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Clareo Health | Liver Disease Clinical Trials in Philadelphia | 14 Studies

Clinical Trials Liver DiseasePhiladelphia

Liver Disease Clinical Trials in Philadelphia

Find 14 clinical trials for liver disease near Philadelphia, Pennsylvania. Connect with research centers in your area.

All Liver Disease trials nationwide All trials in Philadelphia

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

Who can join

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Showing 1-14 of 14 trials

CompletedStudy Evaluating the Efficacy and Safety of Obeticholic Acid in Subjects With Compensated Cirrhosis Due to Nonalcoholic SteatohepatitisThe primary objective of this study is to evaluate whether obeticholic acid (OCA; INT-747) can lead to histological improvement in fibrosis with no worsening of NASH in adults…NCT03439254·Dothan, Alabama and 191 others

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Data from ClinicalTrials.govTerms

RecruitingA Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASHThis is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with compensated cirrhosis due to NASH/MASH.NCT06528314·Birmingham, Alabama and 330 others

TerminatedSimtuzumab (SIM, GS-6624) in the Treatment of Cirrhosis Due to NASHThe primary objective of this study is to evaluate the safety and efficacy of SIM (formerly referred to as GS-6624) in adults with compensated cirrhosis due to Non-Alcoholic…NCT01672879·Phoenix, Arizona and 58 others

CompletedThe Visceral Adiposity Measurement and Observation StudyThe Visceral Adiposity Measurement and Observation StudyNCT05383456·Los Angeles, California and 7 others

RecruitingA Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASHThe study will assess the efficacy and safety of pegozafermin administered in participants with compensated cirrhosis due to MASH (biopsy-confirmed fibrosis stage F4 MASH…NCT06419374·Birmingham, Alabama and 325 others

CompletedA Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Liver CirrhosisThis is a study of experimental medication BMS-986036 given to adults with Nonalcoholic Steatohepatitis (NASH; the buildup of fat and inflammation in the liver that is not caused…NCT03486912·Madison, Alabama and 90 others

CompletedStudy to Evaluate the Safety and Efficacy of Selonsertib, Firsocostat, Cilofexor, and Combinations in Participants With Bridging Fibrosis or Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)The primary objectives of this study are: * To assess the safety and tolerability of selonsertib (SEL), firsocostat (FIR) and cilofexor (CILO), administered alone or in…NCT03449446·Chandler, Arizona and 100 others

TerminatedSafety and Effectiveness of BMS-986263 in Adults With Compensated Cirrhosis (Liver Disease) From Nonalcoholic Steatohepatitis (NASH)The purpose of this randomized study is to assess safety and effectiveness of BMS-986263 in adults with compensated cirrhosis (chronic liver disease) from nonalcoholic…NCT04267393·Chandler, Arizona and 111 others

TerminatedSafety and Efficacy of Simtuzumab (SIM, GS-6624) in Adults With Advanced Liver Fibrosis But Not Cirrhosis Secondary to Non-Alcoholic Steatohepatitis (NASH)The primary objective of this study is to evaluate whether SIM (formerly referred to as GS-6624) is effective at preventing the histologic progression of liver fibrosis and the…NCT01672866·Phoenix, Arizona and 67 others

CompletedEmricasan, an Oral Caspase Inhibitor, in Subjects With NASH Cirrhosis and Severe Portal HypertensionThis is a multicenter, randomized, double-blind, placebo-controlled trial involving subjects with NASH cirrhosis and severe portal hypertension (defined as HVPG ≥12 mmHg as…NCT02960204·Pasadena, California and 36 others

TerminatedSafety and Efficacy of Selonsertib in Adults With Compensated Cirrhosis Due to Nonalcoholic Steatohepatitis (NASH)The primary objective of this study is to evaluate whether selonsertib (SEL; GS-4997) can cause fibrosis regression and reduce associated complications in adults with cirrhosis…NCT03053063·Chandler, Arizona and 282 others

CompletedA Study of Experimental Medication BMS-986036 in Adults With Nonalcoholic Steatohepatitis (NASH) and Stage 3 Liver FibrosisThis is a study of experimental medication BMS-986036 given to adults with Nonalcoholic Steatohepatitis (NASH; the buildup of fat and inflammation in the liver that is not caused…NCT03486899·Madison, Alabama and 88 others

TerminatedStudy Evaluating the Efficacy and Safety of Belapectin for the Prevention of Esophageal Varices in NASH CirrhosisThis seamless, adaptive, two-stage, Phase 2b/3, randomized, double-blind, multicenter, parallel-groups, placebo-controlled study will assess the efficacy, safety, and tolerability…NCT04365868·Birmingham, Alabama and 155 others

UnknownEmricasan, a Caspase Inhibitor, for Treatment of Subjects With Decompensated NASH CirrhosisThis is a multicenter, double-blind, randomized, placebo-controlled study to evaluate the safety and efficacy of emricasan in improving event-free survival based on a composite…NCT03205345·Chandler, Arizona and 75 others

Other Conditions in Philadelphia

Breast Cancer Lung Cancer Prostate Cancer Colorectal Cancer Melanoma Leukemia