Saves the questions and what to expect into your notes, next to the visit they belong to.
Keep this study
Lead
AbbVie
Age
18–any
Sex
ALL
Healthy volunteers
Not accepted
You may be eligible if
Participants with histologically or cytologically confirmed advanced metastatic or unresectable colorectal cancer (CRC) that is relapsed, refractory, or progressive following at least 2 prior systemic regimens in the metastatic setting.
Participants with an Eastern Cooperative Oncology Group (ECOG) of 0 - 1.
Participants with adequate hematologic, hepatic, and renal function.
You may not be if
Participants with prior exposure to a pyrrolobenzodiazepine or indolinobenzodiazepine based drug.
History of inflammatory bowel disease
Active autoimmune disease, with exception of psoriasis not requiring systemic treatment, vitiligo, type 1 diabetes mellitus and hypothyroidism
History of primary immunodeficiency, allogenic bone marrow transplantation, solid organ transplantation, or previous clinical diagnosis of tuberculosis
History of immune-mediated pneumonitis
Current or prior use of immunosuppressive medication within 14 days prior to the first dose of study treatment
