-IV non-small cell lung…NCT03087708·Anchorage, Alaska and 659 others

TerminatedA Study of ALRN-6924 for the Prevention of Chemotherapy-induced Side Effects (Chemoprotection)This is a Phase 1b, multicenter, 2-part study of ALRN-6924 for the prevention of chemotherapy-induced side effects.NCT04022876·Kingman, Arizona and 27 others

Active not recruitingA Study to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-6036 Alone or in Combination in Participants With Advanced or Metastatic Solid Tumors With a KRAS G12C MutationThis is a Phase I dose-escalation and dose-expansion study that will evaluate the safety, pharmacokinetics (PK), and preliminary activity of GDC-6036 in patients with advanced or…NCT04449874·Duarte, California and 62 others

Active not recruitingA Study of Ramucirumab (LY3009806) in Combination With Erlotinib in Previously Untreated Participants With EGFR Mutation-Positive Metastatic NSCLC (RELAY)The main purpose of this study is to evaluate the efficacy and safety of ramucirumab in combination with erlotinib as compared to placebo in combination with erlotinib in…NCT02411448·Los Angeles, California and 105 others

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