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Clareo Health | Colorectal Cancer Clinical Trials in Tennessee | 449 Studies

Clinical Trials Colorectal CancerTennessee

Colorectal Cancer Clinical Trials in Tennessee

Find 449 clinical trials for colorectal cancer near Tennessee. Connect with research centers in your area.

All Colorectal Cancer trials nationwide All trials in Tennessee

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Status

RecruitingNot yet recruitingActive, not recruitingEnrolling by invitationCompletedTerminated

Phase

Early phase 1Phase 1Phase 1–2Phase 2Phase 2–3Phase 3Phase 4No phase

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Showing 321-340 of 449 trials

CompletedRadiation Therapy Plus Chemotherapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the RectumRATIONALE: Radiation therapy uses high-energy x-rays to damage tumor cells.NCT00006366·Birmingham, Alabama and 234 others

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Data from ClinicalTrials.govTerms

CompletedA Study of RGX-202-01 (Ompenaclid) as Combination Therapy in RAS Mutant Advanced Colorectal CancerThis is a Phase 1 study currently evaluating PO administered ompenaclid in combination with FOLFIRI and bevacizumab in patients with advanced (i.e., locally advanced and…NCT03597581·Prescott Valley, Arizona and 16 others

TerminatedStudy of ADCT-301 in Patients With Selected Advanced Solid TumorsThis study evaluates ADCT-301 in patients with Selected Advanced Solid Tumors.NCT03621982·Palo Alto, California and 8 others

CompletedA Study of Napabucasin (BBI-608) in Combination With FOLFIRI in Adult Patients With Previously Treated Metastatic Colorectal CancerThis is an international multi-center, prospective, open-label, randomized, adaptive design phase 3 trial of the cancer stem cell pathway inhibitor napabucasin plus standard…NCT02753127·Birmingham, Alabama and 210 others

Active not recruitingA Study Assessing Adverse Events and Disease Activity of Intravenously (IV) Infused Telisotuzumab Adizutecan in Adult Participants With c-Met Protein Above Cutoff Level Above Refractory Metastatic Colorectal CancerColorectal cancer (CRC) is the third most common type of cancer diagnosed worldwide and in China.NCT06614192·Duarte, California and 50 others

CompletedTGR-1202 Alone and in Combination With Either Nab-paclitaxel + Gemcitabine or With FOLFOX in Patients With Select Relapsed or Refractory Solid TumorsThis is a Phase 1 multi-center study to assess the safety and efficacy of TGR-1202 as a single agent or in combination with nab-paclitaxel + gemcitabine or with FOLFOX in patients…NCT02574663·Nashville, Tennessee

CompletedGenetic Study of Young Patients With Colorectal CancerRATIONALE: Identifying gene mutations (microsatellite instability) may allow doctors to plan effective treatment for patients who develop colorectal cancer at an early age.NCT00044967·Mobile, Alabama and 72 others

CompletedA Study of a Personalized Neoantigen Cancer VaccineThe purpose of this study is to evaluate the safety, dose, immunogenicity and early clinical activity of GRT-C901 and GRT-R902, a personalized neoantigen cancer vaccine, in…NCT03639714·Phoenix, Arizona and 10 others

TerminatedA Study of SGN-MesoC2 in Advanced Solid TumorsThis clinical trial is studying advanced solid tumors. Solid tumors are cancers that start in a part of your body like your lungs or liver instead of your blood.NCT06466187·Birmingham, Alabama and 18 others

CompletedGlycan Mediated Immune Regulation With a Bi-Sialidase Fusion Protein (GLIMMER-01)This is a Phase 1/2, first-in-human, open-label, dose escalation and dose-expansion study of E-602, administered alone and in combination with cemiplimab.NCT05259696·La Jolla, California and 12 others

CompletedDose-Esc/Exp RMC4630 & Cobi in Relapsed/Refractory Solid Tumors & RMC4630& Osi in EGFR+ Locally Adv/Meta NSCLCThe purpose of this study is to evaluate the safety, tolerability, pharmacokinetic (PK), and pharmacodynamic (PD) proﬁles of RMC-4630 and cobimetinib in adult participants with…NCT03989115·Scottsdale, Arizona and 23 others

CompletedPrecision-Based Magnesium TrialColorectal cancer is the fourth most common incident cancer and the second most common cause of cancer death in the United States, with approximately 150,000 new cases and 57,000…NCT01105169·Nashville, Tennessee

RecruitingA Study of Tucatinib With Trastuzumab and mFOLFOX6 Versus Standard of Care Treatment in First-line HER2+ Metastatic Colorectal CancerThis study is being done to find out if tucatinib with other cancer drugs works better than standard of care to treat participants with HER2 positive colorectal cancer.NCT05253651·Glendale, Arizona and 365 others

CompletedStudy to Evaluate the Safety, Pharmacokinetics, and Activity of GDC-1971 in Combination With Either Osimertinib in Participants With Unresectable, Locally Advanced, or Metastatic Non-Small Cell Lung Cancer, or With Cetuximab in Participants With Metastatic Colorectal CancerThe main purpose of the study is to evaluate the safety of GDC-1971 in combination with either osimertinib or cetuximab.NCT05954871·Nashville, Tennessee and 5 others

CompletedAn Open Label Study Evaluating the Efficacy and Safety of Etrumadenant (AB928) Based Treatment Combinations in Participants With Metastatic Colorectal Cancer.This randomized phase 1b/2 open-label study will evaluate the antitumour activity and safety of etrumadenant (AB928) treatment combinations in participants with metastatic…NCT04660812·Tucson, Arizona and 43 others

Active not recruitingM6620 and Irinotecan Hydrochloride in Treating Patients With Solid Tumors That Are Metastatic or Cannot Be Removed by SurgeryThis phase I trial studies the side effects and best dose of M6620 and irinotecan hydrochloride in treating patients with solid tumors that have spread to other places in the body…NCT02595931·Los Angeles, California and 22 others

RecruitingDose Escalation and Dose Expansion Study of MDX2001 in Patients With Advanced Solid TumorsThis study is designed to characterize the safety, tolerability, and anti-tumor activity of MDX2001 in patients with advanced solid tumors.NCT06239194·Denver, Colorado and 5 others

CompletedStudy on the Effectiveness and Safety of the Combination of the Two Drugs Regorafenib and Nivolumab in Patients With Colorectal Cancer (Cancer of the Colon or Rectum Classified as Proficient Mismatch Repair and Microsatellite Stable)The purpose of this study is to learn if combination of the two drugs regorafenib and nivolumab is an effective treatment for pMMR - MSS colorectal cancer, a special type of…NCT04126733·Duarte, California and 14 others

CompletedA Study of the Safety and Tolerability of ABBV-621 in Participants With Previously-Treated Solid Tumors and Hematologic MalignanciesThis is an open-label, Phase I, dose-escalation study to determine the maximum tolerated dose (MTD) and/or recommended phase two dose (RPTD), and evaluate the safety, efficacy…NCT03082209·New Haven, Connecticut and 18 others

CompletedMicroOrganoSphere (MOS) Drug Screen Pilot Trial in Colorectal CancerThe purpose of the study is to determine the feasibility of generating sufficient MicroOrganoSpheres (MOS) from a biopsy of a subject's adenocarcinoma of the colon and/or rectum…NCT05189171·Scottsdale, Arizona and 6 others

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Other Conditions in Tennessee

Breast Cancer Lung Cancer Prostate Cancer Melanoma Leukemia Lymphoma