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Clareo Health | Lung Cancer Clinical Trials in Pennsylvania | 893 Studies

Clinical Trials Lung CancerPennsylvania

Lung Cancer Clinical Trials in Pennsylvania

Find 893 clinical trials for lung cancer near Pennsylvania. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Pennsylvania

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 261-280 of 893 trials

RecruitingAMG 410 Alone and in Combination With Other Agents in Participants With KRAS Altered Advanced or Metastatic Solid TumorsThe purpose of this first-in-human study is to evaluate the safety, tolerability, pharmacokinetics (PK), pharmacodynamics (PD), and preliminary efficacy of AMG 410 when…NCT07094113·Duarte, California and 38 others

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Data from ClinicalTrials.govTerms

TerminatedA Phase 2, Study of Ficlatuzumab Plus Erlotinib vs. Placebo Plus Erlotinib in Subjects With Previously Untreated Metastatic, EGFR-mutated NSCLC and BDX004 Positive LabelPhase 2 multicenter, controlled, randomized, double-blind study to evaluate the efficacy and safety of ficlatuzumab versus placebo when administered with erlotinib in subjects…NCT02318368·Fresno, California and 46 others

RecruitingStudy of Izalontamab Brengitecan (BMS-986507) Versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer After Failure of EGFR TKI Therapy (IZABRIGHT-Lung01)A Study of Izalontamab Brengitecan (BMS-986507) versus Platinum-Pemetrexed for EGFR-mutated Non-small Cell Lung Cancer after failure of EGFR TKI TherapyNCT07100080·Irvine, California and 184 others

CompletedCAB-ROR2-ADC Safety and Efficacy Study in Patients With TNBC or Head & Neck Cancer (Ph1) and NSCLC or Melanoma (Ph2)The objective of this study is to assess safety and efficacy of CAB-ROR2-ADC in solid tumorsNCT03504488·Tucson, Arizona and 58 others

CompletedAn Observational Pilot Study Evaluating the Feasibility of Conducting Genome-Wide Association Studies Utilizing Subject Provided Information in Subjects With Locally Recurrent or MBC, MCRC, MNSCLC, RGBM or MRCC Treated With Avastin (Bevacizumab) (InVite)This pilot, non-interventional, observational, Web-based, prospective cohort study is designed to collect self-reported safety and effectiveness and genetic data from subjects…NCT01598597·Many Locations, Alabama and 49 others

CompletedSafety, Tolerability, Immunogenicity, and Antitumor Activity of GEN-009 Adjuvanted VaccineIn this study, Genocea is evaluating an investigational, personalized adjuvanted vaccine, GEN-009, that is being developed for the treatment of patients with solid tumors.NCT03633110·La Jolla, California and 10 others

CompletedSorafenib in Treating Patients With Refractory Non-Small Cell Lung CancerRATIONALE: Preclinical studies indicate that sorafenib is a potent inhibitor of Raf kinase in vitro and in vivo, with significant dose-dependent, anti-tumor activity in four…NCT00064350·Stanford, California and 140 others

Active not recruitingTesting the Addition of an Anti-cancer Drug, BAY 1895344, to the Usual Chemotherapy Treatment (Cisplatin, or Cisplatin and Gemcitabine) for Advanced Solid Tumors With Emphasis on Urothelial CancerThis phase I trial identifies the best dose, possible benefits and/or side effects of BAY 1895344 in combination with chemotherapy in treating patients with solid tumors or…NCT04491942·Sacramento, California and 7 others

CompletedPhase I/II Eval Safety & Prelim Activity Nivolumab Comb W/Vorolanib Pts W/Refractory Thoracic TumorsThis is a two-agent, open-label, non-randomized, Phase 1/2 dose escalation and dose expansion study of combinatorial oral vorolanib plus infusional nivolumab in patients with…NCT03583086·Palo Alto, California and 6 others

