Liver Disease Clinical Trials in Philadelphia

Showing 21-36 of 36 trials

Sofosbuvir Based DAA Therapy in HIV/HCV Coinfected Pre or Post Liver Transplant

NCT02533934

Retrospective/Prospective, open-label study using sofosbuvir based DAA therapy to treat HIV/HCV coinfected pre or post liver transplant participants

HIVHepatitis CCirrhosis

University of California, San Francisco68 participantsStarted Aug 2016

San Francisco, California, United States • Washington D.C., District of Columbia, United States • Baltimore, Maryland, United States +5 more locations

COMPLETED< 1 mile

The Patient-Reported Outcomes Project of HCV-TARGET

NCT02601820

The PROP UP research study is funded by The Patient Centered Outcomes Research Institute (PCORI). PROP UP is a multi-centered prospective observational study that will evaluate all-oral treatment regimens for chronic hepatitis C viral (HCV) infection regarding several patient-reported outcomes (PROs) such as HCV-associated symptoms, treatment side effects, medication adherence, out of pocket costs, comorbid conditions, and long-term benefits of cure and harms of treatment to compare PROs of different treatment regimens, treatment durations, and patient subgroups. Participants will be recruited from 9 U.S. liver centers. Approximately 1920 patients with HCV infection who are prescribed a regimen containing Sofosbuvir/Ledipasvir(SOF/LED), SOF/Velpatasvir(SOF/VEL), Grazoprevir/Elbasvir(GRZ/ELB), OBV/PTV/r + DSV (PRoD), or daclatasvir/SOF (DAC/SOF) will be recruited and approximately 1600 patients who are approved and begin HCV treatment will be enrolled in the longitudinal study. PRO surveys will be evaluated before, during and after HCV treatment. PROP UP is a collaborative effort between behavioral and biomedical researchers, a patient engagement group and a patient advocacy organization.

Hepatitis C, ChronicLiver Diseases

University of North Carolina, Chapel Hill1,601 participantsStarted Nov 2015

Davis, California, United States • New Haven, Connecticut, United States • Gainesville, Florida, United States +8 more locations

Sofosbuvir Based DAA Therapy in HIV/HCV Coinfected Pre or Post Liver Transplant

The Patient-Reported Outcomes Project of HCV-TARGET

Liver Disease Trials in Other Cities

The Safety/Efficacy of Rifaximin With/Without Lactulose in Participants With A History of Recurrent Hepatic Encephalopathy

Mycophenolate Mofetil Immunosuppression Without/With Reduced Dose Calcineurin Inhibitor Long After Liver Transplantation

A Study of OCE-205 in Participants With Cirrhosis With Ascites Who Developed Hepatorenal Syndrome-Acute Kidney Injury

Study to Evaluate the Efficacy and Safety of CC-90001 in Participants With Non-alcoholic Steatohepatitis (NASH) and Liver Fibrosis

Cysteamine Bitartrate Delayed-Release for the Treatment of NAFLD in Children

An Open-label Study to Evaluate the Long-term Safety and Tolerability of LUM001 in Patients With Primary Biliary Cirrhosis

Oral Hepatitis C Treatment for Indolent Lymphoma (OPTImaL) Study

A2ALL-Patients Safety System Improvements in Living Donor Liver Transplantation

Rollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic Steatohepatitis

Pharmacokinetic and Pharmacodynamic Study of IDN-6556 in ACLF

Tesamorelin Effects on Liver Fat and Histology in HIV

Assessing Portal Hypertension With Methacetin Breath Test

Non-invasive Methods and Surgical Risk Stratification in Cirrhotics Undergoing Elective Extrahepatic Surgery

Pharmacokinetics and Safety of Single Subcutaneous Pasireotide (SOM230) in Subjects With Varying Degrees of Hepatic Function

Other Conditions in Philadelphia