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Lung Screening Study | Clinical Trials | Clareo Health

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COMPLETEDNANCT00006382

Lung Screening Study

RATIONALE: New imaging procedures such as spiral CT may improve the ability to detect lung cancer in patients who are at high risk for the disease. PURPOSE: Randomized clinical trial to compare the e...

Lead sponsor: National Cancer Institute (NCI)•6 U.S. locations•View source on ClinicalTrials.gov

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Sponsors

Lead Sponsor

National Cancer Institute (NCI)

OBJECTIVES: I. Compare the efficacy of screening spiral CT scan and screening chest x-ray in detecting lung cancer in current or former smokers at high risk for lung cancer. OUTLINE: This is a randomized, multicenter study of lung cancer screening. Patients are randomized to one of two screening arms. Arm I: Patients undergo one spiral CT scan. Arm II: Patients undergo one chest x-ray. Patients and their primary care physicians are notified of test results within 3 weeks of the exam. PROJECTED ACCRUAL: A total of 3,000 participants (1,500 per screening arm) will be accrued for this study at six screening centers (500 per center) by October 31, 2000.

Age

55 - 74 years

Sex

ALL

Healthy Volunteers

No

Inclusion Criteria

•DISEASE CHARACTERISTICS: See General Eligibility Criteria
•PATIENT CHARACTERISTICS: Age: 55 to 74 Patients with a cigarette smoking history of at least 30 pack-years Current smoker OR Smoker who has quit smoking within the past 10 years No known prior history of lung cancer
•PRIOR CONCURRENT THERAPY: No concurrent therapy for any cancer except nonmelanomatous skin cancer No prior removal of any portion of the lungs No concurrent participation in other cancer screening trial, including PLCO No concurrent participation in a primary cancer prevention trial other than a smoking cessation trial

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Data from ClinicalTrials.govLast updated on ClinicalTrials.gov: May 5, 2015Terms

Trial snapshot

StatusCOMPLETED

PhaseNA

Enrollment—

Start dateAug 2000

Last updatedMay 5, 2015

Condition

Locations shown

University of Alabama Comprehensive Cancer Center

Birmingham, Alabama

Vincent T. Lombardi Cancer Research Center, Georgetown University

Washington D.C., District of Columbia

Henry Ford Hospital

Detroit, Michigan

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Data Source & Attribution

This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.

ClinicalTrials.gov last update: May 5, 2015Data synced to Clareo: May 17, 2026

Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.

Neither the United States Government nor Clareo Health make any warranties regarding the data. Check ClinicalTrials.gov frequently for updates.

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