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Clareo Health | Lung Cancer Clinical Trials in Massachusetts | 759 Studies

Clinical Trials Lung CancerMassachusetts

Lung Cancer Clinical Trials in Massachusetts

Find 759 clinical trials for lung cancer near Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Massachusetts

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 141-160 of 759 trials

CompletedAn Open-Label Phase 1/2 Study of Itacitinib in Combination With Osimertinib in Subjects With Non-Small Cell Lung CancerThe purpose of this study is to evaluate the safety and tolerability of itacitinib in combination with osimertinib in subjects with locally advanced or metastatic non-small cell…NCT02917993·La Jolla, California and 30 others

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Data from ClinicalTrials.govTerms

CompletedStudying Tumor Tissue Samples From Patients With Early-Stage Non-Small Cell Lung CancerThis research trial studies biomarkers in predicting the risk of cancer returning after surgery in tissue samples of patients with early-stage non-small cell lung cancer.NCT01517971·Boston, Massachusetts

CompletedA Safety and Efficacy Study of Carboplatin, Paclitaxel, Bevacizumab and CA4P in Non-Small Cell Lung CancerThe purpose of this study is to determine the safety, tolerability and efficacy of combretastatin A4 phosphate (CA4P), also known as fosbretabulin, in combination with bevacizumab…NCT00653939·Campbell, California and 14 others

RecruitingSolid Tumor Analysis for HLA Loss of Heterozygosity (LOH) and Apheresis for CAR T- Cell ManufacturingObjective: To collect information on how often a solid tumor cancer might lose the Human Leukocyte Antigen (HLA) by next generation sequencing and perform apheresis to collect…NCT04981119·Gilbert, Arizona and 15 others

Active not recruitingOsimertinib Plus Savolitinib in EGFRm+/MET+ NSCLC Following Prior OsimertinibThis study (the SAVANNAH study) will investigate the efficacy of osimertinib in combination with savolitinib in participants with epidermal growth factor receptor mutation…NCT03778229·La Jolla, California and 89 others

Active not recruitingOsimertinib In EGFR Mutant Lung CancerThis research study is studying a targeted therapy as a possible treatment for Non-Small Cell Lung Cancer (NSCLC) with an EGFR mutation.NCT03586453·Boston, Massachusetts and 1 other

CompletedCPI-006 Alone and in Combination With Ciforadenant and With Pembrolizumab for Patients With Advanced CancersThis is a Phase 1/1b open-label, dose escalation and dose expansion study of CPI-006, a humanized monoclonal antibody (mAb) targeting the CD73 cell-surface ectonucleotidase in…NCT03454451·Tucson, Arizona and 26 others

CompletedZACTIMA (an Anti-EGFR / Anti-VEGF Agent) Combined With Docetaxel Compared to Docetaxel in Non-small Cell Lung CancerThis large phase III clinical study is studying the effect of vandetanib (ZACTIMA) in treating non-small cell lung cancer (NSCLC).NCT00312377·Fullerton, California and 155 others

CompletedPhase 1a/1b Study of TPST-1495 as a Single Agent and in Combination With Pembrolizumab in Subjects With Solid TumorsThis is a first-in-human Phase 1a/1b, multicenter, open-label, dose-escalation, dose and schedule optimization, and expansion study of TPST-1495 as a single agent and in…NCT04344795·Aurora, Colorado and 10 others

CompletedIrofulven in Treating Patients With Relapsed or Refractory Non-small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00003666·Birmingham, Alabama and 47 others

CompletedALTA-1L Study: A Study of Brigatinib Versus Crizotinib in Anaplastic Lymphoma Kinase Positive (ALK+) Advanced Non-small Cell Lung Cancer (NSCLC) ParticipantsThe purpose of the study is to compare the efficacy of brigatinib to that of crizotinib in ALK+ locally advanced or metastatic non-small cell lung cancer (NSCLC) participants…NCT02737501·Sedona, Arizona and 90 others

CompletedComprehensive Genomic Analysis in Tissue and Blood Samples From Young Patients With Lung CancerThis research trial studies genomic analysis in tissue and blood samples from young patients with lung cancer.NCT02273336·Los Angeles, California and 1 other

RecruitingA Study to Investigate the Safety and Efficacy of KQB368 as Monotherapy in Participants With Advanced Solid MalignanciesThe goal of this study is to learn if KQB368 works to treat advanced solid malignancies in adults. The study will also learn about the safety of KQB368.NCT07542704·Los Angeles, California and 13 others

CompletedAn Open-label Study of Encorafenib + Binimetinib in Patients With BRAFV600-mutant Non-small Cell Lung CancerThis is an open-label, multicenter, non-randomized, Phase 2 study to determine the safety, tolerability and efficacy of encorafenib given in combination with binimetinib in…NCT03915951·Yuma, Arizona and 142 others

CompletedStudy Of OX40 Agonist PF-04518600 Alone And In Combination With 4-1BB Agonist PF-05082566To assess the safety and tolerability at increasing dose levels of PF-04518600 alone or in combination wtih PF-05082566 in patients with select advanced or metastatic carcinoma in…NCT02315066·Los Angeles, California and 29 others

CompletedRucaparib in Treating Patients With Genomic LOH High and/or Deleterious BRCA1/2 Mutation Stage IV or Recurrent Non-small Cell Lung Cancer (A Lung-MAP Treatment Trial)This phase II Lung-MAP trial studies how well rucaparib works in treating patients with genomic loss of heterozygosity (LOH) high and/or deleterious BRCA1/2 mutation stage IV…NCT03845296·Mobile, Alabama and 949 others

TerminatedCetuximab as Therapy for Recurrent Non-Small Cell Lung Cancer Patients Who Have Received Prior TherapyThe purpose of this research study is to find out how well cetuximab works in treating NSCLC in patients who have been previously treated with a class of drug called tyrosine…NCT00694603·Boston, Massachusetts and 2 others

RecruitingKEYMAKER-U01 Substudy 01A: Efficacy and Safety Study of Pembrolizumab (MK-3475) With or Without Chemotherapy When Used With Investigational Agents in Treatment-naïve Participants With Stage IV Non-small Cell Lung Cancer (NSCLC) (MK-3475-01A/KEYMAKER-U01A)The purpose of this study is to assess the efficacy and safety of pembrolizumab (MK-3475) with or without chemotherapy in combination with vibostolimab (MK-7684), boserolimab…NCT04165070·Gilbert, Arizona and 46 others

CompletedNon-small Cell Lung Cancer RegistryThis trial will evaluate two separate groups of patients with stage IIIB/IV non-small cell lung cancer.NCT00099541·Birmingham, Alabama and 100 others

RecruitingOsimertinib Alone or With Chemotherapy for EGFR-Mutant Lung CancersThis study will compare the effectiveness of osimertinib alone with the combination of osimertinib and chemotherapy (carboplatin and pemetrexed) in people with metastatic lung…NCT04410796·Sacramento, California and 17 others

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