Leukemia Clinical Trials in Pittsburgh

Showing 881-900 of 1,534 trials

Screening for Colonization With Resistant Enterobacterales in Neutropenic Patients With Hematologic Malignancies

NCT04710212

This is a prospective, observational cohort study to assess the frequency with which neutropenic patients with hematologic malignancies and hematopoietic cell transplant (HCT) recipients are colonized with fluoroquinolone-resistant Enterobacterales (FQRE) and the clinical impact of FQRE colonization.

Hematologic MalignancyLeukemia, AcuteNeutropenia+1 more

Duke University168 participantsStarted Mar 2021

San Francisco, California, United States • Nutley, New Jersey, United States • New York, New York, United States +3 more locations

RECRUITINGPhase 1/2< 1 mile

KRT-232 and TKI Study in Chronic Myeloid Leukemia

NCT04835584

This study evaluates KRT-232, a novel oral small molecule inhibitor of MDM2, for the treatment of patients with Ph+ Chronic Myeloid Leukemia (CML) who have relapsed or are refractory or intolerant to a Tyrosine Kinase Inhibitor (TKI). This study is a global, open label Phase 1b/2 to determine the efficacy and safety of KRT-232 in patients with chronic phase CML (CML-CP) and accelerated phase (CML-AP) who have failed TKI treatments.

Chronic Myeloid Leukemia

Kartos Therapeutics, Inc.109 participantsStarted May 2021

Birmingham, Alabama, United States • Augusta, Georgia, United States • Pittsburgh, Pennsylvania, United States +23 more locations

Screening for Colonization With Resistant Enterobacterales in Neutropenic Patients With Hematologic Malignancies

KRT-232 and TKI Study in Chronic Myeloid Leukemia

Leukemia Trials in Other Cities

Ublituximab in Combination With Ibrutinib Versus Ibrutinib Alone in Participants With Previously Treated High-Risk Chronic Lymphocytic Leukemia (CLL)

Multi-dose Pharmacokinetics and Dose Ranging of Inositol in Premature Infants (INS-2)

A Study to Assess the Impact of Omalizumab on Exercise Capacity, Physical Activity, and Sleep Quality in Participants With Moderate to Severe Allergic Asthma

An Efficacy and Safety Study Of Pracinostat In Combination With Azacitidine In Adults With Acute Myeloid Leukemia

Avelumab in First-Line Maintenance Gastric Cancer (JAVELIN Gastric 100)

Donor Bone Marrow Transplant With or Without G-CSF in Treating Young Patients With Hematologic Cancer or Other Diseases

Sorafenib/Erlotinib Versus Erlotinib Alone in Previously Treated Advanced Non-Small-Cell Lung Cancer (NSCLC)

CMF Bone Stimulation as Adjunct to Surgical Treatment of Ankle Fractures

Study to Evaluate Dupilumab Monotherapy in Pediatric Patients With Peanut Allergy

Study of an Immunotherapeutic, DPX-Survivac, in Combination With Low Dose Cyclophosphamide & Pembrolizumab, in Subjects With Selected Advanced & Recurrent Solid Tumors

PDR001 Plus LAG525 for Patients With Advanced Solid and Hematologic Malignancies

Oral Immunotherapy for Desensitization in Children, Adolescents, and Young Adults With Hen Egg Allergy

Safety and Efficacy of ATIR101 as Adjunctive Treatment to Blood Stem Cell Transplantation From a Haploidentical Family Donor Compared to Post-transplant Cyclophosphamide in Patients With Blood Cancer

Collect and Assess Tissue Samples From Subjects With Hematologic Malignancy

A Study of LY3023414 in Participants With Advanced Cancer

Safety and Efficacy of Isatuximab in Lymphoblastic Leukemia

Trial of AB-110 in Adults With Hematologic Malignancies Undergoing Cord Blood Transplantation

PSB202 in Patients With Previously Treated-, Relapsed-, Indolent B-Cell Malignancies

Other Conditions in Pittsburgh