Hypertension Clinical Trials

Showing 521-540 of 3,518 trials

Influence of Periodontal Diseases on Vascular Parameters in Patients Suffering of Hypertension

NCT02394860

The aim of this study is to assess the influence of the severity of chronic periodontitis on hemodynamic parameters in hypertensive patients.Secondary purposes of this protocol is to identify evolution of several biomarkers and correlate the clinical situation with oral microflora.

Chronic PeriodontitisHypertension

University Hospital, Strasbourg, France76 participantsStarted Apr 2015

Strasbourg, France

TERMINATEDPhase 4

Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1

NCT03738878

The purpose of this study is to test the hypothesis that combined angiotensin receptor blockade (ARB)/neprilysin (NEP) inhibition potentiates the effects of exogenous bradykinin, substance P, and brain natriuretic peptide (BNP) on forearm blood flow or endothelial tissue-type plasminogen activator (t-PA) release compared to ARB alone. A secondary goal is to determine if there is an interactive effect of ARB/NEP inhibition and dipeptidyl peptidase 4 (DPP4) inhibition on responses to these peptides.

Hypertension

Vanderbilt University Medical Center4 participantsStarted Nov 2018

Nashville, Tennessee, United States

RECRUITINGNA

Sleep Restriction and Parental History of Hypertension

NCT06482814

The purpose of this study is to research the effects of partial sleep deprivation (sleep restriction) in a group of individuals whose parents have high blood pressure compared to a group of individuals whose parents have normal blood pressure.

Hypertension

Mayo Clinic44 participantsStarted Feb 2025

Rochester, Minnesota, United States

Influence of Periodontal Diseases on Vascular Parameters in Patients Suffering of Hypertension

Mechanism(s) Underlying Hypotensive Response to ARB/NEP Inhibition - Aim 1

Sleep Restriction and Parental History of Hypertension

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