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Clareo Health | Lung Cancer Clinical Trials in Detroit | 433 Studies

Clinical Trials Lung CancerDetroit

Lung Cancer Clinical Trials in Detroit

Find 433 clinical trials for lung cancer near Detroit, Michigan. Connect with research centers in your area.

All Lung Cancer trials nationwide All trials in Detroit

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 81-100 of 433 trials

CompletedEffects of Matuzumab in Combination With Pemetrexed for the Treatment of Advanced Lung CancerThis open-label, multicenter, randomized, controlled, Phase II study is planned to answer questions about how the drug, matuzumab (EMD 72000), works and is part of an effort aimed…NCT00111839·Tucson, Arizona and 57 others

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Data from ClinicalTrials.govTerms

TerminatedA Study Of Avelumab In Combination With Other Cancer Immunotherapies In Advanced Malignancies (JAVELIN Medley)This is a Phase 1b/2 dose-optimization study to evaluate safety, pharmacokinetics, pharmacodynamics, and preliminary antitumor activity of avelumab (MSB0010718C) in combination…NCT02554812·Encinitas, California and 87 others

RecruitingTargeted Treatment for Advanced Non-Small Cell Lung Cancer That Has Increased Copies of the MET Gene (An Expanded Lung-MAP Treatment Trial)This phase II Expanded Lung-MAP treatment trial tests how well amivantamab-subcutaneous (SC) works in treating patients patients with MET amplification non-small cell lung cancer.NCT06116682·Jonesboro, Arkansas and 247 others

RecruitingTesting the Addition of High Dose, Targeted Radiation to the Usual Treatment for Locally-Advanced Inoperable Non-Small Cell Lung CancerThis phase III trial compares the effect of adding stereotactic body radiation therapy (SBRT) to the usual treatment (conventional image guided radiation therapy \[IGRT\] and…NCT05624996·Birmingham, Alabama and 476 others

RecruitingFirst-in-Human Study of ATX-295, an Oral Inhibitor of KIF18A, as Monotherapy and in Combination With Anticancer Therapy in Patients With Advanced or Metastatic Solid Tumors, Including Ovarian CancerThe goal of this study is to identify a safe and tolerated dose of the orally administered KIF18A inhibitor ATX-295.NCT06799065·Aurora, Colorado and 10 others

RecruitingStudy of INBRX-106 and INBRX-106 in Combination With Pembrolizumab (Keytruda®) in Subjects With Locally Advanced or Metastatic Solid Tumors (Hexavalent OX40 Agonist)This is a Phase 1/2, open-label, non-randomized, 4-part trial to determine the safety profile and identify the maximum tolerated dose (MTD) and/or recommended Phase 2 dose (RP2D)…NCT04198766·Duarte, California and 41 others

Active not recruitingA Global Study to Assess the Effects of Durvalumab + Domvanalimab Following Concurrent Chemoradiation in Participants With Stage III Unresectable NSCLCThis is a Phase III, randomised, double-blind, placebo-controlled, multicentre, international study assessing the efficacy and safety of durvalumab (MEDI4736) and domvanalimab…NCT05211895·Chandler, Arizona and 225 others

CompletedA Study of Neoadjuvant Atezolizumab Plus Chemotherapy Versus Placebo Plus Chemotherapy in Patients With Resectable Stage II, IIIA, or Select IIIB Non-Small Cell Lung Cancer (IMpower030)This is a randomized, double-blinded study designed to evaluate the efficacy, safety, pharmacokinetics, and immunogenicity of neoadjuvant treatment with atezolizumab (MPDL3280A)…NCT03456063·Tucson, Arizona and 121 others

CompletedA Study of Atezolizumab Compared With Docetaxel in Participants With Locally Advanced or Metastatic Non-Small Cell Lung Cancer Who Have Failed Platinum-Containing TherapyThis global, multicenter, open-label, randomized, controlled study evaluated the efficacy and safety of atezolizumab (an anti-programmed death-ligand 1 \[anti-PD-L1\]…NCT02008227·Bakersfield, California and 207 others

