COVID-19 Clinical Trials

Showing 81-100 of 3,396 trials

Immunogenicity and Safety of a Booster Vaccination With a Recombinant Protein RBD Candidate Vaccine Against SARS-CoV-2 in Healthy Adults Volunteers Fully Vaccinated Followed by an Extension Period to Study a Fourth Dose Administration.

NCT05142553

This Phase IIb clinical study aims to compare the immunogenicity and safety of a booster dose of recombinant protein RBD fusion dimer vaccine as a heterologous booster (to subjects who have received the second dose of the Pfizer-BioNTech (Comirnaty) COVID-19 vaccine at least 182 days prior to the booster dose in this study) versus a homologous booster (subjects who received the second dose of the Comirnaty COVID-19 vaccine at least 182 days prior to the booster dose in this study) will receive a third dose of the Comirnaty vaccine). The extension part of the study aims to compare the immunogenicity and safety of a fourth dose of PHH-1V in subjects with a primovaccination with Pfizer-BioNTech (Comirnaty) COVID-19 vaccine plus either a booster dose of Comirnaty or PHH-1V versus those with three vaccinations of Comirnaty.

COVID-19SARS-CoV-2 Acute Respiratory Disease

Hipra Scientific, S.L.U887 participantsStarted Nov 2021

Badalona, BARCELONA, Spain • Barcelona, BARCELONA, Spain • Barcelona, Barcelona, Spain +7 more locations

RECRUITINGNA

Autoimmune Intervention Mastery Course Study

NCT05057676

The goal of this project is to critically evaluate the effectiveness of using an online program to improve diet and self-care in patients with multiple sclerosis (MS), clinically isolated syndrome (CIS), fibromyalgia, post acute sequela of covid, and cancer in remission with persisting fatigue.

Multiple SclerosisClinically Isolated SyndromeFibromyalgia+2 more

Terry L. Wahls400 participantsStarted Dec 2021

Iowa City, Iowa, United States

Immunogenicity and Safety of a Booster Vaccination With a Recombinant Protein RBD Candidate Vaccine Against SARS-CoV-2 in Healthy Adults Volunteers Fully Vaccinated Followed by an Extension Period to Study a Fourth Dose Administration.

Autoimmune Intervention Mastery Course Study

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