Diabetes Clinical Trials in Boston

Showing 161-180 of 300 trials

Dose-Dependent Effects of Erythritol on Endothelial Function in Type 2 Diabetes Mellitus

NCT01908348

This study is an open-label pilot designed to examine the dose-dependent effects of erythritol, a zero calorie sweetener, on endothelial function. Twenty-four subjects with type 2 diabetes mellitus will make three study visits. At each visit, the will consume an orange-flavored beverage containing escalating amounts of erythritol (6, 12, and 18 grams). Endothelial function will be assessed before and two hours after beverage consumption. Endothelial function will be measured as the change in pulse amplitude in response to reactive hyperemia measured in the fingertip by peripheral arterial tonometry. The results will be used to plan a randomized, placebo-controlled study.

Type 2 Diabetes Mellitus

Boston University27 participantsStarted Jul 2013

Boston, Massachusetts, United States

COMPLETEDNA< 1 mile

Integration of Continuous Glucose Monitoring Into a BiHormonal Closed-Loop Artificial Pancreas

NCT01161862

The investigators hypothesize that our closed-loop glucose-control system can provide BG control in subjects with type 1 diabetes using the estimated BG signal from a CGM as the input signal to the controller.

Diabetes Mellitus

Boston University Charles River Campus24 participantsStarted Jul 2010

Boston, Massachusetts, United States

COMPLETEDPHASE2< 1 mile

Dose-Ranging Study In Subjects With Type 2 Diabetes Mellitus Who Are Treatment-Naive

NCT00495469

This is a dose-ranging study to evaluate the efficacy, safety and tolerability of a range of doses of GSK189075 (an SGLT2 inhibitor) compared to placebo, administered over 12 weeks in treatment-naive subjects with type 2 diabetes mellitus

Diabetes Mellitus, Type 2

GlaxoSmithKline250 participantsStarted Aug 2007

Mesa, Arizona, United States • Artesia, California, United States • Buena Park, California, United States +154 more locations

Dose-Dependent Effects of Erythritol on Endothelial Function in Type 2 Diabetes Mellitus

Integration of Continuous Glucose Monitoring Into a BiHormonal Closed-Loop Artificial Pancreas

Dose-Ranging Study In Subjects With Type 2 Diabetes Mellitus Who Are Treatment-Naive

Diabetes Trials in Other Cities

Effect of Ethanol Intoxication on the Anti-Hypoglycemic Action of Glucagon

UTLight-transcranial Doppler Assessment of Regional Cerebral Autoregulation

Liraglutide in Obesity and Diabetes: Identification of CNS Targets Using fMRI

Effect of Dietary Fat on Glycemic Control in Type 1 Diabetes

Glycemic Index - Variability Among Individuals

Comparing Google With A Focused Diabetes Search Engine

Thiazolidinedione Intervention With Vitamin D Evaluation

Dual Action of Liraglutide and Insulin Degludec in Type 2 Diabetes: A Trial Comparing the Efficacy and Safety of Insulin Degludec/Liraglutide, Insulin Degludec and Liraglutide in Subjects With Type 2 Diabetes

A Clinical Trial Comparing Efficacy and Safety of Insulin Degludec/Liraglutide (IDegLira) in Subjects With Type 2 Diabetes Mellitus Using Two Different Titration Algorithms

TRX4 Monoclonal Antibody in Type 1 Diabetes (T1 DM)

Safety and Efficacy of Combination Saxagliptin & Dapagliflozin Added to Metformin to Treat Subjects With Type 2 Diabetes

GAPP 1 Survey: Global Attitudes of Patients and Physicians in Insulin Therapy for Diabetes Mellitus

Dose-Ranging Study in Treatment Naive Type 2 Diabetes Mellitus(T2DM)

Study to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetics of Saxagliptin as Monotherapy in Pediatric Patients With Type 2 Diabetes

Evaluate Safety of Technosphere® Insulin (TI) in Diabetic Subjects With Moderate Obstructive Pulmonary Disease

A 2-Part Trial in Subjects With Type 2 Diabetes and in Healthy Subjects to Evaluate GSK1614235, a New Glucose Lowering Drug to Treat Type 2 Diabetes

A Study To Assess The Safety And Tolerability Of GSK189075 When Given With A Total Daily Dose Of >/ 2000mg of Metformin

Other Conditions in Boston