CompletedS0709: Erlotinib With or Without Carboplatin and Paclitaxel in Stage IIIB or Stage IV Non-Small Cell Lung CancerRATIONALE: Erlotinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.NCT00661193·Little Rock, Arkansas and 123 others

TerminatedPemetrexed Disodium or Erlotinib Hydrochloride as Second-Line Therapy in Treating Patients With Advanced Non-small Cell Lung CancerThis randomized phase III trial studies pemetrexed disodium to see how well it works compared with erlotinib hydrochloride as second-line therapy in treating patients with…NCT00738881·Scottsdale, Arizona and 268 others

TerminatedStudy of BMS-275183 in Patients With Pre-treated Non-small Cell Lung CancerThe purpose of this clinical research study is to learn if BMS-275183 can shrink or slow the growth of the cancer in subjects with non-small cell lung cancer (NSCLC).NCT00099879·Sacramento, California and 19 others

TerminatedA Study of NM21-1480 in Adult Patients With Advanced Solid TumorsThis is a first-in-human, open-label, multi-center, Phase 1/2, dose-escalation study with expansion cohorts to evaluate NM21-1480 for safety and immunogenicity, to determine the…NCT04442126·Fort Collins, Colorado and 25 others

CompletedErlotinib (Tarceva) as a Single Agent or Intercalated With Combination Chemotherapy in Patients With EGFR Positive NSCLCThis will be the first prospective study where patients will be selected on the basis of two measures of the epidermal growth factor receptor (EGFR) pathway.NCT00294762·Alhambra, California and 42 others

TerminatedDS-8201a in Human Epidermal Growth Factor Receptor 2 (HER2)-Expressing or -Mutated Non-Small Cell Lung CancerThe primary objective of this trial is to evaluate the efficacy of trastuzumab deruxtecan in HER2-overexpressing and/or HER2-mutated advanced NSCLC participants.NCT03505710·La Jolla, California and 20 others

TerminatedTusamitamab Ravtansine (SAR408701) in Combination With Ramucirumab or Ramucirumab and Pembrolizumab in Pretreated Patients With NSQ NSCLC (CARMEN-LC04)Primary Objectives: Doublet Cohort Part 1 (safety run-in): To assess the tolerability and to confirm the recommended dose of tusamitamab ravtansine in combination with…NCT04394624·Detroit, Michigan and 12 others

CompletedA Study of Pembrolizumab (MK-3475) With or Without Maintenance Olaparib in First-line Metastatic Squamous Non-small Cell Lung Cancer (NSCLC, MK-7339-008/KEYLYNK-008)The current study will compare pembrolizumab (MK-3475) plus maintenance olaparib, vs. pembrolizumab plus maintenance olaparib placebo for the treatment of squamous NSCLC.NCT03976362·Birmingham, Alabama and 177 others

CompletedStudy of XL647 in Subjects With Non-Small-Cell Lung CancerThe purpose of this phase II study is to determine the safety, tolerability, and activity of XL647 in previously untreated subjects with non-small cell lung cancer (NSCLC).NCT00364780·Port Saint Lucie, Florida and 6 others

CompletedStudy of XL281 in Adults With Solid TumorsThe purpose of this study is to determine the safest dose of the multiple Raf kinase inhibitor (including c-Raf, B-Raf, and the activated mutant B-RafV600E) XL281, how often it…NCT00451880·Scottsdale, Arizona and 5 others

UnknownA Dose Escalation With Expansion Study of EMB-01 in Participants With Advanced/Metastatic Solid TumorsFirst-in-human, Phase I/II, Multicenter, Open-Label Study of EMB-01 in Patients with Advanced/Metastatic Solid TumorsNCT03797391·Boston, Massachusetts and 4 others

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