Diabetes Clinical Trials in Massachusetts

Showing 281-300 of 301 trials

Third Optimizing Anti-Platelet Therapy in Diabetes MellitUS (OPTIMUS-3)

NCT00642174

This trial is designed as a phase 2 randomized, double-blind double dummy, active comparator controlled, two-period two-arm crossover study to enroll 40 patients across multiple centers. The study will compare platelet function following a prasugrel loading dose and 1 week of prasugrel maintenance therapy with high-dose clopidogrel loading dose and 1 week of high-dose clopidogrel maintenance therapy in patients with drug treated type 2 diabetes mellitus who have coronary artery disease. Various assays of platelet function will be used in this study. Platelet function will be studied using the following assays: Accumetrics VerifyNowTM P2Y12, Light Transmittance Aggregometry (LTA), Vasodilator-associated stimulated phosphoprotein (VASP), and Thromboelastography (TEG)-platelet mapping.

Diabetes MellitusCoronary Artery Disease

Eli Lilly and Company35 participantsStarted Apr 2008

Jacksonville, Florida, United States • Worcester, Massachusetts, United States • New York, New York, United States +1 more locations

COMPLETEDPHASE318 miles

Demonstrate Exubera Works As Well As Avandia When Added To Sulfonylurea + Metformin In Controlling Glucose

NCT00150410

* Whether a combination of three therapies - metformin and a sulfonylurea plus Exubera, an investigational drug, controls your diabetes at least as much as a triple combination therapy of metformin and a sulfonylurea plus Avandia, a Food and Drug Administration (FDA) approved drug. * Whether a combination of two therapies - metformin plus Exubera controls your diabetes at least as much as a as a triple combination therapy of metformin and a sulfonylurea plus Avandia.

Diabetes Mellitus

Pfizer626 participantsStarted Jan 2003

Mesa, Arizona, United States • Phoenix, Arizona, United States • Tucson, Arizona, United States +116 more locations

Third Optimizing Anti-Platelet Therapy in Diabetes MellitUS (OPTIMUS-3)

Demonstrate Exubera Works As Well As Avandia When Added To Sulfonylurea + Metformin In Controlling Glucose

Diabetes Trials in Other Cities

Diabetes Prevention in Women With a Recent History of Gestational Diabetes (Focus Groups)

Pilot Study Of The Effects Of Resveratrol On Endothelial Function In Subjects With Type 2 Diabetes Mellitus

Diabetes Control and Complications Trial (DCCT)

Exubera Large Simple Trial To Evaluate Long-Term Pulmonary And Cardiovascular Safety

Self Monitoring of Blood Glucose With Finger Tip vs. Alternate Site Sampling: Effect on Long Term Glycemic Control

Study Comparing Muraglitazar With Glimepiride in Type 2 Diabetics Who Are Not Controlled With Metformin Alone

Post-PCI:Cardiac Imaging in Patients With Diabetes to Detect Coronary Artery Blockages Previously Opened by Angioplasty

Study Evaluating Rimonabant Efficacy in Insulin-Treated Diabetic Patients(ARPEGGIO)

GALLANT 14 Tesaglitazar vs. Metformin and Fenofibrate

A Study to Evaluate NBI-6024 in Adult and Adolescent Patients With New Onset of Type 1 Diabetes Mellitus

Comparison of Two Basal Insulins for Patients With Type 2 Diabetes (IOOY)

GALLANT 6 Tesaglitazar vs. Pioglitazone

Comparison of Eprosartan/HCT Versus Enalapril/HCT in Hypertensives With Type II Diabetes

Treatment Effect of Saxagliptin Compared With Placebo in Patients With Type 2 Diabetes and Renal Impairment

A Phase 2b Study of DIO-902 or DIO-902 Placebo in Addition to Metformin and Atorvastatin or Atorvastatin Placebo for Type 2 Diabetes

Open Label Safety & Pharmacodynamic Study 24Wk w/DIO-902 Combo w/Metformin & Atorvastatin in T2DM Patients

DPBRN Blood Sugar Testing in Dental Patients

Mechanism of Action and Efficacy of Muraglitazar in Type 2 Diabetes

Other Conditions in Massachusetts