Heart Disease Clinical Trials in Philadelphia

Showing 41-60 of 263 trials

Gamification to Increase Mobility in the Hospital

NCT04300764

Low mobility is a mediator for poor outcomes of hospital care. Wearable devices will be used and 2-way texting via patient smartphones to monitor patients' physical activity during hospitalization with and without gamification to improve patient adherence to existing guidance on recommended activity. After discharge, investigators will assess patient care utilization (SNF, inpatient vs home rehab, ED visits, readmission) and conduct validated surveys on patient function at 30 days after discharge.

Coronary Artery DiseaseCoronary Heart DiseaseHypertension+4 more

University of PennsylvaniaStarted Jan 2026

Philadelphia, Pennsylvania, United States

RECRUITINGPHASE3< 1 mile

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

NCT06898515

The objective of this study is to prospectively compare decongestive therapy administered by the Reprieve System to Optimal Diuretic Therapy (ODT) in the treatment of patients diagnosed with acute decompensated heart failure (ADHF). The main objective is to determine if the Reprieve System can more efficiently decongest ADHF patients in comparison to Control Therapy.

Acute Decompensated Heart Failure

Reprieve Cardiovascular, Inc400 participantsStarted Jul 2025

Irvine, California, United States • La Jolla, California, United States • Sacramento, California, United States +50 more locations

Gamification to Increase Mobility in the Hospital

Fluid Management of Acute Decompensated Heart Failure Subjects Treated With Reprieve System (FASTR-II) (IDE-G210258)

Heart Disease Trials in Other Cities

Research Study to Look at How Well Semaglutide Works in People Living With Heart Failure, Obesity and Type 2 Diabetes

Innovative Support for Patients With SARS-COV2 Infections (COVID-19) Registry (INSPIRE)

The EMPOWER Trial - The Carillon Mitral Contour System® in Treating Heart Failure With at Least Mild FMR

RCT of Strategies to Augment Physical Activity in Black and Hispanic Breast and Prostate Cancer Survivors (ALLSTAR)

ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation

SyncAV Post-Market Trial

A Study of Tirzepatide (LY3298176) in Participants With Heart Failure With Preserved Ejection Fraction (HFpEF) and Obesity: The SUMMIT Trial

Propensity-Matched Study of Cardiac Contractility Modulation Therapy in Heart Failure

A Study of Vericiguat (MK-1242) in Participants With Chronic Heart Failure With Reduced Ejection Fraction (HFrEF) (MK-1242-035)

Personalized Therapy Study - HFRS (TriageHF) Post Approval Study

EVOLVE-MI: EVOLocumab Very Early After Myocardial Infarction

Ferric Citrate for the Prevention of Renal Failure in Adults With Advanced Chronic Kidney Disease

Study of JK07 in Patients With Chronic Heart Failure

Comparative Effectiveness of Carvedilol Versus Metoprolol Succinate in Heart Failure Patients With an Implantable Cardioverter Defibrillator

STICH3C Cardiac Magnetic Resonance Observational Study

SELUTION 4 De Novo Small Vessel IDE Trial

A Study of AZD3427 in Participants With Heart Failure and Pulmonary Hypertension Group 2

The PLATFORM Study: Prospective LongitudinAl Trial of FFRct: Outcome and Resource IMpacts)

Other Conditions in Philadelphia