Finding studies
Finding studies
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Lead
National Institute of Allergy and Infectious Diseases (NIAID)
Study Description: This is a longitudinal cohort study to evaluate the clinical sequelae of acute COVID-19 and characterize the immune response to SARS-CoV-2. Household contacts of the COVID-19 cohort will also be recruited and serve as a control group. Objectives: * Characterize the medical sequalae and persistent symptoms following recovery from COVID-19 in a cohort of disease survivors. * Estimate the incidence and risk factors for post-COVID-19 medical sequalae. * Characterize antibody and cell-mediated immune responses to SARS-CoV- 2 in disease survivors * Characterize evolution of the antibody and T cell-mediated responses to SARS-CoV-2 in survivors over time * Evaluate survivors for evidence of re-infection with future waves of COVID-19 to determine if initial infection confers long-term protective immunity * Determine the incidence of clinically silent infection in household contacts * Characterize the mental health status of survivors and controls including medical trauma related sequelae Endpoint: Establish a clinically well characterized cohort of persons recovered from COVID-19 and close contacts of persons with COVID-19
Age
18–120
Sex
ALL
Healthy volunteers
Not accepted