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Clareo Health | Lung Cancer Clinical Trials in North Carolina | 172 Studies

Clinical Trials Lung CancerNorth Carolina

Lung Cancer Clinical Trials in North Carolina

Find 172 clinical trials for lung cancer near North Carolina. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in North Carolina

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 141-160 of 172 trials

CompletedRadiofrequency Ablation in Treating Patients With Stage I Non-Small Cell Lung CancerThis pilot clinical trial studies how well radiofrequency ablation works in treating patients with stage IA non-small cell lung cancer.NCT00109876·Birmingham, Alabama and 16 others CompletedProteomic Profiling in Diagnosing Non-Small Cell Lung Cancer in Patients Who Are Undergoing Lung Resection for Suspicious Stage I Lung LesionsRATIONALE: Evaluating specific proteins in the blood may be an effective and noninvasive procedure to help doctors determine if a patient has early non-small cell lung cancer.NCT00077324·Birmingham, Alabama and 72 others

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Data from ClinicalTrials.govTerms

RecruitingA Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung CancerThe purpose of this study is to assess if adding LY3537982 (olomorasib) in combination with standard of care anti-cancer drugs is more effective than standard of care in…NCT06119581·Huntsville, Alabama and 417 others

CompletedStudy of Avutometinib (VS-6766) + Adagrasib in KRAS G12C NSCLC PatientsThis study will assess the safety and efficacy of avutometinib (VS-6766) in combination with adagrasib in patients with G12C Non-Small Cell Lung Cancer (NSCLC) who have been…NCT05375994·San Francisco, California and 7 others

CompletedS0636: Erlotinib and Bevacizumab in Never-Smokers With Stage IIIB or Stage IV Primary Non-Small Cell Lung CancerRATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00445848·Antioch, California and 152 others

TerminatedStudy to Investigate DRP-104 in Adults With Advanced Solid TumorsThe purpose of this study is to characterize the safety, tolerability, pharmacokinetics, pharmaco-dynamics and preliminary anti-tumor activity of DRP-104 (sirpiglenastat)…NCT04471415·Scottsdale, Arizona and 21 others

TerminatedA Phase 3 Study of Ganetespib in Combination With Docetaxel Versus Docetaxel Alone in Patients With Advanced NSCLCThe purpose of this study is to determine whether combining ganetespib (STA-9090) with docetaxel is more effective than docetaxel alone in the treatment of patients with advanced…NCT01798485·Flagstaff, Arizona and 266 others

RecruitingA Study to Assess Efficacy and Safety of Pembrolizumab With or Without Sacituzumab Tirumotecan (MK- 2870) in Adult Participants With Resectable Non Small Cell Lung Cancer (NSCLC) Not Achieving Pathological Complete Response (pCR) (MK-2870-019)This study will assess if adding sacituzumab tirumotecan with pembrolizumab after surgery is effective in treating NSCLC for participants not achieving pathological complete…NCT06312137·Little Rock, Arkansas and 269 others

CompletedUtility of Routine Cervical Mediastinoscopy in Clinical Stage I Non-Small Cell Lung Cancer (NSCLC)To prospectively look at the utility of routine cervical mediastinoscopy (lymph node biopsy) in patients with clinically staged T2N0M0 NSCLC, as well as patients with clinically…NCT01146366·Atlanta, Georgia and 3 others

TerminatedRadiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung CancerThis randomized phase III trial is studying whole-brain radiation therapy and stereotactic radiosurgery with or without temozolomide or erlotinib to see how well they work…NCT00096265·Scottsdale, Arizona and 82 others

TerminatedCaptopril in Treating Patients With Non-Small Cell Lung Cancer or Limited-Stage Small Cell Lung Cancer That Has Been Previously Treated With Radiation Therapy With or Without ChemotherapyRATIONALE: Captopril is a drug that may be able to decrease side effects caused by radiation therapy, and may improve the quality of life of patients with non-small cell lung…NCT00077064·Birmingham, Alabama and 86 others

RecruitingLung-MAP: A Master Screening Protocol for Previously-Treated Non-Small Cell Lung CancerThis screening and multi-sub-study randomized phase II/III trial will establish a method for genomic screening of similar large cancer populations followed by assigning and…NCT03851445·Birmingham, Alabama and 1228 others

Active not recruitingA Study of Lazertinib With Subcutaneous Amivantamab Compared With Intravenous Amivantamab in Participants With Epidermal Growth Factor Receptor (EGFR)-Mutated Advanced or Metastatic Non-small Cell Lung CancerThe purpose of the study is to simplify amivantamab intravenous administration and to reduce dose times, by assessing a new formulation of amivantamab, amivantamab subcutaneous…NCT05388669·Duarte, California and 186 others

CompletedA Study of Abemaciclib (LY2835219) in Participants With Breast Cancer, Non-small Cell Lung Cancer, or Melanoma That Has Spread to the BrainThe main purpose of this study is to evaluate the safety and effectiveness of the study drug known as abemaciclib in participants with hormone receptor positive breast cancer…NCT02308020·Duarte, California and 43 others

CompletedARCHER 1009 : A Study Of Dacomitinib (PF-00299804) Vs. Erlotinib In The Treatment Of Advanced Non-Small Cell Lung CancerThis is a multinational, multicenter, randomized,double-blinded, Phase 3 study comparing the efficacy and safety of treatment with PF-00299804 to treatment with erlotinib in…NCT01360554·Birmingham, Alabama and 223 others

TerminatedStudy of Talabostat and Pemetrexed vs. Pemetrexed in Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) After Failure of Platinum-Based ChemotherapyThis Phase 3 study will compare the efficacy of talabostat plus pemetrexed to pemetrexed plus placebo in patients with Stage IIIB/IV NSCLC who have failed a platinum-based…NCT00290017·Huntsville, Alabama and 100 others

CompletedSelenium in Preventing Tumor Growth in Patients With Previously Resected Stage I Non-small Cell Lung CancerRATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer.NCT00008385·Mobile, Alabama and 531 others

Active not recruitingProspective Non-Interventional Study Comparing Osimertinib +/- Chemotherapy for EGFR-Mutated NSCLC PatientsThe goal of the study is to collect data on patients treated outside of a clinical trial (in routine clinical practice) with standard of care osimertinib with or without…NCT06538038·Birmingham, Alabama and 145 others

CompletedBevacizumab or Pemetrexed Disodium Alone or In Combination After Induction Therapy in Treating Patients With Advanced Non-Squamous Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy, such as paclitaxel and carboplatin, work in different ways to stop the growth of tumor cells, either by killing the cells or by stopping…NCT01107626·Anniston, Alabama and 433 others

Active not recruitingNivolumab After Surgery and Chemotherapy in Treating Patients With Stage IB-IIIA Non-small Cell Lung Cancer (An ALCHEMIST Treatment Trial)This phase III ALCHEMIST treatment trial studies how well nivolumab after surgery and chemotherapy work in treating patients with stage IB-IIIA non-small cell lung cancer.NCT02595944·Birmingham, Alabama and 883 others

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Other Conditions in North Carolina

Breast Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia Lymphoma