CompletedA Study of AT13387 in Patients With Non-Small Cell Lung Cancer (NSCLC) Alone and in Combination With CrizotinibThe purpose of the study is to evaluate safety and efficacy of AT13387 Alone and in Combination with Crizotinib in the Treatment of Non-small Cell Lung Cancer.NCT01712217·Scottsdale, Arizona and 64 others

RecruitingStudy to Evaluate Adverse Events and Efficacy of Intravenous (IV) Telisotuzumab Adizutecan in Combination With a PD-1 Immune Checkpoint Inhibitor in Adult Participants With Advanced or Metastatic Non-Squamous NSCLC With No Prior Treatment for Advanced Disease, and No Actionable Genomic AlterationsNon small cell lung carcinoma (NSCLC) is the most frequently occurring histologic subtype of lung cancer and is the leading cause of cancer-related deaths worldwide.NCT06772623·Phoenix, Arizona and 122 others

No longer availableExpanded Access For Lorlatinib For Patients With Non Small Cell Lung Cancer ALK Positive or ROS1 PositiveThis expanded access study has being designed following a demand from the FDA, given the increase in the number of request for single patient INDs for lorlatinibNCT03178071·Sedona, Arizona and 48 others

TerminatedQUILT-2.017: Phase 1b/2 Study of AMG 479 in Combination With Paclitaxel and Carboplatin for 1st Line Treatment of Advanced Squamous Non-Small Cell Lung CancerThis is a global, multicenter, 2-part, open-label phase 1b and single-arm phase 2 study designed to evaluate the safety and efficacy of AMG 479 in combination with paclitaxel and…NCT00807612·Fayetteville, Arkansas and 24 others

CompletedA Study of a Personalized Cancer Vaccine Targeting Shared NeoantigensThe purpose of this study is to evaluate the dose, safety, immunogenicity and early clinical activity of GRT-C903 and GRT-R904, a neoantigen-based therapeutic cancer vaccine, in…NCT03953235·Phoenix, Arizona and 11 others

TerminatedStudy of INBRX-105 and INBRX-105 With Pembrolizumab in Patients With Solid Tumors Including Head and Neck CancerThis is a first-in-human, open-label, nonrandomized, four-part trial to determine the safety profile and identify the maximum tolerated dose (MTD) and/or recommended Phase 2 dose…NCT03809624·Scottsdale, Arizona and 22 others

RecruitingAPL-101 Study of Subjects With NSCLC With c-Met EXON 14 Skip Mutations and c-Met Dysregulation Advanced Solid TumorsTo assess: * efficacy of APL-101 as monotherapy for the treatment of NSCLC harboring MET Exon 14 skipping mutations, NSCLC harboring MET amplification, solid tumors harboring MET…NCT03175224·Los Angeles, California and 34 others

CompletedEffect of GTx-024 on Muscle Wasting in Patients With Non-Small Cell Lung Cancer (NSCLC) on First Line PlatinumThe purpose of this study is to determine if the investigational drug GTx-024 can help patients with non small cell lung cancer increase physical function and maintain or gain…NCT01355497·Birmingham, Alabama and 29 others

TerminatedStudy of Talabostat and Pemetrexed vs. Pemetrexed in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) After Failure of Platinum-Based ChemotherapyThis Phase 3 study will compare the efficacy of talabostat plus pemetrexed to pemetrexed plus placebo in patients with Stage IIIB/IV NSCLC who have failed a platinum-based…NCT00290017·Huntsville, Alabama and 100 others

CompletedRadiation Therapy in Preventing Central Nervous System (CNS) Metastases in Patients With Non-Small Cell Lung CancerRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00048997·Phoenix, Arizona and 13 others

Active not recruitingErlotinib Hydrochloride in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer That Has Been Completely Removed by Surgery (An ALCHEMIST Treatment Trial)This phase III ALCHEMIST trial studies how well erlotinib hydrochloride compared to observation works in treating patients with stage IB-IIIA non-small cell lung cancer that has…NCT02193282·Birmingham, Alabama and 1406 others

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