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Optic Nerve Sheath Measurement and Angiogenic Factors for the Diagnosis of Pre-eclampsia
Hypertensive disorders of pregnancy (HPT) are an important cause of maternal-feto-neonatal morbidity and mortality, being one of the three leading causes of maternal death in our country and in developing countries. The only cure for THE is termination of pregnancy, which ends up being a decision in which gestational age and maternal risks must be balanced. Angiogenic factors have come to occupy an indispensable place in the arsenal of tools that can be used to separate the patient with a high likelihood of complications from those in whom prolongation of pregnancy could represent an important neonatal benefit. Refining the diagnostic capability of this test would further improve maternal-fetal outcomes and the use of optic nerve sheath diameter (ONSD) measurement could make the difference. The purpose of the present study is to correlate the measurement of ONSD with serum angiogenic factor (AF) values in patients with pre-eclampsia and to determine its predictive ability for adverse perinatal outcomes.
Age
18 - No limit years
Sex
FEMALE
Healthy Volunteers
Yes
Saint Thomas Hospital
Panama City, Provincia de Panamá, Panama
Start Date
August 15, 2025
Primary Completion Date
December 31, 2025
Completion Date
January 30, 2026
Last Updated
August 26, 2025
200
ESTIMATED participants
ONSD+AF
PROCEDURE
Lead Sponsor
Saint Thomas Hospital, Panama
NCT06408181
NCT06821685
Data Source & Attribution
This clinical trial information is sourced from ClinicalTrials.gov, a service of the U.S. National Institutes of Health.
Modifications: This data has been reformatted for display purposes. Eligibility criteria have been parsed into inclusion/exclusion sections. Location data has been geocoded to enable distance-based search. For the authoritative and most current information, please visit ClinicalTrials.gov.
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View ClinicalTrials.gov Terms and ConditionsNCT04520048