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Clareo Health | Lung Cancer Clinical Trials in Massachusetts | 759 Studies

Clinical Trials Lung CancerMassachusetts

Lung Cancer Clinical Trials in Massachusetts

Find 759 clinical trials for lung cancer near Massachusetts. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Massachusetts

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4Not applicable

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Showing 121-140 of 759 trials

No longer availableExpanded Treatment Protocol With LDK378 in ALK(+) NSCLCNovartis-sponsored, open-label, multi-center, interventional ETP to provide LDK378 to patients with ALK (+)NSCLC, who have been pre-treated with an ALK inhibitor; except in…NCT01947608·Chandler, Arizona and 49 others

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Data from ClinicalTrials.govTerms

Active not recruitingA Study of Osimertinib With or Without Chemotherapy Versus Chemotherapy Alone as Neoadjuvant Therapy for Patients With EGFRm Positive Resectable Non-Small Cell Lung CancerThis is a Phase III, randomised, controlled, 3-arm, multi-centre study of neoadjuvant osimertinib as monotherapy or in combination with chemotherapy, versus SoC chemotherapy…NCT04351555·Duarte, California and 157 others

CompletedA Phase III Study of the Efficacy of Taxotere/Aptosyn Versus Taxotere/Placebo in Non-Small Cell Lung Cancer PatientsTaxotere has been approved by the FDA and is considered a standard treatment for patients with lung cancer who have failed prior platinum-containing regimens.NCT00085826·Birmingham, Alabama and 113 others

RecruitingPhase III, Open-label, Study of First-line Dato-DXd in Combination With Rilvegostomig for Advanced Non-squamous NSCLC With High PD-L1 Expression (TC ≥ 50%) and Without Actionable Genomic AlterationsThe purpose of this study is to evaluate efficacy and safety of Dato-DXd in combination with rilvegostomig or rilvegostomig monotherapy compared with pembrolizumab monotherapy as…NCT06357533·Anchorage, Alaska and 289 others

CompletedPhase 1/2 Study of Vascular Disrupting Agent NPI-2358 + Docetaxel in Patients With Advanced Non-Small Cell Lung CancerThis is a clinical trial examining the vascular disrupting agent NPI-2358 combined with docetaxel in patients with advanced non-small cell lung cancer (NSCLC).NCT00630110·Scottsdale, Arizona and 35 others

CompletedA Phase II Study to Evaluate the Efficacy and Safety of Oral Ceritinib in Patients With ALK-positive NSCLC Metastatic to the Brain and/or to LeptomeningesThis was a phase II, multi-center, open-label, five-arm study in which the efficacy and safety of oral ceritinib treatment was assessed in patients with NSCLC metastatic to the…NCT02336451·Los Angeles, California and 56 others

TerminatedBiomarkers of Response to Ipilimumab and Nivolumab in First-line NSCLCThis research study is studying two immunotherapy drugs as a possible treatment for advanced non-small cell lung cancer (NSCLC).NCT03425331·Boston, Massachusetts and 2 others

CompletedKEYMAKER-U01 Substudy 2: Efficacy and Safety Study of Pembrolizumab (MK-3475) When Used With Investigational Agents in Treatment-naïve Participants With Anti-programmed Cell Death Receptor Ligand 1 (PD-L1) Positive Advanced Non-small Cell Lung Cancer (NSCLC) (MK-3475-01B/KEYMAKER-U01B)The purpose of this study is to assess the efficacy and safety of pembrolizumab (MK-3475) in combination with MK-4830 in treatment-naïve participants with advanced squamous or…NCT04165083·Gilbert, Arizona and 38 others

RecruitingPhase 1a and Phase 2 Study for Safety, Preliminary Efficacy, PK and PD of ST-067This is a multiphase, multicenter study, which includes a Phase 1a open-label, dose escalation monotherapy study of ST-067 given as an SC injection with or without obinutuzumab…NCT04787042·Scottsdale, Arizona and 5 others

RecruitingA Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 RearrangementsPhase 1 dose escalation will determine the first cycle dose-limiting toxicities (DLTs), the maximum tolerated dose (MTD), the biologically effective dose and recommended Phase 2…NCT03093116·Duarte, California and 164 others

Terminated(HARMONY) Study of BLU-701 in EGFR-mutant NSCLCThis is a Phase 1/2, open-label, first-in-human (FIH) study is designed to evaluate the safety, tolerability, pharmacokinetics, pharmacodynamics, and antitumor activity of BLU-701…NCT05153408·Boston, Massachusetts and 6 others

RecruitingA Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid TumorsThis study will assess the safety and efficacy of VS-7375 alone and in combination in patients with advanced solid tumors harboring a KRAS G12D-mutation.NCT07020221·Los Angeles, California and 21 others

CompletedBevacizumab and Carboplatin/Paclitaxel and Radiation in Non-Small Cell Lung CancerThis study is being done to learn what effects (good and bad) bevacizumab in conjunction with carboplatin/paclitaxel and radiation therapy has on patients with non-small cell lung…NCT00578149·Boston, Massachusetts and 1 other

CompletedVinorelbine in Treating Patients With Stage IIIB or Stage IV Non-Small Cell Lung CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Giving drugs in different ways may kill more tumor cells.NCT00005865·Tucson, Arizona and 49 others

CompletedIntegrated Versus Standard Palliative Care in Patients With Advanced Non-small Cell Lung Cancer (NSCLC)The main purpose of this study is to compare two types of treatment-standard palliative care (which usually is given towards the end of life) and integrated palliative care (which…NCT01038271·Boston, Massachusetts

CompletedStudy of OSI-774 (Tarceva) in Previously Untreated Elderly Lung Cancer PatientsThe primary purpose of this study is to determine whether the drug OSI-774 is less toxic and potentially as good as or better than standard chemotherapy drugs, when given to…NCT00137800·Boston, Massachusetts and 1 other

CompletedAZD9291 First Time In Patients Ascending Dose StudyThis study will treat patients with advanced NSCLC who have already received at least one course of specific anti-cancer treatment but the tumour has started to re-grow following…NCT01802632·Aurora, Colorado and 44 others

CompletedAssess Efficacy and Safety of AZD6244 in Combination With Docetaxel in Patients Receiving Second Line Non Small Cell Lung Cancer Treatment.The purpose of this study is to treat patients with locally advanced or metastatic NSCLC with a combination therapy of selumetinib and two different doses of docetaxel 75mg/m2 or…NCT01750281·Santa Monica, California and 67 others

TerminatedRadiation Therapy and Stereotactic Radiosurgery With or Without Temozolomide or Erlotinib in Treating Patients With Brain Metastases Secondary to Non-Small Cell Lung CancerThis randomized phase III trial is studying whole-brain radiation therapy and stereotactic radiosurgery with or without temozolomide or erlotinib to see how well they work…NCT00096265·Scottsdale, Arizona and 82 others

UnknownTomivosertib Combined With Pembrolizumab in Subjects With PD-L1 Positive NSCLC (KICKSTART)Tomivosertib combined with pembrolizumab in Subjects with PD-L1 positive NSCLCNCT04622007·Daphne, Alabama and 143 others

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