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Clareo Health | Liver Disease Clinical Trials in Houston | 25 Studies

Clinical Trials Liver DiseaseHouston

Liver Disease Clinical Trials in Houston

Find 25 clinical trials for liver disease near Houston, Texas. Connect with research centers in your area.

All Liver Disease trials nationwide All trials in Houston

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 1-20 of 25 trials

CompletedStudy Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Nonalcoholic SteatohepatitisThe primary objective of this study is to evaluate whether obeticholic acid (OCA; INT-747) can lead to histological improvement in fibrosis with no worsening of NASH in adults…NCT03439254·Dothan, Alabama and 191 others

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Data from ClinicalTrials.govTerms

RecruitingA Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASHThis is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis due to NASH/MASH.NCT06528314·Birmingham, Alabama and 330 others

Active not recruitingA Phase 3 Study to Evaluate the Efficacy and Safety of MGL-3196 (Resmetirom) in Patients With NASH and FibrosisA double-blind placebo controlled randomized Phase 3 study to determine if 80 or 100 mg of MGL-3196 as compared with placebo resolves NASH and/or reduces fibrosis on liver biopsy…NCT03900429·Birmingham, Alabama and 246 others

CompletedA Study of Efruxifermin in Subjects With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH) (Symmetry)This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in cirrhotic subjects with biopsy-proven F4 compensated NASH.NCT05039450·Chandler, Arizona and 48 others

TerminatedSimtuzumab (SIM, GS-6624) in the Treatment of Cirrhosis Due to NASHThe primary objective of this study is to evaluate the safety and efficacy of SIM (formerly referred to as GS-6624) in adults with compensated cirrhosis due to Non-Alcoholic…NCT01672879·Phoenix, Arizona and 58 others

RecruitingA Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASHThe study will assess the efficacy and safety of pegozafermin administered in participants with compensated cirrhosis due to MASH (biopsy-confirmed fibrosis stage F4 MASH…NCT06419374·Birmingham, Alabama and 325 others

CompletedStudy of Semaglutide, and Cilofexor/Firsocostat, Alone and in Combination, in Adults With Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)The goal of this clinical study is to understand whether the study drugs, semaglutide (SEMA) with the fixed-dose combination (FDC) of cilofexor/firsocostat (CILO/FIR), cause…NCT04971785·Birmingham, Alabama and 241 others

TerminatedStudy to Evaluate the Efficacy and Safety of CC-90001 in Participants With Non-alcoholic Steatohepatitis (NASH) and Liver FibrosisThis is a Phase 2, randomized, double-blind, placebo-controlled, multicenter, multinational, dose-finding study evaluating the efficacy of three treatment doses of CC-90001…NCT04048876·Phoenix, Arizona and 141 others

CompletedA Phase 3 Study to Evaluate Safety and Biomarkers of Resmetirom (MGL-3196) in Non Alcoholic Fatty Liver Disease PatientsA double-blind placebo controlled randomized Phase 3 study to evaluate the safety and tolerability of once-daily, oral administration of 80 or 100 mg resmetirom versus matching…NCT04197479·Birmingham, Alabama and 76 others

CompletedA Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Liver CirrhosisThis is a study of experimental medication BMS-986036 given to adults with Nonalcoholic Steatohepatitis (NASH; the buildup of fat and inflammation in the liver that is not caused…NCT03486912·Madison, Alabama and 90 others

CompletedStudy to Evaluate the Safety and Efficacy of Selonsertib, Firsocostat, Cilofexor, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)The primary objectives of this study are: * To assess the safety and tolerability of selonsertib (SEL), firsocostat (FIR) and cilofexor (CILO), administered alone or in…NCT03449446·Chandler, Arizona and 100 others

CompletedA Study to Evaluate AZD2693 in Participants Who Are Carriers of the PNPLA3 148M Risk Allele With Non-cirrhotic Non-alcoholic Steatohepatitis With FibrosisA Study to Evaluate the Efficacy, Safety and Tolerability of AZD2693 given by subcutaneous injection in adult participants with non-cirrhotic non-alcoholic steatohepatitis with…NCT05809934·Chandler, Arizona and 163 others

TerminatedRollover Study of Cenicriviroc for the Treatment of Liver Fibrosis in Participants With Nonalcoholic SteatohepatitisThis rollover study will provide open-label treatment with cenicriviroc and will assess the long-term safety of continued treatment with cenicriviroc in participants who…NCT03059446·Dothan, Alabama and 70 others

CompletedStudy of Aldafermin (NGM282) in Subjects With Compensated Cirrhosis (ALPINE 4)A multi-center evaluation of aldafermin in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis.NCT04210245·Glendale, Arizona and 48 others

TerminatedSafety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH)The purpose of this randomized study is to assess safety and effectiveness of BMS-986263 in adults with compensated cirrhosis (chronic liver disease) from nonalcoholic…NCT04267393·Chandler, Arizona and 111 others

TerminatedMild Hypothermia and Acute Kidney Injury in Liver TransplantationAcute kidney injury (AKI), or worsening kidney function, is a common complication after liver transplantation (20-90% in published studies).NCT03534141·San Francisco, California and 2 others

TerminatedSafety and Efficacy of Simtuzumab (SIM, GS-6624) in Adults With Advanced Liver Fibrosis But Not Cirrhosis Secondary to Non-Alcoholic Steatohepatitis (NASH)The primary objective of this study is to evaluate whether SIM (formerly referred to as GS-6624) is effective at preventing the histologic progression of liver fibrosis and the…NCT01672866·Phoenix, Arizona and 67 others

CompletedEmricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal HypertensionThis is a multicenter, randomized, double-blind, placebo-controlled trial involving subjects with NASH cirrhosis and severe portal hypertension (defined as HVPG ≥12 mmHg as…NCT02960204·Pasadena, California and 36 others

RecruitingA Study of Efimosfermin Alfa in Participants With Biopsy-confirmed Cirrhosis (Compensated) Due to MASHThe purpose of this study is to evaluate the safety, tolerability, preliminary efficacy, and pharmacokinetics (PK) of efimosfermin in participants with metabolic dysfunction…NCT06920043·Chandler, Arizona and 29 others

CompletedClinical Performance of LIVERFASt Test Compared w/ Liver Biopsy in Patients w/ NAFLD.The primary objective of this study is to assess the clinical performance of LIVERFAStTM In Vitro Diagnostic (IVD) Tests (Fibrosis score, Activity score and Steatosis score) in…NCT04579874·Detroit, Michigan and 7 others

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