Adrianna Warner

CONTACT

Lead Sponsor

UNC Lineberger Comprehensive Cancer Center

Age

18 - No limit years

Sex

ALL

Healthy Volunteers

No

•Cohort 1A and 1B:
•Participants with metastatic non-small cell lung cancer (NSCLC).
•Written informed consent obtained to participate in the study and HIPAA authorization for release of personal health information.
•Subject is willing and able to comply with study procedures based on the judgement of the investigator.
•Age ≥ 18 years at the time of consent.
•Cohort 2A and 2B:
•Participants with resectable head and neck squamous cell carcinoma (HNSCC)
•Written informed consent obtained to participate in the study and HIPAA authorization for release of personal health information.
•Subject is willing and able to comply with study procedures based on the judgement
•of the investigator.
•Age ≥ 18 years at the time of consent.

•Subject is currently using steroids (prednisone ≥10 mg or its equivalent) and that cannot be discontinued at least 7 days before starting standard of care treatment.
•Prior ICI (PD-1/PD-L1/CTLA4) treatment received less than 6 months from the time of screening.
•Subject is participating in another treatment clinical trial.