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Clareo Health | Colorectal Cancer Clinical Trials in Tennessee | 449 Studies

Clinical Trials Colorectal CancerTennessee

Colorectal Cancer Clinical Trials in Tennessee

Find 449 clinical trials for colorectal cancer near Tennessee. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Tennessee

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RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 341-360 of 449 trials

RecruitingPhase 1/2 Trial of S241656 in Selected RAS/MAPK Mutation- Positive MalignanciesBDTX-4933-101 is a first-in-human, open-label, Phase 1/2 dose escalation, dose optimization and expansion study designed to evaluate the safety and tolerability of S241656 as…NCT05786924·Gilbert, Arizona and 48 others

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Data from ClinicalTrials.govTerms

CompletedOxaliplatin in Treating Patients With Recurrent Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00017082·Washington D.C., District of Columbia and 9 others

RecruitingA Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid TumorsThis is an open label, multicenter, phase 1/2 study to assess the safety/tolerability and preliminary clinical activity of STAR0602 as a single agent and in combination with…NCT05592626·Sacramento, California and 18 others

CompletedBlood and Stool Sample Collection in Subjects Participating in Colorectal Cancer Screening: Act BoldThe primary objective of this study is to collect de-identified, clinically-characterized stool and whole blood specimens for use in developing and evaluating the performance of…NCT03821948·Tempe, Arizona and 39 others

TerminatedPhase I/II Study of KRN330 Plus Irinotecan in Patients With Metastatic Colorectal CancerThe primary objective of the Phase II portion of this study is to assess the efficacy of KRN330 in combination with irinotecan after first-line or adjuvant FOLFOX (5-fluorouracil…NCT00838578·Huntsville, Alabama and 11 others

CompletedA Study of Ramucirumab or Icrucumab in Colorectal CancerThe purpose of this study is to determine if participants with metastatic colorectal cancer live longer without their cancer progressing when treated with standard chemotherapy…NCT01111604·Cincinnati, Ohio and 16 others

RecruitingA Study of Bispecific Antibody MCLA-158 in Patients With Advanced Solid TumorsThis is a Phase 1/2 open-label, multi-center, multi-national study with an initial dose escalation part to determine the recommended Phase II dose (RP2D) of MCLA-158 single agent…NCT03526835·La Jolla, California and 53 others

TerminatedCombination Chemotherapy Plus Trastuzumab in Treating Patients With Advanced, Recurrent, or Metastatic Colorectal CancerRATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die.NCT00006015·Birmingham, Alabama and 46 others

CompletedAI-EMERGE: Development and Validation of a Multi-analyte, Blood-based Colorectal Cancer Screening TestFreenome is using a type of artificial intelligence, called machine learning, to identify patterns of cell-free biomarkers in blood to detect cancer early.NCT03688906·Huntsville, Alabama and 29 others

CompletedA Multiple Ascending Dose Study of MEDI7247 in Advanced or Metastatic Solid TumorsTo assess safety and tolerability, describe the dose-limiting toxicities, assess the preliminary antitumor activity, determine the maximum tolerated dose (MTD) or the highest…NCT03811652·Huntersville, North Carolina and 2 others

RecruitingA Phase 1/2 Study of VS-7375 in Patients With KRAS G12D-Mutated Solid TumorsThis study will assess the safety and efficacy of VS-7375 alone and in combination in patients with advanced solid tumors harboring a KRAS G12D-mutation.NCT07020221·Los Angeles, California and 13 others

RecruitingCT-95 in Advanced Cancers Associated With Mesothelin ExpressionThis is a Phase 1a/1b, first-in-human (FIH), open-label, multi-center dose escalation and expansion study of the safety, pharmacokinetics (PK), pharmacodynamics, and antitumor…NCT06756035·Denver, Colorado and 8 others

Active not recruitingAn Open-Label Study to Enable Continued Treatment Access for Subjects Previously Enrolled in Studies of RuxolitinibThe purpose of this study is to provide continued supply of ruxolitinib alone, ruxolitinib plus background cancer therapy, or background cancer therapy alone to subjects from an…NCT02955940·Santa Monica, California and 8 others

CompletedA Phase 1 Clinical Study of AZD4635 in Patients With Advanced Solid MalignanciesThis is a Phase 1, open-label, multicenter study of continuous oral dosing of AZD4635 administered to patients with advanced solid malignancies.NCT02740985·Fayetteville, Arkansas and 16 others

RecruitingTesting the Addition of an Anti-Cancer Drug, ZEN003694, to the Usual Chemotherapy Treatment (Capecitabine) for Metastatic or Unresectable CancersThis phase I trial tests the safety, side effects, and best dose of ZEN003694 in combination with the usual treatment with capecitabine in treating patients with cancer that has…NCT05803382·Irvine, California and 21 others

CompletedA Study of CTX-009 in Adult Patients With Metastatic Colorectal CancerThis study is designed as an open-label, adaptive Simon Two-Stage study to evaluate the efficacy of CTX-009 in patients with metastatic colorectal cancer.NCT05513742·Hot Springs, Arkansas and 6 others

UnknownA Study to Assess PV-10 Chemoablation of Cancer of the LiverThis open-label study will evaluate the safety, tolerability, pharmacokinetics and effect on tumor growth following a single intralesional injection of PV-10 in subjects with…NCT00986661·San Diego, California and 4 others

Active not recruitingA Study of Botensilimab and Balstilimab for the Treatment of Colorectal CancerThis is an open-label, Phase 2, multicenter study to evaluate the efficacy, safety, tolerability, and pharmacokinetic profiles of botensilimab as monotherapy and in combination…NCT05608044·Scottsdale, Arizona and 64 others

RecruitingStudy of Elironrasib and Daraxonrasib as Monotherapies and Combination Therapy in Participants With Advanced KRAS G12C Mutant Solid TumorsThis study is to evaluate the safety, tolerability, and PK profiles of Elironrasib and Daraxonrasib as monotherapies and combination therapy in patients with KRAS G12C-mutated…NCT06128551·Duarte, California and 55 others

CompletedA Study of Epacadostat in Combination With Pembrolizumab and Chemotherapy in Participants With Advanced or Metastatic Solid Tumors (ECHO-207/KEYNOTE-723)This was an open-label, nonrandomized, Phase 1/2 study designed to determine the safety, tolerability, and efficacy of epacadostat when given in combination with pembrolizumab and…NCT03085914·Phoenix, Arizona and 15 others

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